Estimate at your peril: Imputation methods for patient withdrawal can bias efficacy outcomes in chronic pain trials using responder analyses

R. Andrew Moore; Sebastian Straube; Christopher Eccleston; Sheena Derry; Dominic Aldington; Philip Wiffen; Rae F. Bell; Katri Hamunen; Ceri Phillips; Henry McQuay

doi:10.1016/j.pain.2011.10.004

Estimate at your peril: Imputation methods for patient withdrawal can bias efficacy outcomes in chronic pain trials using responder analyses

R. Andrew Moore, Sebastian Straube, Christopher Eccleston, Sheena Derry, Dominic Aldington, Philip Wiffen, Rae F. Bell, Katri Hamunen, Ceri Phillips, Henry McQuay

Research output: Contribution to journal › Review Article › peer-review

Original language	English
Journal	Pain
Volume	153
Issue number	2
Pages (from-to)	265-268
Number of pages	4
ISSN	0304-3959
DOIs	https://doi.org/10.1016/j.pain.2011.10.004
Publication status	Published - Feb 2012
MoE publication type	A2 Review article in a scientific journal

Fields of Science

CONTROLLED PHASE-III
LOW-BACK-PAIN
CLINICAL-TRIALS
DOUBLE-BLIND
MISSING DATA
RHEUMATOID-ARTHRITIS
EXTENDED-RELEASE
OSTEOARTHRITIS
FIBROMYALGIA
METAANALYSIS
3126 Surgery, anesthesiology, intensive care, radiology

Access to Document

10.1016/j.pain.2011.10.004

Cite this

@article{2e0b3d6d563d43408d89ec2701158bdc,

title = "Estimate at your peril: Imputation methods for patient withdrawal can bias efficacy outcomes in chronic pain trials using responder analyses",

keywords = "CONTROLLED PHASE-III, LOW-BACK-PAIN, CLINICAL-TRIALS, DOUBLE-BLIND, MISSING DATA, RHEUMATOID-ARTHRITIS, EXTENDED-RELEASE, OSTEOARTHRITIS, FIBROMYALGIA, METAANALYSIS, 3126 Surgery, anesthesiology, intensive care, radiology",

author = "Moore, {R. Andrew} and Sebastian Straube and Christopher Eccleston and Sheena Derry and Dominic Aldington and Philip Wiffen and Bell, {Rae F.} and Katri Hamunen and Ceri Phillips and Henry McQuay",

year = "2012",

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doi = "10.1016/j.pain.2011.10.004",

language = "English",

volume = "153",

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journal = "Pain",

issn = "0304-3959",

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T1 - Estimate at your peril

T2 - Imputation methods for patient withdrawal can bias efficacy outcomes in chronic pain trials using responder analyses

AU - Moore, R. Andrew

AU - Straube, Sebastian

AU - Eccleston, Christopher

AU - Derry, Sheena

AU - Aldington, Dominic

AU - Wiffen, Philip

AU - Bell, Rae F.

AU - Hamunen, Katri

AU - Phillips, Ceri

AU - McQuay, Henry

PY - 2012/2

Y1 - 2012/2

KW - CONTROLLED PHASE-III

KW - LOW-BACK-PAIN

KW - CLINICAL-TRIALS

KW - DOUBLE-BLIND

KW - MISSING DATA

KW - RHEUMATOID-ARTHRITIS

KW - EXTENDED-RELEASE

KW - OSTEOARTHRITIS

KW - FIBROMYALGIA

KW - METAANALYSIS

KW - 3126 Surgery, anesthesiology, intensive care, radiology

U2 - 10.1016/j.pain.2011.10.004

DO - 10.1016/j.pain.2011.10.004

M3 - Review Article

SN - 0304-3959

VL - 153

SP - 265

EP - 268

JO - Pain

JF - Pain

IS - 2

ER -