Enrichment of low-frequency functional variants revealed by whole-genome sequencing of multiple isolated European populations

Yali Xue, Massimo Mezzavilla, Marc Haber, Shane McCarthy, Yuan Chen, Vagheesh Narasimhan, Arthur Gilly, Qasim Ayub, Vincenza Colonna, Lorraine Southam, Christopher Finan, Andrea Massaia, Himanshu Chheda, Priit Palta, Graham Ritchie, Jennifer Asimit, George Dedoussis, Paolo Gasparini, Aarno Palotie, Samuli Ripatti & 6 others Nicole Soranzo, Daniela Toniolo, James F. Wilson, Richard Durbin, Chris Tyler-Smith, Eleftheria Zeggini

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
Article number15927
JournalNature Communications
Volume8
Number of pages7
ISSN2041-1723
DOIs
Publication statusPublished - 23 Jun 2017
MoE publication typeA1 Journal article-refereed

Fields of Science

  • LINKAGE DISEQUILIBRIUM
  • GENETIC-CHARACTERIZATION
  • RARE VARIANT
  • SIZE
  • ASSOCIATION
  • INDIVIDUALS
  • ADAPTATION
  • SELECTION
  • IDENTITY
  • DESCENT
  • 3111 Biomedicine

Cite this

Xue, Yali ; Mezzavilla, Massimo ; Haber, Marc ; McCarthy, Shane ; Chen, Yuan ; Narasimhan, Vagheesh ; Gilly, Arthur ; Ayub, Qasim ; Colonna, Vincenza ; Southam, Lorraine ; Finan, Christopher ; Massaia, Andrea ; Chheda, Himanshu ; Palta, Priit ; Ritchie, Graham ; Asimit, Jennifer ; Dedoussis, George ; Gasparini, Paolo ; Palotie, Aarno ; Ripatti, Samuli ; Soranzo, Nicole ; Toniolo, Daniela ; Wilson, James F. ; Durbin, Richard ; Tyler-Smith, Chris ; Zeggini, Eleftheria. / Enrichment of low-frequency functional variants revealed by whole-genome sequencing of multiple isolated European populations. In: Nature Communications. 2017 ; Vol. 8.
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title = "Enrichment of low-frequency functional variants revealed by whole-genome sequencing of multiple isolated European populations",
keywords = "LINKAGE DISEQUILIBRIUM, GENETIC-CHARACTERIZATION, RARE VARIANT, SIZE, ASSOCIATION, INDIVIDUALS, ADAPTATION, SELECTION, IDENTITY, DESCENT, 3111 Biomedicine",
author = "Yali Xue and Massimo Mezzavilla and Marc Haber and Shane McCarthy and Yuan Chen and Vagheesh Narasimhan and Arthur Gilly and Qasim Ayub and Vincenza Colonna and Lorraine Southam and Christopher Finan and Andrea Massaia and Himanshu Chheda and Priit Palta and Graham Ritchie and Jennifer Asimit and George Dedoussis and Paolo Gasparini and Aarno Palotie and Samuli Ripatti and Nicole Soranzo and Daniela Toniolo and Wilson, {James F.} and Richard Durbin and Chris Tyler-Smith and Eleftheria Zeggini",
year = "2017",
month = "6",
day = "23",
doi = "10.1038/ncomms15927",
language = "English",
volume = "8",
journal = "Nature Communications",
issn = "2041-1723",
publisher = "Nature Publishing Group",

}

Xue, Y, Mezzavilla, M, Haber, M, McCarthy, S, Chen, Y, Narasimhan, V, Gilly, A, Ayub, Q, Colonna, V, Southam, L, Finan, C, Massaia, A, Chheda, H, Palta, P, Ritchie, G, Asimit, J, Dedoussis, G, Gasparini, P, Palotie, A, Ripatti, S, Soranzo, N, Toniolo, D, Wilson, JF, Durbin, R, Tyler-Smith, C & Zeggini, E 2017, 'Enrichment of low-frequency functional variants revealed by whole-genome sequencing of multiple isolated European populations', Nature Communications, vol. 8, 15927. https://doi.org/10.1038/ncomms15927

Enrichment of low-frequency functional variants revealed by whole-genome sequencing of multiple isolated European populations. / Xue, Yali; Mezzavilla, Massimo; Haber, Marc; McCarthy, Shane; Chen, Yuan; Narasimhan, Vagheesh; Gilly, Arthur; Ayub, Qasim; Colonna, Vincenza; Southam, Lorraine; Finan, Christopher; Massaia, Andrea; Chheda, Himanshu; Palta, Priit; Ritchie, Graham; Asimit, Jennifer; Dedoussis, George; Gasparini, Paolo; Palotie, Aarno; Ripatti, Samuli; Soranzo, Nicole; Toniolo, Daniela; Wilson, James F.; Durbin, Richard; Tyler-Smith, Chris; Zeggini, Eleftheria.

In: Nature Communications, Vol. 8, 15927, 23.06.2017.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Enrichment of low-frequency functional variants revealed by whole-genome sequencing of multiple isolated European populations

AU - Xue, Yali

AU - Mezzavilla, Massimo

AU - Haber, Marc

AU - McCarthy, Shane

AU - Chen, Yuan

AU - Narasimhan, Vagheesh

AU - Gilly, Arthur

AU - Ayub, Qasim

AU - Colonna, Vincenza

AU - Southam, Lorraine

AU - Finan, Christopher

AU - Massaia, Andrea

AU - Chheda, Himanshu

AU - Palta, Priit

AU - Ritchie, Graham

AU - Asimit, Jennifer

AU - Dedoussis, George

AU - Gasparini, Paolo

AU - Palotie, Aarno

AU - Ripatti, Samuli

AU - Soranzo, Nicole

AU - Toniolo, Daniela

AU - Wilson, James F.

AU - Durbin, Richard

AU - Tyler-Smith, Chris

AU - Zeggini, Eleftheria

PY - 2017/6/23

Y1 - 2017/6/23

KW - LINKAGE DISEQUILIBRIUM

KW - GENETIC-CHARACTERIZATION

KW - RARE VARIANT

KW - SIZE

KW - ASSOCIATION

KW - INDIVIDUALS

KW - ADAPTATION

KW - SELECTION

KW - IDENTITY

KW - DESCENT

KW - 3111 Biomedicine

U2 - 10.1038/ncomms15927

DO - 10.1038/ncomms15927

M3 - Article

VL - 8

JO - Nature Communications

JF - Nature Communications

SN - 2041-1723

M1 - 15927

ER -