Distinct patterns of KRAS mutations in colorectal carcinomas according to germline mismatch repair defects and hMLH1 methylation status

C Oliveira, J L Westra, D Arango, M Ollikainen, E Domingo, A Ferreira, S Velho, R Niessen, K Lagerstedt, P Alhopuro, P Laiho, I Veiga, M R Teixeira, M Ligtenberg, J H Kleibeuker, R H Sijmons, J T Plukker, K Imai, P Lage, R HamelinC Albuquerque, S Schwartz, A Lindblom, P Peltomäki, H Yamamoto, L A Aaltonen, R Seruca, R M W Hofstra

    Research output: Contribution to journalArticleScientificpeer-review

    Original languageEnglish
    JournalHuman Molecular Genetics
    Volume13
    Pages (from-to)2303-2311
    Number of pages9
    ISSN0964-6906
    DOIs
    Publication statusPublished - 2004
    MoE publication typeA1 Journal article-refereed

    Fields of Science

    • NONPOLYPOSIS COLON-CANCER
    • RAS ONCOGENE ACTIVATION
    • MICROSATELLITE INSTABILITY
    • K-RAS
    • GENETIC ALTERATIONS
    • PROMOTER HYPERMETHYLATION
    • BRAF MUTATIONS
    • TUMORIGENESIS
    • CARCINOGENESIS
    • SEQUENCES
    • 311 Basic medicine

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