EGFR gene copy number decreases during anti-EGFR antibody therapy in colorectal cancer

Eva-Maria Birkman, Tuulia Avoranta, Annika Algars, Eija Korkeila, Minnamaija Lintunen, Laura Lahtinen, Teijo Kuopio, Raija Ristamäki, Olli Carpen, Jari Sundström

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalHuman Pathology
Volume82
Pages (from-to)163-171
Number of pages9
ISSN0046-8177
DOIs
Publication statusPublished - Dec 2018
MoE publication typeA1 Journal article-refereed

Fields of Science

  • Colorectal cancer
  • Epidermal growth factor receptor
  • Gene copy number
  • Silver in situ hybridization
  • Monoclonal antibody
  • ACQUIRED-RESISTANCE
  • CETUXIMAB THERAPY
  • PREDICTS RESPONSE
  • RAS MUTATIONS
  • WILD-TYPE
  • KRAS
  • HETEROGENEITY
  • METAANALYSIS
  • BLOCKADE
  • BENEFIT
  • 3111 Biomedicine
  • 3122 Cancers

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