Dual interaction of factor H with C3d and glycosaminoglycans in host-nonhost discrimination by complement

Tommi Kajander, Markus Juhana Lehtinen, Satu Hyvärinen, Arnab Bhattacharjee, Elisa Leung, David E. Isenman, Seppo Meri, Adrian Goldman, T. Sakari Jokiranta

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalProceedings of the National Academy of Sciences of the United States of America
Volume108
Issue number7
Pages (from-to)2897-2902
Number of pages6
ISSN0027-8424
DOIs
Publication statusPublished - 2011
MoE publication typeA1 Journal article-refereed

Fields of Science

  • structure and function
  • X-ray crystallography
  • hemolysis
  • kidney diseases
  • human mutations
  • HEMOLYTIC-UREMIC SYNDROME
  • SURFACE-BOUND C3B
  • BINDING-SITE
  • SIALIC-ACID
  • ALTERNATIVE PATHWAY
  • REGULATORY DOMAINS
  • ENDOTHELIAL-CELLS
  • RECEPTOR 2
  • MUTATIONS
  • IDENTIFICATION

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