Fibroblast Growth Factor 21 Drives Dynamics of Local and Systemic Stress Responses in Mitochondrial Myopathy with mtDNA Deletions

Saara Forsström; Christopher B. Jackson; Christopher J. Carroll; Mervi Kuronen; Eija Pirinen; Swagat Pradhan; Anastasiia Marmyleva; Mari Auranen; Iida-Marja Kleine; Nahid A. Khan; Anne Roivainen; Paivi Marjamäki; Heidi Liljenbäck; Liya Wang; Brendan J. Battersby; Uwe Richter; Vidya Velagapudi; Joni Nikkanen; Liliya Euro; Anu Suomalainen

doi:10.1016/j.cmet.2019.013.019

Fibroblast Growth Factor 21 Drives Dynamics of Local and Systemic Stress Responses in Mitochondrial Myopathy with mtDNA Deletions

Saara Forsström, Christopher B. Jackson, Christopher J. Carroll, Mervi Kuronen, Eija Pirinen, Swagat Pradhan, Anastasiia Marmyleva, Mari Auranen, Iida-Marja Kleine, Nahid A. Khan, Anne Roivainen, Paivi Marjamäki, Heidi Liljenbäck, Liya Wang, Brendan J. Battersby, Uwe Richter, Vidya Velagapudi, Joni Nikkanen, Liliya Euro, Anu Suomalainen

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Cell Metabolism
Volume	30
Issue number	6
Pages (from-to)	1040-+
Number of pages	22
ISSN	1550-4131
DOIs	https://doi.org/10.1016/j.cmet.2019.013.019
Publication status	Published - 3 Dec 2019
MoE publication type	A1 Journal article-refereed

Fields of Science

MULTIPLE DELETIONS
METABOLIC-ACTIVITY
DNA DELETIONS
BETA-KLOTHO
PPAR-ALPHA
MUSCLE
FGF21
OPA1
ACTIVATION
DEFICIENCIES
3121 General medicine, internal medicine and other clinical medicine
1182 Biochemistry, cell and molecular biology

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Cite this

Forsström, S., Jackson, C. B., Carroll, C. J., Kuronen, M., Pirinen, E., Pradhan, S., Marmyleva, A., Auranen, M., Kleine, I-M., Khan, N. A., Roivainen, A., Marjamäki, P., Liljenbäck, H., Wang, L., Battersby, B. J., Richter, U., Velagapudi, V., Nikkanen, J., Euro, L., & Suomalainen, A. (2019). Fibroblast Growth Factor 21 Drives Dynamics of Local and Systemic Stress Responses in Mitochondrial Myopathy with mtDNA Deletions. Cell Metabolism, 30(6), 1040-+. https://doi.org/10.1016/j.cmet.2019.013.019

Forsström, Saara ; Jackson, Christopher B. ; Carroll, Christopher J. ; Kuronen, Mervi ; Pirinen, Eija ; Pradhan, Swagat ; Marmyleva, Anastasiia ; Auranen, Mari ; Kleine, Iida-Marja ; Khan, Nahid A. ; Roivainen, Anne ; Marjamäki, Paivi ; Liljenbäck, Heidi ; Wang, Liya ; Battersby, Brendan J. ; Richter, Uwe ; Velagapudi, Vidya ; Nikkanen, Joni ; Euro, Liliya ; Suomalainen, Anu. / Fibroblast Growth Factor 21 Drives Dynamics of Local and Systemic Stress Responses in Mitochondrial Myopathy with mtDNA Deletions. In: Cell Metabolism. 2019 ; Vol. 30, No. 6. pp. 1040-+.

