Dose-Dependent Interaction between Gemfibrozil and Repaglinide in Humans: Strong Inhibition of CYP2C8 with Subtherapeutic Gemfibrozil Doses

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalDrug Metabolism and Disposition
Volume39
Issue number10
Pages (from-to)1977-86
Number of pages10
ISSN0090-9556
DOIs
Publication statusPublished - 2011
MoE publication typeA1 Journal article-refereed

Fields of Science

  • HUMAN CYTOCHROME P4502C8
  • TRANSPORTING POLYPEPTIDE 1B1
  • MECHANISM-BASED INACTIVATION
  • DRUG-DRUG INTERACTIONS
  • HUMAN LIVER-MICROSOMES
  • PLASMA-CONCENTRATIONS
  • IN-VITRO
  • PHARMACOKINETICS PERSISTS
  • SLCO1B1 POLYMORPHISM
  • HEPATIC-UPTAKE
  • 3111 Biomedicine

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