Efficient Inhibition of Avian and Seasonal Influenza A Viruses by a Virus-Specific Dicer-Substrate Small Interfering RNA Swarm in Human Monocyte-Derived Macrophages and Dendritic Cells

Miao Jiang, Pamela Osterlund, Veera Westenius, Deyin Guo, Minna M. Poranen, Dennis H. Bamford, Ilkka Julkunen

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
Article number01916
JournalJournal of Virology
Volume93
Issue number4
Number of pages21
ISSN0022-538X
DOIs
Publication statusPublished - Feb 2019
MoE publication typeA1 Journal article-refereed

Fields of Science

  • Dicer-substrate siRNA
  • DsiRNA
  • RNA interference
  • avian influenza virus
  • gene silencing
  • human macrophage
  • human moDC
  • influenza A virus
  • IAV
  • interferon response
  • IFN
  • siRNA swarm
  • viral replication
  • IN-VITRO
  • PANDEMIC INFLUENZA
  • PROTEIN EXPRESSION
  • SIRNA POOLS
  • IFN-ALPHA
  • REPLICATION
  • INFECTION
  • RECOGNITION
  • INDUCTION
  • PROTECTION
  • 1183 Plant biology, microbiology, virology

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