Effective treatment of mitochondrial myopathy by nicotinamide riboside, a vitamin B3

Nahid A. Khan; Mari Auranen; Ilse Paetau; Eija Pirinen; Liliya Euro; Saara Forsström; Lotta Pasila; Vidya Velagapudi; Christopher J. Carroll; Johan Auwerx; Anu Suomalainen

doi:10.1002/emmm.201403943

Effective treatment of mitochondrial myopathy by nicotinamide riboside, a vitamin B3

Nahid A. Khan, Mari Auranen, Ilse Paetau, Eija Pirinen, Liliya Euro, Saara Forsström, Lotta Pasila, Vidya Velagapudi, Christopher J. Carroll, Johan Auwerx, Anu Suomalainen

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	EMBO molecular medicine
Volume	6
Issue number	6
Pages (from-to)	721-731
Number of pages	11
ISSN	1757-4676
DOIs	https://doi.org/10.1002/emmm.201403943
Publication status	Published - Jun 2014
MoE publication type	A1 Journal article-refereed

Fields of Science

mitochondrial myopathy
NAD(+)
nicotinamide riboside
treatment
unfolded protein response
PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA
UNFOLDED-PROTEIN RESPONSE
MULTIPLE DELETIONS
ACTIVATION
LONGEVITY
PGC-1-ALPHA
DISEASE
SIRT1
DEACETYLASE
3111 Biomedicine

Access to Document

10.1002/emmm.201403943

Effective treatmentFinal published version, 3.42 MBLicence: CC BY

FIMM Metabolomics (LS-RIA/ Metabo-HiLIFE)
Nieminen, A. I. (Manager)
Institute for Molecular Medicine Finland
Facility/equipment: Core Facility

Cite this

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title = "Effective treatment of mitochondrial myopathy by nicotinamide riboside, a vitamin B3",

keywords = "mitochondrial myopathy, NAD(+), nicotinamide riboside, treatment, unfolded protein response, PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA, UNFOLDED-PROTEIN RESPONSE, MULTIPLE DELETIONS, ACTIVATION, LONGEVITY, PGC-1-ALPHA, DISEASE, SIRT1, DEACETYLASE, 3111 Biomedicine",

author = "Khan, {Nahid A.} and Mari Auranen and Ilse Paetau and Eija Pirinen and Liliya Euro and Saara Forsstr{\"o}m and Lotta Pasila and Vidya Velagapudi and Carroll, {Christopher J.} and Johan Auwerx and Anu Suomalainen",

year = "2014",

month = jun,

doi = "10.1002/emmm.201403943",

language = "English",

volume = "6",

pages = "721--731",

journal = "EMBO molecular medicine",

issn = "1757-4676",

publisher = "Springer Science and Business Media Deutschland GmbH",

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TY - JOUR

T1 - Effective treatment of mitochondrial myopathy by nicotinamide riboside, a vitamin B3

AU - Khan, Nahid A.

AU - Auranen, Mari

AU - Paetau, Ilse

AU - Pirinen, Eija

AU - Euro, Liliya

AU - Forsström, Saara

AU - Pasila, Lotta

AU - Velagapudi, Vidya

AU - Carroll, Christopher J.

AU - Auwerx, Johan

AU - Suomalainen, Anu

PY - 2014/6

Y1 - 2014/6

KW - mitochondrial myopathy

KW - NAD(+)

KW - nicotinamide riboside

KW - treatment

KW - unfolded protein response

KW - PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA

KW - UNFOLDED-PROTEIN RESPONSE

KW - MULTIPLE DELETIONS

KW - ACTIVATION

KW - LONGEVITY

KW - PGC-1-ALPHA

KW - DISEASE

KW - SIRT1

KW - DEACETYLASE

KW - 3111 Biomedicine

U2 - 10.1002/emmm.201403943

DO - 10.1002/emmm.201403943

M3 - Article

SN - 1757-4676

VL - 6

SP - 721

EP - 731

JO - EMBO molecular medicine

JF - EMBO molecular medicine

IS - 6

ER -

Effective treatment of mitochondrial myopathy by nicotinamide riboside, a vitamin B3

Fields of Science

Access to Document

Equipment

FIMM Metabolomics (LS-RIA/ Metabo-HiLIFE)

Cite this