Drug sensitivity profiling identifies potential therapies for lymphoproliferative disorders with overactive JAK/STAT3 signaling

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalOncotarget
Volume8
Issue number57
Pages (from-to)97516-97527
Number of pages12
ISSN1949-2553
DOIs
Publication statusPublished - 14 Nov 2017
MoE publication typeA1 Journal article-refereed

Fields of Science

  • STAT3 mutation
  • Hsp90 and JAK inhibitors
  • high-throughput compound screening
  • hematological malignancy
  • GRANULAR LYMPHOCYTIC-LEUKEMIA
  • EPSTEIN-BARR-VIRUS
  • STAT3 MUTATIONS
  • SERINE PHOSPHORYLATION
  • MAXIMAL ACTIVATION
  • MCL-1 EXPRESSION
  • CELL LYMPHOMAS
  • SMALL-MOLECULE
  • INHIBITOR
  • TARGET
  • 3122 Cancers

Cite this

@article{5f7adc5bbf164acf8969c11ad3109693,
title = "Drug sensitivity profiling identifies potential therapies for lymphoproliferative disorders with overactive JAK/STAT3 signaling",
keywords = "STAT3 mutation, Hsp90 and JAK inhibitors, high-throughput compound screening, hematological malignancy, GRANULAR LYMPHOCYTIC-LEUKEMIA, EPSTEIN-BARR-VIRUS, STAT3 MUTATIONS, SERINE PHOSPHORYLATION, MAXIMAL ACTIVATION, MCL-1 EXPRESSION, CELL LYMPHOMAS, SMALL-MOLECULE, INHIBITOR, TARGET, 3122 Cancers",
author = "Heikki Kuusanm{\"a}ki and Olli Dufva and Elina Parri and {van Adrichem}, {Arjan J.} and Hanna Rajala and Majumder, {Muntasir M.} and Bhagwan Yadav and Alun Parsons and Chan, {Wing C.} and Krister Wennerberg and Satu Mustjoki and Heckman, {Caroline A.}",
year = "2017",
month = "11",
day = "14",
doi = "10.18632/oncotarget.22178",
language = "English",
volume = "8",
pages = "97516--97527",
journal = "Oncotarget",
issn = "1949-2553",
publisher = "Impact Journals LLC",
number = "57",

}

TY - JOUR

T1 - Drug sensitivity profiling identifies potential therapies for lymphoproliferative disorders with overactive JAK/STAT3 signaling

AU - Kuusanmäki, Heikki

AU - Dufva, Olli

AU - Parri, Elina

AU - van Adrichem, Arjan J.

AU - Rajala, Hanna

AU - Majumder, Muntasir M.

AU - Yadav, Bhagwan

AU - Parsons, Alun

AU - Chan, Wing C.

AU - Wennerberg, Krister

AU - Mustjoki, Satu

AU - Heckman, Caroline A.

PY - 2017/11/14

Y1 - 2017/11/14

KW - STAT3 mutation

KW - Hsp90 and JAK inhibitors

KW - high-throughput compound screening

KW - hematological malignancy

KW - GRANULAR LYMPHOCYTIC-LEUKEMIA

KW - EPSTEIN-BARR-VIRUS

KW - STAT3 MUTATIONS

KW - SERINE PHOSPHORYLATION

KW - MAXIMAL ACTIVATION

KW - MCL-1 EXPRESSION

KW - CELL LYMPHOMAS

KW - SMALL-MOLECULE

KW - INHIBITOR

KW - TARGET

KW - 3122 Cancers

U2 - 10.18632/oncotarget.22178

DO - 10.18632/oncotarget.22178

M3 - Article

VL - 8

SP - 97516

EP - 97527

JO - Oncotarget

JF - Oncotarget

SN - 1949-2553

IS - 57

ER -