Development of siRNA and Budesonide Dual-Loaded Hybrid Lipid-Polymer Nanoparticles by Microfluidics Technology as a Platform for Dual Drug Delivery to Macrophages: An In Vitro Mechanistic Study

Sandra Lopez Cerda; Flavia Fontana; Shiqi Wang; Alexandra Correia; Giuseppina Molinaro; Ruben Pareja Tello; Jouni Hirvonen; Christian Celia; Goncalo Barreto; Helder A. Santos

doi:10.1002/adtp.202300048

Development of siRNA and Budesonide Dual-Loaded Hybrid Lipid-Polymer Nanoparticles by Microfluidics Technology as a Platform for Dual Drug Delivery to Macrophages: An In Vitro Mechanistic Study

Sandra Lopez Cerda, Flavia Fontana, Shiqi Wang, Alexandra Correia, Giuseppina Molinaro, Ruben Pareja Tello, Jouni Hirvonen, Christian Celia, Goncalo Barreto, Helder A. Santos

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	2300048
Journal	Advanced Therapeutics
Volume	6
Issue number	8
Number of pages	16
ISSN	2366-3987
DOIs	https://doi.org/10.1002/adtp.202300048
Publication status	Published - Aug 2023
MoE publication type	A1 Journal article-refereed

Fields of Science

317 Pharmacy

Access to Document

10.1002/adtp.202300048

Advanced Therapeutics - 2023 - CerdFinal published version, 2.26 MB

Cite this

Cerda, S. L., Fontana, F., Wang, S., Correia, A., Molinaro, G., Tello, R. P., Hirvonen, J., Celia, C., Barreto, G., & Santos, H. A. (2023). Development of siRNA and Budesonide Dual-Loaded Hybrid Lipid-Polymer Nanoparticles by Microfluidics Technology as a Platform for Dual Drug Delivery to Macrophages: An In Vitro Mechanistic Study. Advanced Therapeutics, 6(8), Article 2300048. https://doi.org/10.1002/adtp.202300048

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title = "Development of siRNA and Budesonide Dual-Loaded Hybrid Lipid-Polymer Nanoparticles by Microfluidics Technology as a Platform for Dual Drug Delivery to Macrophages: An In Vitro Mechanistic Study",

keywords = "Drug delivery, Hybrid nanoparticles, Macrophages, Microfluidics, siRNA, 317 Pharmacy",

author = "Cerda, {Sandra Lopez} and Flavia Fontana and Shiqi Wang and Alexandra Correia and Giuseppina Molinaro and Tello, {Ruben Pareja} and Jouni Hirvonen and Christian Celia and Goncalo Barreto and Santos, {Helder A.}",

year = "2023",

month = aug,

doi = "10.1002/adtp.202300048",

language = "English",

volume = "6",

journal = "Advanced Therapeutics",

issn = "2366-3987",

publisher = "Wiley-VCH",

number = "8",

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Cerda, SL, Fontana, F, Wang, S , Correia, A , Molinaro, G , Tello, RP , Hirvonen, J, Celia, C, Barreto, G & Santos, HA 2023, 'Development of siRNA and Budesonide Dual-Loaded Hybrid Lipid-Polymer Nanoparticles by Microfluidics Technology as a Platform for Dual Drug Delivery to Macrophages: An In Vitro Mechanistic Study', Advanced Therapeutics, vol. 6, no. 8, 2300048. https://doi.org/10.1002/adtp.202300048

Development of siRNA and Budesonide Dual-Loaded Hybrid Lipid-Polymer Nanoparticles by Microfluidics Technology as a Platform for Dual Drug Delivery to Macrophages: An In Vitro Mechanistic Study. / Cerda, Sandra Lopez; Fontana, Flavia; Wang, Shiqi et al.
In: Advanced Therapeutics, Vol. 6, No. 8, 2300048, 08.2023.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - Development of siRNA and Budesonide Dual-Loaded Hybrid Lipid-Polymer Nanoparticles by Microfluidics Technology as a Platform for Dual Drug Delivery to Macrophages

T2 - An In Vitro Mechanistic Study

AU - Cerda, Sandra Lopez

AU - Fontana, Flavia

AU - Wang, Shiqi

AU - Correia, Alexandra

AU - Molinaro, Giuseppina

AU - Tello, Ruben Pareja

AU - Hirvonen, Jouni

AU - Celia, Christian

AU - Barreto, Goncalo

AU - Santos, Helder A.

PY - 2023/8

Y1 - 2023/8

KW - Drug delivery

KW - Hybrid nanoparticles

KW - Macrophages

KW - Microfluidics

KW - siRNA

KW - 317 Pharmacy

U2 - 10.1002/adtp.202300048

DO - 10.1002/adtp.202300048

M3 - Article

SN - 2366-3987

VL - 6

JO - Advanced Therapeutics

JF - Advanced Therapeutics

IS - 8

M1 - 2300048

ER -