Ex vivo intracoronary gene transfer of adeno-associated virus 2 leads to superior transduction over serotypes 8 and 9 in rat heart transplants

Alireza Raissadati, Janne J. Jokinen, Simo O. Syrjala, Mikko Antti Ilmari Keränen, Rainer Krebs, Raimo Tuuminen, Ralica Arnaudova, Eeva Rouvinen, Andrey Anisimov, Jarkko Soronen, Katri Pajusola, Kari Alitalo, Antti I. Nykänen, Karl Birger Lemström

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalTransplant International
Volume26
Issue number11
Pages (from-to)1126-1137
Number of pages12
ISSN0934-0874
DOIs
Publication statusPublished - Nov 2013
MoE publication typeA1 Journal article-refereed

Fields of Science

  • adeno-associated virus
  • cardiac transduction
  • heart transplantation
  • intracoronary delivery
  • rat
  • LONG-TERM EXPRESSION
  • IMMUNE-RESPONSES
  • FACTOR-IX
  • INTRACELLULAR TRAFFICKING
  • EFFICIENT TRANSDUCTION
  • MUSCULAR-DYSTROPHY
  • ALLOGRAFT SURVIVAL
  • CARDIAC ALLOGRAFTS
  • CHRONIC REJECTION
  • SERUM ANTIBODIES
  • 3111 Biomedicine

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