Elevated TLR5 expression in vivo and loss of NF-kappa B activation via TLR5 in vitro detected in HPV-negative oropharyngeal squamous cell carcinoma

Anna Kaisa Kylmä; Tuomas Aleksi Tolvanen; Timo Carpén; Caj Haglund; Antti Mäkitie; Petri S. Mattila; Reidar Grenman; Lauri Jouhi; Timo Sorsa; Sanna Lehtonen; Jaana Hagström

doi:10.1016/j.yexmp.2020.104435

Elevated TLR5 expression in vivo and loss of NF-kappa B activation via TLR5 in vitro detected in HPV-negative oropharyngeal squamous cell carcinoma

Anna Kaisa Kylmä, Tuomas Aleksi Tolvanen, Timo Carpén, Caj Haglund, Antti Mäkitie, Petri S. Mattila, Reidar Grenman, Lauri Jouhi, Timo Sorsa, Sanna Lehtonen, Jaana Hagström

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	104435
Journal	Experimental and Molecular Pathology
Volume	114
Number of pages	9
ISSN	0014-4800
DOIs	https://doi.org/10.1016/j.yexmp.2020.104435
Publication status	Published - Jun 2020
MoE publication type	A1 Journal article-refereed

Fields of Science

3111 Biomedicine
Oropharyngeal squamous cell carcinoma
Human papillomavirus
Toll-like receptor
Nuclear factor-κΒ
Nuclear factor-kappa B
CANCER-CELLS
KINASE-ALPHA
SURVIVAL
PROLIFERATION
HUMAN-PAPILLOMAVIRUS
MESENCHYMAL TRANSITION
INTERACTING PROTEIN
INFLAMMATION
TOLL-LIKE RECEPTORS
TNF-ALPHA

Access to Document

10.1016/j.yexmp.2020.104435

1-s2.0-S0014480019304198-mainAccepted author manuscript, 0.98 MBLicence: CC BY-NC-ND

Cite this

Kylmä, A. K., Tolvanen, T. A., Carpén, T., Haglund, C., Mäkitie, A., Mattila, P. S., Grenman, R., Jouhi, L., Sorsa, T., Lehtonen, S., & Hagström, J. (2020). Elevated TLR5 expression in vivo and loss of NF-kappa B activation via TLR5 in vitro detected in HPV-negative oropharyngeal squamous cell carcinoma. Experimental and Molecular Pathology, 114, [104435]. https://doi.org/10.1016/j.yexmp.2020.104435

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title = "Elevated TLR5 expression in vivo and loss of NF-kappa B activation via TLR5 in vitro detected in HPV-negative oropharyngeal squamous cell carcinoma",

keywords = "3111 Biomedicine, Oropharyngeal squamous cell carcinoma, Human papillomavirus, Toll-like receptor, Nuclear factor-κΒ, Nuclear factor-kappa B, CANCER-CELLS, KINASE-ALPHA, SURVIVAL, PROLIFERATION, HUMAN-PAPILLOMAVIRUS, MESENCHYMAL TRANSITION, INTERACTING PROTEIN, INFLAMMATION, TOLL-LIKE RECEPTORS, TNF-ALPHA",

author = "Kylm{\"a}, {Anna Kaisa} and Tolvanen, {Tuomas Aleksi} and Timo Carp{\'e}n and Caj Haglund and Antti M{\"a}kitie and Mattila, {Petri S.} and Reidar Grenman and Lauri Jouhi and Timo Sorsa and Sanna Lehtonen and Jaana Hagstr{\"o}m",

year = "2020",

month = jun,

doi = "10.1016/j.yexmp.2020.104435",

language = "English",

volume = "114",

journal = "Experimental and Molecular Pathology",

issn = "0014-4800",

publisher = "ACADEMIC PRESS INC ELSEVIER SCIENCE",

}

Kylmä, AK, Tolvanen, TA, Carpén, T, Haglund, C , Mäkitie, A , Mattila, PS, Grenman, R, Jouhi, L , Sorsa, T , Lehtonen, S & Hagström, J 2020, 'Elevated TLR5 expression in vivo and loss of NF-kappa B activation via TLR5 in vitro detected in HPV-negative oropharyngeal squamous cell carcinoma', Experimental and Molecular Pathology, vol. 114, 104435. https://doi.org/10.1016/j.yexmp.2020.104435

TY - JOUR

T1 - Elevated TLR5 expression in vivo and loss of NF-kappa B activation via TLR5 in vitro detected in HPV-negative oropharyngeal squamous cell carcinoma

AU - Kylmä, Anna Kaisa

AU - Tolvanen, Tuomas Aleksi

AU - Carpén, Timo

AU - Haglund, Caj

AU - Mäkitie, Antti

AU - Mattila, Petri S.

AU - Grenman, Reidar

AU - Jouhi, Lauri

AU - Sorsa, Timo

AU - Lehtonen, Sanna

AU - Hagström, Jaana

PY - 2020/6

Y1 - 2020/6

KW - 3111 Biomedicine

KW - Oropharyngeal squamous cell carcinoma

KW - Human papillomavirus

KW - Toll-like receptor

KW - Nuclear factor-κΒ

KW - Nuclear factor-kappa B

KW - CANCER-CELLS

KW - KINASE-ALPHA

KW - SURVIVAL

KW - PROLIFERATION

KW - HUMAN-PAPILLOMAVIRUS

KW - MESENCHYMAL TRANSITION

KW - INTERACTING PROTEIN

KW - INFLAMMATION

KW - TOLL-LIKE RECEPTORS

KW - TNF-ALPHA

U2 - 10.1016/j.yexmp.2020.104435

DO - 10.1016/j.yexmp.2020.104435

M3 - Article

VL - 114

JO - Experimental and Molecular Pathology

JF - Experimental and Molecular Pathology

SN - 0014-4800

M1 - 104435

ER -