Epigenetic Reprogramming Sensitizes CML Stem Cells to Combined EZH2 and Tyrosine Kinase Inhibition

Mary T. Scott, Koorosh Korfi, Peter Saffrey, Lisa E. M. Hopcroft, Ross Kinstrie, Francesca Pellicano, Carla Guenther, Paolo Gallipoli, Michelle Cruz, Karen Dunn, Heather G. Jorgensen, Jennifer E. Cassels, Ashley Hamilton, Andrew Crossan, Amy Sinclair, Tessa L. Holyoake, David Vetrie

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalCancer Discovery
Volume6
Issue number11
Pages (from-to)1248-1257
Number of pages10
ISSN2159-8274
DOIs
Publication statusPublished - Nov 2016
Externally publishedYes
MoE publication typeA1 Journal article-refereed

Fields of Science

  • CHRONIC MYELOID-LEUKEMIA
  • METHYLTRANSFERASE EZH2
  • RESIDUAL DISEASE
  • IMATINIB
  • PERSISTENCE
  • EXPRESSION
  • SURVIVAL
  • POTENT
  • 3122 Cancers
  • 1182 Biochemistry, cell and molecular biology

Cite this