Efficacy of broccoli and glucoraphanin in COVID-19: From hypothesis to proof-of-concept with three experimental clinical cases

Jean Bousquet; Vincent Le Moing; Hubert Blain; Wienczyslawa Czarlewski; Torsten Zuberbier; Raphael de la Torre; Nieves Pizarro Lozano; Jacques Reynes; Anna Bedbrook; Jean-Paul Cristol; Alvaro A. Cruz; Alessandro Fiocchi; Tari Haahtela; Guido Iaccarino; Ludger Klimek; Piotr Kuna; Erik Melén; Joaquim Mullol; Boleslaw Samolinski; Arunas Valiulis; Josep M. Anto

doi:10.1016/j.waojou.2020.100498

Efficacy of broccoli and glucoraphanin in COVID-19: From hypothesis to proof-of-concept with three experimental clinical cases

Jean Bousquet, Vincent Le Moing, Hubert Blain, Wienczyslawa Czarlewski, Torsten Zuberbier, Raphael de la Torre, Nieves Pizarro Lozano, Jacques Reynes, Anna Bedbrook, Jean-Paul Cristol, Alvaro A. Cruz, Alessandro Fiocchi, Tari Haahtela, Guido Iaccarino, Ludger Klimek, Piotr Kuna, Erik Melén, Joaquim Mullol, Boleslaw Samolinski, Arunas ValiulisJosep M. Anto

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	100498
Journal	World Allergy Organization journal
Volume	14
Issue number	1
Number of pages	16
ISSN	1939-4551
DOIs	https://doi.org/10.1016/j.waojou.2020.100498
Publication status	Published - Jan 2021
MoE publication type	A1 Journal article-refereed

Fields of Science

3121 General medicine, internal medicine and other clinical medicine
COVID-19
Nrf2
broccoli
cough challenge
TRPA1
TRPV1
ACTIVATION
MECHANISM
SULFORAPHANE
STRATEGY
CHEMOPREVENTION
INDUCED CARDIOMYOPATHY
Cough challenge
RHINITIS
Broccoli
NRF2
RICH
COUGH

Access to Document

10.1016/j.waojou.2020.100498

1-s2.0-S1939455120304014-mainFinal published version, 1.42 MBLicence: CC BY

Cite this

Bousquet, J., Le Moing, V., Blain, H., Czarlewski, W., Zuberbier, T., Torre, R. D. L., Lozano, N. P., Reynes, J., Bedbrook, A., Cristol, J-P., Cruz, A. A., Fiocchi, A., Haahtela, T., Iaccarino, G., Klimek, L., Kuna, P., Melén, E., Mullol, J., Samolinski, B., ... Anto, J. M. (2021). Efficacy of broccoli and glucoraphanin in COVID-19: From hypothesis to proof-of-concept with three experimental clinical cases. World Allergy Organization journal, 14(1), [100498]. https://doi.org/10.1016/j.waojou.2020.100498

Bousquet, Jean ; Le Moing, Vincent ; Blain, Hubert ; Czarlewski, Wienczyslawa ; Zuberbier, Torsten ; Torre, Raphael de la ; Lozano, Nieves Pizarro ; Reynes, Jacques ; Bedbrook, Anna ; Cristol, Jean-Paul ; Cruz, Alvaro A. ; Fiocchi, Alessandro ; Haahtela, Tari ; Iaccarino, Guido ; Klimek, Ludger ; Kuna, Piotr ; Melén, Erik ; Mullol, Joaquim ; Samolinski, Boleslaw ; Valiulis, Arunas ; Anto, Josep M. / Efficacy of broccoli and glucoraphanin in COVID-19: From hypothesis to proof-of-concept with three experimental clinical cases. In: World Allergy Organization journal. 2021 ; Vol. 14, No. 1.

