Downregulation of tyrosine hydroxylase phenotype after AAV injection above substantia nigra: Caution in experimental models of Parkinson's disease

Katrina Albert; Merja H. Voutilainen; Andrii Domanskyi; T. Petteri Piepponen; Sari Ahola; Raimo K. Tuominen; Christopher Richie; Brandon K. Harvey; Mikko Airavaara

doi:10.1002/jnr.24363

Downregulation of tyrosine hydroxylase phenotype after AAV injection above substantia nigra: Caution in experimental models of Parkinson's disease

Katrina Albert, Merja H. Voutilainen, Andrii Domanskyi, T. Petteri Piepponen, Sari Ahola, Raimo K. Tuominen, Christopher Richie, Brandon K. Harvey, Mikko Airavaara

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Journal of Neuroscience Research
Volume	97
Issue number	3
Pages (from-to)	346-361
Number of pages	16
ISSN	0360-4012
DOIs	https://doi.org/10.1002/jnr.24363
Publication status	Published - Mar 2019
MoE publication type	A1 Journal article-refereed

Fields of Science

adeno-associated virus
alpha-synuclein
DIO
dopamine
GFP
Parkinson's disease
substantia nigra
HUMAN ALPHA-SYNUCLEIN
MIDBRAIN DOPAMINE NEURONS
RAT MODEL
MEDIATED OVEREXPRESSION
MESSENGER-RNA
GENE-TRANSFER
MOUSE MODEL
PROTEIN
CALCIUM
NEURODEGENERATION
3112 Neurosciences

Access to Document

10.1002/jnr.24363

Cite this

Albert, K., Voutilainen, M. H., Domanskyi, A., Piepponen, T. P., Ahola, S., Tuominen, R. K., Richie, C., Harvey, B. K., & Airavaara, M. (2019). Downregulation of tyrosine hydroxylase phenotype after AAV injection above substantia nigra: Caution in experimental models of Parkinson's disease. Journal of Neuroscience Research, 97(3), 346-361. https://doi.org/10.1002/jnr.24363

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title = "Downregulation of tyrosine hydroxylase phenotype after AAV injection above substantia nigra: Caution in experimental models of Parkinson's disease",

keywords = "adeno-associated virus, alpha-synuclein, DIO, dopamine, GFP, Parkinson's disease, substantia nigra, HUMAN ALPHA-SYNUCLEIN, MIDBRAIN DOPAMINE NEURONS, RAT MODEL, MEDIATED OVEREXPRESSION, MESSENGER-RNA, GENE-TRANSFER, MOUSE MODEL, PROTEIN, CALCIUM, NEURODEGENERATION, 3112 Neurosciences",

author = "Katrina Albert and Voutilainen, {Merja H.} and Andrii Domanskyi and Piepponen, {T. Petteri} and Sari Ahola and Tuominen, {Raimo K.} and Christopher Richie and Harvey, {Brandon K.} and Mikko Airavaara",

year = "2019",

month = mar,

doi = "10.1002/jnr.24363",

language = "English",

volume = "97",

pages = "346--361",

journal = "Journal of Neuroscience Research",

issn = "0360-4012",

publisher = "Wiley-Liss Inc.",

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}

Albert, K, Voutilainen, MH , Domanskyi, A , Piepponen, TP, Ahola, S, Tuominen, RK, Richie, C, Harvey, BK & Airavaara, M 2019, 'Downregulation of tyrosine hydroxylase phenotype after AAV injection above substantia nigra: Caution in experimental models of Parkinson's disease', Journal of Neuroscience Research, vol. 97, no. 3, pp. 346-361. https://doi.org/10.1002/jnr.24363

Downregulation of tyrosine hydroxylase phenotype after AAV injection above substantia nigra: Caution in experimental models of Parkinson's disease. / Albert, Katrina; Voutilainen, Merja H.; Domanskyi, Andrii et al.
In: Journal of Neuroscience Research, Vol. 97, No. 3, 03.2019, p. 346-361.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - Downregulation of tyrosine hydroxylase phenotype after AAV injection above substantia nigra

T2 - Caution in experimental models of Parkinson's disease

AU - Albert, Katrina

AU - Voutilainen, Merja H.

AU - Domanskyi, Andrii

AU - Piepponen, T. Petteri

AU - Ahola, Sari

AU - Tuominen, Raimo K.

AU - Richie, Christopher

AU - Harvey, Brandon K.

AU - Airavaara, Mikko

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KW - MIDBRAIN DOPAMINE NEURONS

KW - RAT MODEL

KW - MEDIATED OVEREXPRESSION

KW - MESSENGER-RNA

KW - GENE-TRANSFER

KW - MOUSE MODEL

KW - PROTEIN

KW - CALCIUM

KW - NEURODEGENERATION

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