Equine infectious keratitis in Finland: Associated microbial isolates and susceptibility profiles

Research output: Contribution to journalArticleScientificpeer-review

Abstract

Abstract Objective To retrospectively describe laboratory findings, treatment, and outcome associated with equine infectious keratitis in Finland. Animals and procedures Medical records of horses diagnosed with infectious keratitis in University of Helsinki Equine Hospital from January 2007 to June 2018 were reviewed. Results Forty-seven cases were included. Keratomycosis was diagnosed in 27 eyes and bacterial keratitis in 20 eyes. Aspergillus flavus was the most frequent fungal isolate (9/17, 53%), followed by Cylindrocarpon sp. (3/17, 18%) and Aspergillus fumigatus (2/17, 12%). Susceptibility was tested for 10/11 Aspergillus sp. isolates; all were susceptible to voriconazole while only two were susceptible to amphotericin B. Cylindrocarpon sp. isolates were resistant to both agents. Streptococcus equi subsp. zooepidemicus was the most frequent bacterial isolate (9/19, 47%), followed by other streptococci (4/19, 21%). All 13 Streptococcus sp. isolates were susceptible to penicillin, and all tested isolates (n = 11) were also susceptible to chloramphenicol. Mean duration of medical treatment was longer in fungal keratitis (38 days) than in bacterial keratitis (25 days) (P 
Original languageFinnish
JournalVeterinary Ophthalmology
ISSN1463-5216
DOIs
Publication statusPublished - 31 Jul 2019
MoE publication typeA1 Journal article-refereed

Fields of Science

  • 412 Animal science, dairy science

Cite this

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title = "Equine infectious keratitis in Finland: Associated microbial isolates and susceptibility profiles",
abstract = "Abstract Objective To retrospectively describe laboratory findings, treatment, and outcome associated with equine infectious keratitis in Finland. Animals and procedures Medical records of horses diagnosed with infectious keratitis in University of Helsinki Equine Hospital from January 2007 to June 2018 were reviewed. Results Forty-seven cases were included. Keratomycosis was diagnosed in 27 eyes and bacterial keratitis in 20 eyes. Aspergillus flavus was the most frequent fungal isolate (9/17, 53{\%}), followed by Cylindrocarpon sp. (3/17, 18{\%}) and Aspergillus fumigatus (2/17, 12{\%}). Susceptibility was tested for 10/11 Aspergillus sp. isolates; all were susceptible to voriconazole while only two were susceptible to amphotericin B. Cylindrocarpon sp. isolates were resistant to both agents. Streptococcus equi subsp. zooepidemicus was the most frequent bacterial isolate (9/19, 47{\%}), followed by other streptococci (4/19, 21{\%}). All 13 Streptococcus sp. isolates were susceptible to penicillin, and all tested isolates (n = 11) were also susceptible to chloramphenicol. Mean duration of medical treatment was longer in fungal keratitis (38 days) than in bacterial keratitis (25 days) (P ",
keywords = "bacterial keratitis, cornea, equine, fungal keratitis, isolates, susceptibility, 412 Kotiel{\"a}intiede, maitotaloustiede",
author = "Mustikka, {Minna P.} and Gr{\"o}nthal, {Thomas S. C.} and Pietil{\"a}, {Elina M.}",
note = "doi: 10.1111/vop.12701",
year = "2019",
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day = "31",
doi = "10.1111/vop.12701",
language = "suomi",
journal = "Veterinary Ophthalmology",
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Equine infectious keratitis in Finland: Associated microbial isolates and susceptibility profiles. / Mustikka, Minna P.; Grönthal, Thomas S. C.; Pietilä, Elina M.

In: Veterinary Ophthalmology, 31.07.2019.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Equine infectious keratitis in Finland: Associated microbial isolates and susceptibility profiles

AU - Mustikka, Minna P.

AU - Grönthal, Thomas S. C.

AU - Pietilä, Elina M.

N1 - doi: 10.1111/vop.12701

PY - 2019/7/31

Y1 - 2019/7/31

N2 - Abstract Objective To retrospectively describe laboratory findings, treatment, and outcome associated with equine infectious keratitis in Finland. Animals and procedures Medical records of horses diagnosed with infectious keratitis in University of Helsinki Equine Hospital from January 2007 to June 2018 were reviewed. Results Forty-seven cases were included. Keratomycosis was diagnosed in 27 eyes and bacterial keratitis in 20 eyes. Aspergillus flavus was the most frequent fungal isolate (9/17, 53%), followed by Cylindrocarpon sp. (3/17, 18%) and Aspergillus fumigatus (2/17, 12%). Susceptibility was tested for 10/11 Aspergillus sp. isolates; all were susceptible to voriconazole while only two were susceptible to amphotericin B. Cylindrocarpon sp. isolates were resistant to both agents. Streptococcus equi subsp. zooepidemicus was the most frequent bacterial isolate (9/19, 47%), followed by other streptococci (4/19, 21%). All 13 Streptococcus sp. isolates were susceptible to penicillin, and all tested isolates (n = 11) were also susceptible to chloramphenicol. Mean duration of medical treatment was longer in fungal keratitis (38 days) than in bacterial keratitis (25 days) (P 

AB - Abstract Objective To retrospectively describe laboratory findings, treatment, and outcome associated with equine infectious keratitis in Finland. Animals and procedures Medical records of horses diagnosed with infectious keratitis in University of Helsinki Equine Hospital from January 2007 to June 2018 were reviewed. Results Forty-seven cases were included. Keratomycosis was diagnosed in 27 eyes and bacterial keratitis in 20 eyes. Aspergillus flavus was the most frequent fungal isolate (9/17, 53%), followed by Cylindrocarpon sp. (3/17, 18%) and Aspergillus fumigatus (2/17, 12%). Susceptibility was tested for 10/11 Aspergillus sp. isolates; all were susceptible to voriconazole while only two were susceptible to amphotericin B. Cylindrocarpon sp. isolates were resistant to both agents. Streptococcus equi subsp. zooepidemicus was the most frequent bacterial isolate (9/19, 47%), followed by other streptococci (4/19, 21%). All 13 Streptococcus sp. isolates were susceptible to penicillin, and all tested isolates (n = 11) were also susceptible to chloramphenicol. Mean duration of medical treatment was longer in fungal keratitis (38 days) than in bacterial keratitis (25 days) (P 

KW - bacterial keratitis

KW - cornea

KW - equine

KW - fungal keratitis

KW - isolates

KW - susceptibility

KW - 412 Kotieläintiede, maitotaloustiede

U2 - 10.1111/vop.12701

DO - 10.1111/vop.12701

M3 - Artikkeli

JO - Veterinary Ophthalmology

JF - Veterinary Ophthalmology

SN - 1463-5216

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