Effect of level of sedation on outcomes in critically ill adult patients: a systematic review of clinical trials with meta-analysis and trial sequential analysis

Ameldina Ceric; Johan Holgersson; Teresa L. May; Markus B. Skrifvars; Johanna Hästbacka; Manoj Saxena; Anders Aneman; Anthony Delaney; Michael C. Reade; Candice Delcourt; Janus Christian Jakobsen; Niklas Nielsen

doi:10.1016/j.eclinm.2024.102569

Effect of level of sedation on outcomes in critically ill adult patients: a systematic review of clinical trials with meta-analysis and trial sequential analysis

Ameldina Ceric, Johan Holgersson, Teresa L. May, Markus B. Skrifvars, Johanna Hästbacka, Manoj Saxena, Anders Aneman, Anthony Delaney, Michael C. Reade, Candice Delcourt, Janus Christian Jakobsen, Niklas Nielsen

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	102569
Journal	EClinicalMedicine
Volume	71
Number of pages	12
ISSN	2589-5370
DOIs	https://doi.org/10.1016/j.eclinm.2024.102569
Publication status	Published - May 2024
MoE publication type	A1 Journal article-refereed

Fields of Science

3121 General medicine, internal medicine and other clinical medicine

Access to Document

10.1016/j.eclinm.2024.102569

1-s2.0-S2589537024001482-mainFinal published version, 910 KBLicence: CC BY

Cite this

Ceric, A., Holgersson, J., May, T. L., Skrifvars, M. B., Hästbacka, J., Saxena, M., Aneman, A., Delaney, A., Reade, M. C., Delcourt, C., Jakobsen, J. C., & Nielsen, N. (2024). Effect of level of sedation on outcomes in critically ill adult patients: a systematic review of clinical trials with meta-analysis and trial sequential analysis. EClinicalMedicine, 71, Article 102569. https://doi.org/10.1016/j.eclinm.2024.102569

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title = "Effect of level of sedation on outcomes in critically ill adult patients: a systematic review of clinical trials with meta-analysis and trial sequential analysis",

keywords = "Critically ill, Denmark, Intensive care, Meta -analysis, Mortality, Sedation, Systematic review, 3121 General medicine, internal medicine and other clinical medicine",

author = "Ameldina Ceric and Johan Holgersson and May, {Teresa L.} and Skrifvars, {Markus B.} and Johanna H{\"a}stbacka and Manoj Saxena and Anders Aneman and Anthony Delaney and Reade, {Michael C.} and Candice Delcourt and Jakobsen, {Janus Christian} and Niklas Nielsen",

year = "2024",

month = may,

doi = "10.1016/j.eclinm.2024.102569",

language = "English",

volume = "71",

journal = "EClinicalMedicine",

issn = "2589-5370",

publisher = "Elsevier Ltd. ",

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Ceric, A, Holgersson, J, May, TL, Skrifvars, MB , Hästbacka, J, Saxena, M, Aneman, A, Delaney, A, Reade, MC, Delcourt, C, Jakobsen, JC & Nielsen, N 2024, 'Effect of level of sedation on outcomes in critically ill adult patients: a systematic review of clinical trials with meta-analysis and trial sequential analysis', EClinicalMedicine, vol. 71, 102569. https://doi.org/10.1016/j.eclinm.2024.102569

TY - JOUR

T1 - Effect of level of sedation on outcomes in critically ill adult patients

T2 - a systematic review of clinical trials with meta-analysis and trial sequential analysis

AU - Ceric, Ameldina

AU - Holgersson, Johan

AU - May, Teresa L.

AU - Skrifvars, Markus B.

AU - Hästbacka, Johanna

AU - Saxena, Manoj

AU - Aneman, Anders

AU - Delaney, Anthony

AU - Reade, Michael C.

AU - Delcourt, Candice

AU - Jakobsen, Janus Christian

AU - Nielsen, Niklas

PY - 2024/5

Y1 - 2024/5

KW - Critically ill

KW - Denmark

KW - Intensive care

KW - Meta -analysis

KW - Mortality

KW - Sedation

KW - Systematic review

KW - 3121 General medicine, internal medicine and other clinical medicine

U2 - 10.1016/j.eclinm.2024.102569

DO - 10.1016/j.eclinm.2024.102569

M3 - Article

SN - 2589-5370

VL - 71

JO - EClinicalMedicine

JF - EClinicalMedicine

M1 - 102569

ER -