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title = "Efficacy of broccoli and glucoraphanin in COVID-19: From hypothesis to proof-of-concept with three experimental clinical cases",

keywords = "3121 General medicine, internal medicine and other clinical medicine, COVID-19, Nrf2, broccoli, cough challenge, TRPA1, TRPV1, ACTIVATION, MECHANISM, SULFORAPHANE, STRATEGY, CHEMOPREVENTION, INDUCED CARDIOMYOPATHY, Cough challenge, RHINITIS, Broccoli, NRF2, RICH, COUGH",

author = "Jean Bousquet and {Le Moing}, Vincent and Hubert Blain and Wienczyslawa Czarlewski and Torsten Zuberbier and Torre, {Raphael de la} and Lozano, {Nieves Pizarro} and Jacques Reynes and Anna Bedbrook and Jean-Paul Cristol and Cruz, {Alvaro A.} and Alessandro Fiocchi and Tari Haahtela and Guido Iaccarino and Ludger Klimek and Piotr Kuna and Erik Mel{\'e}n and Joaquim Mullol and Boleslaw Samolinski and Arunas Valiulis and Anto, {Josep M.}",

year = "2021",

month = jan,

doi = "10.1016/j.waojou.2020.100498",

language = "English",

volume = "14",

journal = "World Allergy Organization journal",

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Bousquet, J, Le Moing, V, Blain, H, Czarlewski, W, Zuberbier, T, Torre, RDL, Lozano, NP, Reynes, J, Bedbrook, A, Cristol, J-P, Cruz, AA, Fiocchi, A, Haahtela, T, Iaccarino, G, Klimek, L, Kuna, P, Melén, E, Mullol, J, Samolinski, B, Valiulis, A & Anto, JM 2021, 'Efficacy of broccoli and glucoraphanin in COVID-19: From hypothesis to proof-of-concept with three experimental clinical cases', World Allergy Organization journal, vol. 14, no. 1, 100498. https://doi.org/10.1016/j.waojou.2020.100498

Efficacy of broccoli and glucoraphanin in COVID-19: From hypothesis to proof-of-concept with three experimental clinical cases. / Bousquet, Jean; Le Moing, Vincent; Blain, Hubert; Czarlewski, Wienczyslawa; Zuberbier, Torsten; Torre, Raphael de la; Lozano, Nieves Pizarro; Reynes, Jacques; Bedbrook, Anna; Cristol, Jean-Paul; Cruz, Alvaro A.; Fiocchi, Alessandro; Haahtela, Tari; Iaccarino, Guido; Klimek, Ludger; Kuna, Piotr; Melén, Erik; Mullol, Joaquim; Samolinski, Boleslaw; Valiulis, Arunas; Anto, Josep M.

In: World Allergy Organization journal, Vol. 14, No. 1, 100498, 01.2021.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - Efficacy of broccoli and glucoraphanin in COVID-19: From hypothesis to proof-of-concept with three experimental clinical cases

AU - Bousquet, Jean

AU - Le Moing, Vincent

AU - Blain, Hubert

AU - Czarlewski, Wienczyslawa

AU - Zuberbier, Torsten

AU - Torre, Raphael de la

AU - Lozano, Nieves Pizarro

AU - Reynes, Jacques

AU - Bedbrook, Anna

AU - Cristol, Jean-Paul

AU - Cruz, Alvaro A.

AU - Fiocchi, Alessandro

AU - Haahtela, Tari

AU - Iaccarino, Guido

AU - Klimek, Ludger

AU - Kuna, Piotr

AU - Melén, Erik

AU - Mullol, Joaquim

AU - Samolinski, Boleslaw

AU - Valiulis, Arunas

AU - Anto, Josep M.

PY - 2021/1

Y1 - 2021/1

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KW - COVID-19

KW - Nrf2

KW - broccoli

KW - cough challenge

KW - TRPA1

KW - TRPV1

KW - ACTIVATION

KW - MECHANISM

KW - SULFORAPHANE

KW - STRATEGY

KW - CHEMOPREVENTION

KW - INDUCED CARDIOMYOPATHY

KW - Cough challenge

KW - RHINITIS

KW - Broccoli

KW - NRF2

KW - RICH

KW - COUGH

U2 - 10.1016/j.waojou.2020.100498

DO - 10.1016/j.waojou.2020.100498

M3 - Article

VL - 14

JO - World Allergy Organization journal

JF - World Allergy Organization journal

SN - 1939-4551

IS - 1

M1 - 100498

ER -