Exploring the mucoadhesive behavior of sucrose acetate isobutyrate: a novel excipient for oral delivery of biopharmaceuticals

Stine Harloff-Helleberg, Lies A. L. Fliervoet, Mathias Fano, Mechthild Schmitt, Maxim Antopolski, Arto Urtti, Hanne Morck Nielsen

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalDrug Delivery
Volume26
Issue number1
Pages (from-to)532-541
Number of pages10
ISSN1071-7544
DOIs
Publication statusPublished - 1 Jan 2019
MoE publication typeA1 Journal article-refereed

Fields of Science

  • Sucrose acetate isobutyrate
  • mucoadhesion
  • rheology
  • in vivo SPECT
  • CT
  • dynamic gastric model
  • biopharmaceuticals
  • oral drug delivery
  • insulin
  • Caco-2 cells
  • IN-VITRO MODELS
  • DRUG-DELIVERY
  • RHEOLOGICAL EVALUATION
  • VIVO EVALUATION
  • SYSTEM
  • SAIB
  • NANOPARTICLES
  • FORMULATION
  • METABOLISM
  • MIXTURES
  • 317 Pharmacy
  • 116 Chemical sciences

Cite this

Harloff-Helleberg, Stine ; Fliervoet, Lies A. L. ; Fano, Mathias ; Schmitt, Mechthild ; Antopolski, Maxim ; Urtti, Arto ; Nielsen, Hanne Morck. / Exploring the mucoadhesive behavior of sucrose acetate isobutyrate : a novel excipient for oral delivery of biopharmaceuticals. In: Drug Delivery. 2019 ; Vol. 26, No. 1. pp. 532-541.
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keywords = "Sucrose acetate isobutyrate, mucoadhesion, rheology, in vivo SPECT, CT, dynamic gastric model, biopharmaceuticals, oral drug delivery, insulin, Caco-2 cells, IN-VITRO MODELS, DRUG-DELIVERY, RHEOLOGICAL EVALUATION, VIVO EVALUATION, SYSTEM, SAIB, NANOPARTICLES, FORMULATION, METABOLISM, MIXTURES, 317 Pharmacy, 116 Chemical sciences",
author = "Stine Harloff-Helleberg and Fliervoet, {Lies A. L.} and Mathias Fano and Mechthild Schmitt and Maxim Antopolski and Arto Urtti and Nielsen, {Hanne Morck}",
year = "2019",
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volume = "26",
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Exploring the mucoadhesive behavior of sucrose acetate isobutyrate : a novel excipient for oral delivery of biopharmaceuticals. / Harloff-Helleberg, Stine; Fliervoet, Lies A. L.; Fano, Mathias; Schmitt, Mechthild; Antopolski, Maxim; Urtti, Arto; Nielsen, Hanne Morck.

In: Drug Delivery, Vol. 26, No. 1, 01.01.2019, p. 532-541.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Exploring the mucoadhesive behavior of sucrose acetate isobutyrate

T2 - a novel excipient for oral delivery of biopharmaceuticals

AU - Harloff-Helleberg, Stine

AU - Fliervoet, Lies A. L.

AU - Fano, Mathias

AU - Schmitt, Mechthild

AU - Antopolski, Maxim

AU - Urtti, Arto

AU - Nielsen, Hanne Morck

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KW - in vivo SPECT

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KW - dynamic gastric model

KW - biopharmaceuticals

KW - oral drug delivery

KW - insulin

KW - Caco-2 cells

KW - IN-VITRO MODELS

KW - DRUG-DELIVERY

KW - RHEOLOGICAL EVALUATION

KW - VIVO EVALUATION

KW - SYSTEM

KW - SAIB

KW - NANOPARTICLES

KW - FORMULATION

KW - METABOLISM

KW - MIXTURES

KW - 317 Pharmacy

KW - 116 Chemical sciences

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DO - 10.1080/10717544.2019.1606866

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JO - Drug Delivery

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