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title = "Fibroblast Growth Factor 21 Drives Dynamics of Local and Systemic Stress Responses in Mitochondrial Myopathy with mtDNA Deletions",

keywords = "MULTIPLE DELETIONS, METABOLIC-ACTIVITY, DNA DELETIONS, BETA-KLOTHO, PPAR-ALPHA, MUSCLE, FGF21, OPA1, ACTIVATION, DEFICIENCIES, 3121 General medicine, internal medicine and other clinical medicine, 1182 Biochemistry, cell and molecular biology",

author = "Saara Forsstr{\"o}m and Jackson, {Christopher B.} and Carroll, {Christopher J.} and Mervi Kuronen and Eija Pirinen and Swagat Pradhan and Anastasiia Marmyleva and Mari Auranen and Iida-Marja Kleine and Khan, {Nahid A.} and Anne Roivainen and Paivi Marjam{\"a}ki and Heidi Liljenb{\"a}ck and Liya Wang and Battersby, {Brendan J.} and Uwe Richter and Vidya Velagapudi and Joni Nikkanen and Liliya Euro and Anu Suomalainen",

year = "2019",

month = dec,

day = "3",

doi = "10.1016/j.cmet.2019.013.019",

language = "English",

volume = "30",

pages = "1040--+",

journal = "Cell Metabolism",

issn = "1550-4131",

publisher = "Cell Press",

number = "6",

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Forsström, S , Jackson, CB, Carroll, CJ, Kuronen, M, Pirinen, E , Pradhan, S , Marmyleva, A , Auranen, M, Kleine, I-M, Khan, NA, Roivainen, A, Marjamäki, P, Liljenbäck, H, Wang, L, Battersby, BJ , Richter, U , Velagapudi, V, Nikkanen, J, Euro, L & Suomalainen, A 2019, 'Fibroblast Growth Factor 21 Drives Dynamics of Local and Systemic Stress Responses in Mitochondrial Myopathy with mtDNA Deletions', Cell Metabolism, vol. 30, no. 6, pp. 1040-+. https://doi.org/10.1016/j.cmet.2019.013.019

Fibroblast Growth Factor 21 Drives Dynamics of Local and Systemic Stress Responses in Mitochondrial Myopathy with mtDNA Deletions. / Forsström, Saara ; Jackson, Christopher B.; Carroll, Christopher J.; Kuronen, Mervi; Pirinen, Eija ; Pradhan, Swagat ; Marmyleva, Anastasiia ; Auranen, Mari; Kleine, Iida-Marja; Khan, Nahid A.; Roivainen, Anne; Marjamäki, Paivi; Liljenbäck, Heidi; Wang, Liya; Battersby, Brendan J.; Richter, Uwe ; Velagapudi, Vidya; Nikkanen, Joni; Euro, Liliya ; Suomalainen, Anu.

In: Cell Metabolism, Vol. 30, No. 6, 03.12.2019, p. 1040-+.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - Fibroblast Growth Factor 21 Drives Dynamics of Local and Systemic Stress Responses in Mitochondrial Myopathy with mtDNA Deletions

AU - Forsström, Saara

AU - Jackson, Christopher B.

AU - Carroll, Christopher J.

AU - Kuronen, Mervi

AU - Pirinen, Eija

AU - Pradhan, Swagat

AU - Marmyleva, Anastasiia

AU - Auranen, Mari

AU - Kleine, Iida-Marja

AU - Khan, Nahid A.

AU - Roivainen, Anne

AU - Marjamäki, Paivi

AU - Liljenbäck, Heidi

AU - Wang, Liya

AU - Battersby, Brendan J.

AU - Richter, Uwe

AU - Velagapudi, Vidya

AU - Nikkanen, Joni

AU - Euro, Liliya

AU - Suomalainen, Anu

PY - 2019/12/3

Y1 - 2019/12/3

KW - MULTIPLE DELETIONS

KW - METABOLIC-ACTIVITY

KW - DNA DELETIONS

KW - BETA-KLOTHO

KW - PPAR-ALPHA

KW - MUSCLE

KW - FGF21

KW - OPA1

KW - ACTIVATION

KW - DEFICIENCIES

KW - 3121 General medicine, internal medicine and other clinical medicine

KW - 1182 Biochemistry, cell and molecular biology

U2 - 10.1016/j.cmet.2019.013.019

DO - 10.1016/j.cmet.2019.013.019

M3 - Article

VL - 30

SP - 1040-+

JO - Cell Metabolism

JF - Cell Metabolism

SN - 1550-4131

IS - 6

ER -