Early DNA methylation changes in children developing beta cell autoimmunity at a young age

Inna Starskaia; Essi Laajala; Toni Grönroos; Taina Härkönen; Sini Junttila; Roosa Kattelus; Henna Kallionpää; Asta Laiho; Veronika Suni; Vallo Tillmann; Riikka Lund; Laura L. Elo; Harri Lähdesmäki; Mikael Knip; Ubaid Ullah Kalim; Riitta Lahesmaa

doi:10.1007/s00125-022-05657-x

Early DNA methylation changes in children developing beta cell autoimmunity at a young age

Inna Starskaia, Essi Laajala, Toni Grönroos, Taina Härkönen, Sini Junttila, Roosa Kattelus, Henna Kallionpää, Asta Laiho, Veronika Suni, Vallo Tillmann, Riikka Lund, Laura L. Elo, Harri Lähdesmäki, Mikael Knip, Ubaid Ullah Kalim, Riitta Lahesmaa

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Diabetologia
Volume	65
Pages (from-to)	844-860
Number of pages	17
ISSN	0012-186X
DOIs	https://doi.org/10.1007/s00125-022-05657-x
Publication status	Published - May 2022
MoE publication type	A1 Journal article-refereed

Fields of Science

DNA methylation
Epigenetics
T cells
Type 1 diabetes
TYPE-1 DIABETES SUSCEPTIBILITY
GENOME-WIDE ASSOCIATION
RISK
LOCI
SEROCONVERSION
HAPLOTYPES
GENOTYPES
3121 General medicine, internal medicine and other clinical medicine

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10.1007/s00125-022-05657-xLicence: CC BY

Starskaia2022_Article_EarlyDNAMethylationChangesInChFinal published version, 1.68 MBLicence: CC BY

Cite this

Starskaia, I., Laajala, E., Grönroos, T., Härkönen, T., Junttila, S., Kattelus, R., Kallionpää, H., Laiho, A., Suni, V., Tillmann, V., Lund, R., Elo, L. L., Lähdesmäki, H., Knip, M., Kalim, U. U., & Lahesmaa, R. (2022). Early DNA methylation changes in children developing beta cell autoimmunity at a young age. Diabetologia, 65, 844-860. https://doi.org/10.1007/s00125-022-05657-x

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title = "Early DNA methylation changes in children developing beta cell autoimmunity at a young age",

keywords = "DNA methylation, Epigenetics, T cells, Type 1 diabetes, TYPE-1 DIABETES SUSCEPTIBILITY, GENOME-WIDE ASSOCIATION, RISK, LOCI, SEROCONVERSION, HAPLOTYPES, GENOTYPES, 3121 General medicine, internal medicine and other clinical medicine",

author = "Inna Starskaia and Essi Laajala and Toni Gr{\"o}nroos and Taina H{\"a}rk{\"o}nen and Sini Junttila and Roosa Kattelus and Henna Kallionp{\"a}{\"a} and Asta Laiho and Veronika Suni and Vallo Tillmann and Riikka Lund and Elo, {Laura L.} and Harri L{\"a}hdesm{\"a}ki and Mikael Knip and Kalim, {Ubaid Ullah} and Riitta Lahesmaa",

year = "2022",

month = may,

doi = "10.1007/s00125-022-05657-x",

language = "English",

volume = "65",

pages = "844--860",

journal = "Diabetologia",

issn = "0012-186X",

publisher = "Springer Science and Business Media Deutschland GmbH",

}

Starskaia, I, Laajala, E, Grönroos, T, Härkönen, T, Junttila, S, Kattelus, R, Kallionpää, H, Laiho, A, Suni, V, Tillmann, V, Lund, R, Elo, LL, Lähdesmäki, H, Knip, M, Kalim, UU & Lahesmaa, R 2022, 'Early DNA methylation changes in children developing beta cell autoimmunity at a young age', Diabetologia, vol. 65, pp. 844-860. https://doi.org/10.1007/s00125-022-05657-x

TY - JOUR

T1 - Early DNA methylation changes in children developing beta cell autoimmunity at a young age

AU - Starskaia, Inna

AU - Laajala, Essi

AU - Grönroos, Toni

AU - Härkönen, Taina

AU - Junttila, Sini

AU - Kattelus, Roosa

AU - Kallionpää, Henna

AU - Laiho, Asta

AU - Suni, Veronika

AU - Tillmann, Vallo

AU - Lund, Riikka

AU - Elo, Laura L.

AU - Lähdesmäki, Harri

AU - Knip, Mikael

AU - Kalim, Ubaid Ullah

AU - Lahesmaa, Riitta

PY - 2022/5

Y1 - 2022/5

KW - DNA methylation

KW - Epigenetics

KW - T cells

KW - Type 1 diabetes

KW - TYPE-1 DIABETES SUSCEPTIBILITY

KW - GENOME-WIDE ASSOCIATION

KW - RISK

KW - LOCI

KW - SEROCONVERSION

KW - HAPLOTYPES

KW - GENOTYPES

KW - 3121 General medicine, internal medicine and other clinical medicine

U2 - 10.1007/s00125-022-05657-x

DO - 10.1007/s00125-022-05657-x

M3 - Article

SN - 0012-186X

VL - 65

SP - 844

EP - 860

JO - Diabetologia

JF - Diabetologia

ER -