Effect of High-Dose Esomeprazole on CYP1A2, CYP2C19, and CYP3A4 Activities in Humans: Evidence for Substantial and Long-lasting Inhibition of CYP2C19

Taavi J. K. Kaartinen, Aleksi Tornio, Tuija Tapaninen, Terhi Launiainen, Nina Isoherranen, Mikko Niemi, Janne T. Backman

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalClinical Pharmacology and Therapeutics
Volume108
Issue number6
Pages (from-to)1254-1264
Number of pages11
ISSN0009-9236
DOIs
Publication statusPublished - Dec 2020
MoE publication typeA1 Journal article-refereed

Fields of Science

  • PROTON PUMP INHIBITOR
  • IN-VITRO
  • STEREOSELECTIVE PHARMACOKINETICS
  • DEPENDENT INHIBITOR
  • DRUG-INTERACTION
  • PH PROFILES
  • BREATH TEST
  • OMEPRAZOLE
  • METABOLISM
  • CYTOCHROME-P450
  • 317 Pharmacy
  • 3111 Biomedicine

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