Elevated serum chemokine CCL22 levels in first-episode psychosis: associations with symptoms, peripheral immune state and in vivo brain glial cell function

Heikki Laurikainen; Arja Vuorela; Anna Toivonen; Linnea Reinert-Hartwall; Kalevi Trontti; Maija Lindgren; Jaakko Keinanen; Teemu Mäntylä; Janina Paju; Tuula Ilonen; Reetta-Liina Armio; Maija Walta; Jouni Tuisku; Semi Helin; Päivi Marjamäki; Iiris Hovatta; Sebastian Therman; Outi Vaarala; Outi Linnaranta; Tuula Kieseppä; Raimo K. R. Salokangas; Jarno Honkanen; Jarmo Hietala; Jaana Suvisaari

doi:10.1038/s41398-020-0776-z

Elevated serum chemokine CCL22 levels in first-episode psychosis: associations with symptoms, peripheral immune state and in vivo brain glial cell function

Heikki Laurikainen, Arja Vuorela, Anna Toivonen, Linnea Reinert-Hartwall, Kalevi Trontti, Maija Lindgren, Jaakko Keinanen, Teemu Mäntylä, Janina Paju, Tuula Ilonen, Reetta-Liina Armio, Maija Walta, Jouni Tuisku, Semi Helin, Päivi Marjamäki, Iiris Hovatta, Sebastian Therman, Outi Vaarala, Outi Linnaranta, Tuula KieseppäRaimo K. R. Salokangas, Jarno Honkanen, Jarmo Hietala, Jaana Suvisaari

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	94
Journal	Translational Psychiatry
Volume	10
Issue number	1
Number of pages	14
ISSN	2158-3188
DOIs	https://doi.org/10.1038/s41398-020-0776-z
Publication status	Published - 16 Mar 2020
MoE publication type	A1 Journal article-refereed

Fields of Science

PROTEIN 18 KDA
EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS
MACROPHAGE-DERIVED CHEMOKINE
TRANSLOCATOR PROTEIN
BENZODIAZEPINE-RECEPTOR
SCHIZOPHRENIA
MICROGLIA
CYTOKINES
TSPO
RADIOLIGAND
3124 Neurology and psychiatry

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10.1038/s41398-020-0776-z

s41398-020-0776-zFinal published version, 5.16 MBLicence: CC BY

Cite this

Laurikainen, H., Vuorela, A., Toivonen, A., Reinert-Hartwall, L., Trontti, K., Lindgren, M., Keinanen, J., Mäntylä, T., Paju, J., Ilonen, T., Armio, R-L., Walta, M., Tuisku, J., Helin, S., Marjamäki, P., Hovatta, I., Therman, S., Vaarala, O., Linnaranta, O., ... Suvisaari, J. (2020). Elevated serum chemokine CCL22 levels in first-episode psychosis: associations with symptoms, peripheral immune state and in vivo brain glial cell function. Translational Psychiatry, 10(1), [94]. https://doi.org/10.1038/s41398-020-0776-z

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title = "Elevated serum chemokine CCL22 levels in first-episode psychosis: associations with symptoms, peripheral immune state and in vivo brain glial cell function",

keywords = "PROTEIN 18 KDA, EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS, MACROPHAGE-DERIVED CHEMOKINE, TRANSLOCATOR PROTEIN, BENZODIAZEPINE-RECEPTOR, SCHIZOPHRENIA, MICROGLIA, CYTOKINES, TSPO, RADIOLIGAND, 3124 Neurology and psychiatry",

author = "Heikki Laurikainen and Arja Vuorela and Anna Toivonen and Linnea Reinert-Hartwall and Kalevi Trontti and Maija Lindgren and Jaakko Keinanen and Teemu M{\"a}ntyl{\"a} and Janina Paju and Tuula Ilonen and Reetta-Liina Armio and Maija Walta and Jouni Tuisku and Semi Helin and P{\"a}ivi Marjam{\"a}ki and Iiris Hovatta and Sebastian Therman and Outi Vaarala and Outi Linnaranta and Tuula Kiesepp{\"a} and Salokangas, {Raimo K. R.} and Jarno Honkanen and Jarmo Hietala and Jaana Suvisaari",

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doi = "10.1038/s41398-020-0776-z",

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Laurikainen, H, Vuorela, A, Toivonen, A, Reinert-Hartwall, L, Trontti, K, Lindgren, M, Keinanen, J, Mäntylä, T, Paju, J, Ilonen, T, Armio, R-L, Walta, M, Tuisku, J, Helin, S, Marjamäki, P, Hovatta, I, Therman, S, Vaarala, O, Linnaranta, O, Kieseppä, T, Salokangas, RKR, Honkanen, J, Hietala, J & Suvisaari, J 2020, 'Elevated serum chemokine CCL22 levels in first-episode psychosis: associations with symptoms, peripheral immune state and in vivo brain glial cell function', Translational Psychiatry, vol. 10, no. 1, 94. https://doi.org/10.1038/s41398-020-0776-z

TY - JOUR

T1 - Elevated serum chemokine CCL22 levels in first-episode psychosis

T2 - associations with symptoms, peripheral immune state and in vivo brain glial cell function

AU - Laurikainen, Heikki

AU - Vuorela, Arja

AU - Toivonen, Anna

AU - Reinert-Hartwall, Linnea

AU - Trontti, Kalevi

AU - Lindgren, Maija

AU - Keinanen, Jaakko

AU - Mäntylä, Teemu

AU - Paju, Janina

AU - Ilonen, Tuula

AU - Armio, Reetta-Liina

AU - Walta, Maija

AU - Tuisku, Jouni

AU - Helin, Semi

AU - Marjamäki, Päivi

AU - Hovatta, Iiris

AU - Therman, Sebastian

AU - Vaarala, Outi

AU - Linnaranta, Outi

AU - Kieseppä, Tuula

AU - Salokangas, Raimo K. R.

AU - Honkanen, Jarno

AU - Hietala, Jarmo

AU - Suvisaari, Jaana

PY - 2020/3/16

Y1 - 2020/3/16

KW - PROTEIN 18 KDA

KW - EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS

KW - MACROPHAGE-DERIVED CHEMOKINE

KW - TRANSLOCATOR PROTEIN

KW - BENZODIAZEPINE-RECEPTOR

KW - SCHIZOPHRENIA

KW - MICROGLIA

KW - CYTOKINES

KW - TSPO

KW - RADIOLIGAND

KW - 3124 Neurology and psychiatry

U2 - 10.1038/s41398-020-0776-z

DO - 10.1038/s41398-020-0776-z

M3 - Article

VL - 10

JO - Translational Psychiatry

JF - Translational Psychiatry

SN - 2158-3188

IS - 1

M1 - 94

ER -