Downregulation of tyrosine hydroxylase phenotype after AAV injection above substantia nigra: Caution in experimental models of Parkinson's disease

Katrina Albert, Merja H. Voutilainen, Andrii Domanskyi, T. Petteri Piepponen, Sari Ahola, Raimo K. Tuominen, Christopher Richie, Brandon K. Harvey, Mikko Airavaara

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalJournal of Neuroscience Research
Volume97
Issue number3
Pages (from-to)346-361
Number of pages16
ISSN0360-4012
DOIs
Publication statusPublished - Mar 2019
MoE publication typeA1 Journal article-refereed

Fields of Science

  • adeno-associated virus
  • alpha-synuclein
  • DIO
  • dopamine
  • GFP
  • Parkinson's disease
  • substantia nigra
  • HUMAN ALPHA-SYNUCLEIN
  • MIDBRAIN DOPAMINE NEURONS
  • RAT MODEL
  • MEDIATED OVEREXPRESSION
  • MESSENGER-RNA
  • GENE-TRANSFER
  • MOUSE MODEL
  • PROTEIN
  • CALCIUM
  • NEURODEGENERATION

Cite this

@article{4bbf528907e3491e86588ff62b238299,
title = "Downregulation of tyrosine hydroxylase phenotype after AAV injection above substantia nigra: Caution in experimental models of Parkinson's disease",
keywords = "adeno-associated virus, alpha-synuclein, DIO, dopamine, GFP, Parkinson's disease, substantia nigra, HUMAN ALPHA-SYNUCLEIN, MIDBRAIN DOPAMINE NEURONS, RAT MODEL, MEDIATED OVEREXPRESSION, MESSENGER-RNA, GENE-TRANSFER, MOUSE MODEL, PROTEIN, CALCIUM, NEURODEGENERATION",
author = "Katrina Albert and Voutilainen, {Merja H.} and Andrii Domanskyi and Piepponen, {T. Petteri} and Sari Ahola and Tuominen, {Raimo K.} and Christopher Richie and Harvey, {Brandon K.} and Mikko Airavaara",
year = "2019",
month = "3",
doi = "10.1002/jnr.24363",
language = "English",
volume = "97",
pages = "346--361",
journal = "Journal of Neuroscience Research",
issn = "0360-4012",
publisher = "Wiley",
number = "3",

}

Downregulation of tyrosine hydroxylase phenotype after AAV injection above substantia nigra : Caution in experimental models of Parkinson's disease. / Albert, Katrina; Voutilainen, Merja H.; Domanskyi, Andrii; Piepponen, T. Petteri; Ahola, Sari; Tuominen, Raimo K.; Richie, Christopher; Harvey, Brandon K.; Airavaara, Mikko.

In: Journal of Neuroscience Research, Vol. 97, No. 3, 03.2019, p. 346-361.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Downregulation of tyrosine hydroxylase phenotype after AAV injection above substantia nigra

T2 - Caution in experimental models of Parkinson's disease

AU - Albert, Katrina

AU - Voutilainen, Merja H.

AU - Domanskyi, Andrii

AU - Piepponen, T. Petteri

AU - Ahola, Sari

AU - Tuominen, Raimo K.

AU - Richie, Christopher

AU - Harvey, Brandon K.

AU - Airavaara, Mikko

PY - 2019/3

Y1 - 2019/3

KW - adeno-associated virus

KW - alpha-synuclein

KW - DIO

KW - dopamine

KW - GFP

KW - Parkinson's disease

KW - substantia nigra

KW - HUMAN ALPHA-SYNUCLEIN

KW - MIDBRAIN DOPAMINE NEURONS

KW - RAT MODEL

KW - MEDIATED OVEREXPRESSION

KW - MESSENGER-RNA

KW - GENE-TRANSFER

KW - MOUSE MODEL

KW - PROTEIN

KW - CALCIUM

KW - NEURODEGENERATION

U2 - 10.1002/jnr.24363

DO - 10.1002/jnr.24363

M3 - Article

VL - 97

SP - 346

EP - 361

JO - Journal of Neuroscience Research

JF - Journal of Neuroscience Research

SN - 0360-4012

IS - 3

ER -