Detection of KRAS mutations in liquid biopsies from metastatic colorectal cancer patients using droplet digital PCR, Idylla, and next generation sequencing

Matilda Holm; Emma Andersson; Emerik Osterlund; Ali Ovissi; Leena-Maija Soveri; Anna-Kaisa Anttonen; Soili Kytölä; Kristiina Aittomäki; Pia Osterlund; Ari Ristimäki

doi:10.1371/journal.pone.0239819

Detection of KRAS mutations in liquid biopsies from metastatic colorectal cancer patients using droplet digital PCR, Idylla, and next generation sequencing

Matilda Holm, Emma Andersson, Emerik Osterlund, Ali Ovissi, Leena-Maija Soveri, Anna-Kaisa Anttonen, Soili Kytölä, Kristiina Aittomäki, Pia Osterlund, Ari Ristimäki

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	0239819
Journal	PLoS One
Volume	15
Issue number	11
Number of pages	13
ISSN	1932-6203
DOIs	https://doi.org/10.1371/journal.pone.0239819
Publication status	Published - 25 Nov 2020
MoE publication type	A1 Journal article-refereed

Fields of Science

DNA
3111 Biomedicine
1184 Genetics, developmental biology, physiology

Access to Document

10.1371/journal.pone.0239819

journal.pone.0239819Final published version, 1.07 MBLicence: CC BY

Cite this

Holm, M., Andersson, E., Osterlund, E., Ovissi, A., Soveri, L.-M., Anttonen, A.-K., Kytölä, S., Aittomäki, K., Osterlund, P., & Ristimäki, A. (2020). Detection of KRAS mutations in liquid biopsies from metastatic colorectal cancer patients using droplet digital PCR, Idylla, and next generation sequencing. PLoS One, 15(11), Article 0239819. https://doi.org/10.1371/journal.pone.0239819

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author = "Matilda Holm and Emma Andersson and Emerik Osterlund and Ali Ovissi and Leena-Maija Soveri and Anna-Kaisa Anttonen and Soili Kyt{\"o}l{\"a} and Kristiina Aittom{\"a}ki and Pia Osterlund and Ari Ristim{\"a}ki",

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Holm, M, Andersson, E, Osterlund, E, Ovissi, A, Soveri, L-M, Anttonen, A-K , Kytölä, S , Aittomäki, K , Osterlund, P & Ristimäki, A 2020, 'Detection of KRAS mutations in liquid biopsies from metastatic colorectal cancer patients using droplet digital PCR, Idylla, and next generation sequencing', PLoS One, vol. 15, no. 11, 0239819. https://doi.org/10.1371/journal.pone.0239819

TY - JOUR

T1 - Detection of KRAS mutations in liquid biopsies from metastatic colorectal cancer patients using droplet digital PCR, Idylla, and next generation sequencing

AU - Holm, Matilda

AU - Andersson, Emma

AU - Osterlund, Emerik

AU - Ovissi, Ali

AU - Soveri, Leena-Maija

AU - Anttonen, Anna-Kaisa

AU - Kytölä, Soili

AU - Aittomäki, Kristiina

AU - Osterlund, Pia

AU - Ristimäki, Ari

PY - 2020/11/25

Y1 - 2020/11/25

KW - DNA

KW - 3111 Biomedicine

KW - 1184 Genetics, developmental biology, physiology

U2 - 10.1371/journal.pone.0239819

DO - 10.1371/journal.pone.0239819

M3 - Article

SN - 1932-6203

VL - 15

JO - PLoS One

JF - PLoS One

IS - 11

M1 - 0239819

ER -