DNA-thioguanine nucleotide concentration and relapse-free survival during maintenance therapy of childhood acute lymphoblastic leukaemia (NOPHO ALL2008): a prospective substudy of a phase 3 trial

Stine Nygaard Nielsen; Kathrine Grell; Jacob Nersting; Jonas Abrahamsson; Bendik Lund; Jukka Kanerva; Olafur Gisli Jonsson; Goda Vaitkeviciene; Kaie Pruunsild; Lisa Lyngsie Hjalgrim; Kjeld Schmiegelow

doi:10.1016/S1470-2045(17)30154-7

DNA-thioguanine nucleotide concentration and relapse-free survival during maintenance therapy of childhood acute lymphoblastic leukaemia (NOPHO ALL2008): a prospective substudy of a phase 3 trial

Stine Nygaard Nielsen, Kathrine Grell, Jacob Nersting, Jonas Abrahamsson, Bendik Lund, Jukka Kanerva, Olafur Gisli Jonsson, Goda Vaitkeviciene, Kaie Pruunsild, Lisa Lyngsie Hjalgrim, Kjeld Schmiegelow

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Lancet Oncology
Volume	18
Issue number	4
Pages (from-to)	515-524
Number of pages	10
ISSN	1470-2045
DOIs	https://doi.org/10.1016/S1470-2045(17)30154-7
Publication status	Published - Apr 2017
MoE publication type	A1 Journal article-refereed

Fields of Science

ONCOLOGY GROUP
SYSTEMIC EXPOSURE
CLINICAL-TRIALS
CHILDREN
RISK
METHOTREXATE
THIOPURINES
CANCER
6-MERCAPTOPURINE
MERCAPTOPURINE
3123 Gynaecology and paediatrics
3122 Cancers

Access to Document

10.1016/S1470-2045(17)30154-7

Cite this

Nielsen, S. N., Grell, K., Nersting, J., Abrahamsson, J., Lund, B., Kanerva, J., Jonsson, O. G., Vaitkeviciene, G., Pruunsild, K., Hjalgrim, L. L., & Schmiegelow, K. (2017). DNA-thioguanine nucleotide concentration and relapse-free survival during maintenance therapy of childhood acute lymphoblastic leukaemia (NOPHO ALL2008): a prospective substudy of a phase 3 trial. Lancet Oncology, 18(4), 515-524. https://doi.org/10.1016/S1470-2045(17)30154-7

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title = "DNA-thioguanine nucleotide concentration and relapse-free survival during maintenance therapy of childhood acute lymphoblastic leukaemia (NOPHO ALL2008): a prospective substudy of a phase 3 trial",

keywords = "ONCOLOGY GROUP, SYSTEMIC EXPOSURE, CLINICAL-TRIALS, CHILDREN, RISK, METHOTREXATE, THIOPURINES, CANCER, 6-MERCAPTOPURINE, MERCAPTOPURINE, 3123 Gynaecology and paediatrics, 3122 Cancers",

author = "Nielsen, {Stine Nygaard} and Kathrine Grell and Jacob Nersting and Jonas Abrahamsson and Bendik Lund and Jukka Kanerva and Jonsson, {Olafur Gisli} and Goda Vaitkeviciene and Kaie Pruunsild and Hjalgrim, {Lisa Lyngsie} and Kjeld Schmiegelow",

year = "2017",

month = apr,

doi = "10.1016/S1470-2045(17)30154-7",

language = "English",

volume = "18",

pages = "515--524",

journal = "Lancet Oncology",

issn = "1470-2045",

publisher = "Elsevier Ltd. ",

number = "4",

}

Nielsen, SN, Grell, K, Nersting, J, Abrahamsson, J, Lund, B, Kanerva, J, Jonsson, OG, Vaitkeviciene, G, Pruunsild, K, Hjalgrim, LL & Schmiegelow, K 2017, 'DNA-thioguanine nucleotide concentration and relapse-free survival during maintenance therapy of childhood acute lymphoblastic leukaemia (NOPHO ALL2008): a prospective substudy of a phase 3 trial', Lancet Oncology, vol. 18, no. 4, pp. 515-524. https://doi.org/10.1016/S1470-2045(17)30154-7

DNA-thioguanine nucleotide concentration and relapse-free survival during maintenance therapy of childhood acute lymphoblastic leukaemia (NOPHO ALL2008): a prospective substudy of a phase 3 trial. / Nielsen, Stine Nygaard; Grell, Kathrine; Nersting, Jacob et al.
In: Lancet Oncology, Vol. 18, No. 4, 04.2017, p. 515-524.

Research output: Contribution to journal › Article › Scientific › peer-review

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AU - Nielsen, Stine Nygaard

AU - Grell, Kathrine

AU - Nersting, Jacob

AU - Abrahamsson, Jonas

AU - Lund, Bendik

AU - Kanerva, Jukka

AU - Jonsson, Olafur Gisli

AU - Vaitkeviciene, Goda

AU - Pruunsild, Kaie

AU - Hjalgrim, Lisa Lyngsie

AU - Schmiegelow, Kjeld

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KW - METHOTREXATE

KW - THIOPURINES

KW - CANCER

KW - 6-MERCAPTOPURINE

KW - MERCAPTOPURINE

KW - 3123 Gynaecology and paediatrics

KW - 3122 Cancers

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DO - 10.1016/S1470-2045(17)30154-7

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EP - 524

JO - Lancet Oncology

JF - Lancet Oncology

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