FGF21 is a biomarker for mitochondrial translation and mtDNA maintenance disorders

Jenni M. Lehtonen; Saara Forsstrom; Emanuela Bottani; Carlo Viscomi; Olivier R. Baris; Helena Isoniemi; Krister Hockerstedt; Pia Osterlund; Mikko Hurme; Juulia Jylhava; Sirpa Leppa; Ritva Markkula; Tiina Helio; Giuliana Mombelli; Johanna Uusimaa; Reijo Laaksonen; Hannu Laaksovirta; Mari Auranen; Massimo Zeviani; Jan Smeitink; Rudolf J. Wiesner; Kazuto Nakada; Pirjo Isohanni; Anu Suomalainen

doi:10.1212/WNL.0000000000003374

FGF21 is a biomarker for mitochondrial translation and mtDNA maintenance disorders

Jenni M. Lehtonen, Saara Forsstrom, Emanuela Bottani, Carlo Viscomi, Olivier R. Baris, Helena Isoniemi, Krister Hockerstedt, Pia Osterlund, Mikko Hurme, Juulia Jylhava, Sirpa Leppa, Ritva Markkula, Tiina Helio, Giuliana Mombelli, Johanna Uusimaa, Reijo Laaksonen, Hannu Laaksovirta, Mari Auranen, Massimo Zeviani, Jan SmeitinkRudolf J. Wiesner, Kazuto Nakada, Pirjo Isohanni, Anu Suomalainen

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Neurology
Volume	87
Issue number	22
Pages (from-to)	2290-2299
Number of pages	10
ISSN	0028-3878
DOIs	https://doi.org/10.1212/WNL.0000000000003374
Publication status	Published - 29 Nov 2016
MoE publication type	A1 Journal article-refereed

Fields of Science

GROWTH
MICE
DISEASE
DEFICIENCY
ACTIVATION
MUTATIONS
DELETIONS
MYOPATHY
TWINKLE
OBESITY
3124 Neurology and psychiatry
3111 Biomedicine

Access to Document

10.1212/WNL.0000000000003374

Cite this

Lehtonen, J. M., Forsstrom, S., Bottani, E., Viscomi, C., Baris, O. R., Isoniemi, H., Hockerstedt, K., Osterlund, P., Hurme, M., Jylhava, J., Leppa, S., Markkula, R., Helio, T., Mombelli, G., Uusimaa, J., Laaksonen, R., Laaksovirta, H., Auranen, M., Zeviani, M., ... Suomalainen, A. (2016). FGF21 is a biomarker for mitochondrial translation and mtDNA maintenance disorders. Neurology, 87(22), 2290-2299. https://doi.org/10.1212/WNL.0000000000003374

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title = "FGF21 is a biomarker for mitochondrial translation and mtDNA maintenance disorders",

keywords = "GROWTH, MICE, DISEASE, DEFICIENCY, ACTIVATION, MUTATIONS, DELETIONS, MYOPATHY, TWINKLE, OBESITY, 3124 Neurology and psychiatry, 3111 Biomedicine",

author = "Lehtonen, {Jenni M.} and Saara Forsstrom and Emanuela Bottani and Carlo Viscomi and Baris, {Olivier R.} and Helena Isoniemi and Krister Hockerstedt and Pia Osterlund and Mikko Hurme and Juulia Jylhava and Sirpa Leppa and Ritva Markkula and Tiina Helio and Giuliana Mombelli and Johanna Uusimaa and Reijo Laaksonen and Hannu Laaksovirta and Mari Auranen and Massimo Zeviani and Jan Smeitink and Wiesner, {Rudolf J.} and Kazuto Nakada and Pirjo Isohanni and Anu Suomalainen",

year = "2016",

month = nov,

day = "29",

doi = "10.1212/WNL.0000000000003374",

language = "English",

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pages = "2290--2299",

journal = "Neurology",

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Lehtonen, JM, Forsstrom, S, Bottani, E, Viscomi, C, Baris, OR, Isoniemi, H, Hockerstedt, K , Osterlund, P, Hurme, M, Jylhava, J, Leppa, S , Markkula, R , Helio, T, Mombelli, G, Uusimaa, J, Laaksonen, R, Laaksovirta, H , Auranen, M, Zeviani, M, Smeitink, J, Wiesner, RJ, Nakada, K, Isohanni, P & Suomalainen, A 2016, 'FGF21 is a biomarker for mitochondrial translation and mtDNA maintenance disorders', Neurology, vol. 87, no. 22, pp. 2290-2299. https://doi.org/10.1212/WNL.0000000000003374

TY - JOUR

T1 - FGF21 is a biomarker for mitochondrial translation and mtDNA maintenance disorders

AU - Lehtonen, Jenni M.

AU - Forsstrom, Saara

AU - Bottani, Emanuela

AU - Viscomi, Carlo

AU - Baris, Olivier R.

AU - Isoniemi, Helena

AU - Hockerstedt, Krister

AU - Osterlund, Pia

AU - Hurme, Mikko

AU - Jylhava, Juulia

AU - Leppa, Sirpa

AU - Markkula, Ritva

AU - Helio, Tiina

AU - Mombelli, Giuliana

AU - Uusimaa, Johanna

AU - Laaksonen, Reijo

AU - Laaksovirta, Hannu

AU - Auranen, Mari

AU - Zeviani, Massimo

AU - Smeitink, Jan

AU - Wiesner, Rudolf J.

AU - Nakada, Kazuto

AU - Isohanni, Pirjo

AU - Suomalainen, Anu

PY - 2016/11/29

Y1 - 2016/11/29

KW - GROWTH

KW - MICE

KW - DISEASE

KW - DEFICIENCY

KW - ACTIVATION

KW - MUTATIONS

KW - DELETIONS

KW - MYOPATHY

KW - TWINKLE

KW - OBESITY

KW - 3124 Neurology and psychiatry

KW - 3111 Biomedicine

U2 - 10.1212/WNL.0000000000003374

DO - 10.1212/WNL.0000000000003374

M3 - Article

VL - 87

SP - 2290

EP - 2299

JO - Neurology

JF - Neurology

SN - 0028-3878

IS - 22

ER -