FTO genotype is associated with phenotypic variability of body mass index

Jian Yang, Ruth J. F. Loos, Joseph E. Powell, Sarah E. Medland, Elizabeth K. Speliotes, Daniel I. Chasman, Lynda M. Rose, Gudmar Thorleifsson, Valgerdur Steinthorsdottir, Reedik Maegi, Lindsay Waite, Albert Vernon Smith, Laura M. Yerges-Armstrong, Keri L. Monda, David Hadley, Anubha Mahajan, Guo Li, Karen Kapur, Veronique Vitart, Jennifer E. HuffmanSophie R. Wang, Cameron Palmer, Toenu Esko, Krista Fischer, Jing Hua Zhao, Ayse Demirkan, Aaron Isaacs, Mary F. Feitosa, Jian'an Luan, Nancy L. Heard-Costa, Charles White, Anne U. Jackson, Michael Preuss, Andreas Ziegler, Joel Eriksson, Zoltan Kutalik, Francesca Frau, Ilja M. Nolte, Jana V. Van Vliet-Ostaptchouk, Jouke-Jan Hottenga, Kevin B. Jacobs, Niek Verweij, Anuj Goel, Carolina Medina-Gomez, Karol Estrada, Jennifer Lynn Bragg-Gresham, Serena Sanna, Carlo Sidore, Jonathan Tyrer, Alexander Teumer, Inga Prokopenko, Massimo Mangino, Cecilia M. Lindgren, Themistocles L. Assimes, Alan R. Shuldiner, Jennie Hui, John P. Beilby, Wendy L. McArdle, Per Hall, Talin Haritunians, Lina Zgaga, Ivana Kolcic, Ozren Polasek, Tatijana Zemunik, Ben A. Oostra, M. Juhani Junttila, Henrik Groenberg, Stefan Schreiber, Annette Peters, Andrew A. Hicks, Jonathan Stephens, Nicola S. Foad, Jaana Laitinen, Anneli Pouta, Marika Kaakinen, Gonneke Willemsen, Jacqueline M. Vink, Sarah H. Wild, Gerjan Navis, Folkert W. Asselbergs, Georg Homuth, Ulrich John, Carlos Iribarren, Tamara Harris, Lenore Launer, Vilmundur Gudnason, Jeffrey R. O'Connell, Eric Boerwinkle, Gemma Cadby, Lyle J. Palmer, Alan L. James, Arthur W. Musk, Erik Ingelsson, Bruce M. Psaty, Jacques S. Beckmann, Gerard Waeber, Peter Vollenweider, Caroline Hayward, Alan F. Wright, Igor Rudan, Leif C. Groop, Andres Metspalu, Kay Tee Khaw, Cornelia M. van Duijn, Ingrid B. Borecki, Michael A. Province, Nicholas J. Wareham, Jean-Claude Tardif, Heikki V. Huikuri, L. Adrienne Cupples, Larry D. Atwood, Caroline S. Fox, Michael Boehnke, Francis S. Collins, Karen L. Mohlke, Jeanette Erdmann, Heribert Schunkert, Christian Hengstenberg, Klaus Stark, Mattias Lorentzon, Claes Ohlsson, Daniele Cusi, Jan A. Staessen, Melanie M. Van der Klauw, Peter P. Pramstaller, Sekar Kathiresan, Jennifer D. Jolley, Samuli Ripatti, Marjo-Riitta Jarvelin, Eco J. C. de Geus, Dorret I. Boomsma, Brenda Penninx, James F. Wilson, Harry Campbell, Stephen J. Chanock, Pim van der Harst, Anders Hamsten, Hugh Watkins, Albert Hofman, Jacqueline C. Witteman, M. Carola Zillikens, Andre G. Uitterlinden, Fernando Rivadeneira, M. Carola Zillikens, Lambertus A. Kiemeney, Sita H. Vermeulen, Goncalo R. Abecasis, David Schlessinger, Sabine Schipf, Michael Stumvoll, Anke Toenjes, Tim D. Spector, Kari E. North, Guillaume Lettre, Mark I. McCarthy, Sonja I. Berndt, Andrew C. Heath, Pamela A. F. Madden, Dale R. Nyholt, Grant W. Montgomery, Nicholas G. Martin, Barbara McKnight, David P. Strachan, William G. Hill, Harold Snieder, Paul M. Ridker, Unnur Thorsteinsdottir, Kari Stefansson, Timothy M. Frayling, Joel N. Hirschhorn, Michael E. Goddard, Peter M. Visscher

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalNature
Volume490
Issue number7419
Pages (from-to)267-U178
Number of pages7
ISSN0028-0836
DOIs
Publication statusPublished - 11 Oct 2012
MoE publication typeA1 Journal article-refereed

Fields of Science

  • GENOME-WIDE ASSOCIATION
  • ENVIRONMENTAL SENSITIVITY
  • PHYSICAL-ACTIVITY
  • GENETIC-VARIATION
  • ADULT OBESITY
  • LOCI
  • VARIANTS
  • CHILDHOOD
  • SELECTION
  • TRAITS
  • 3111 Biomedicine

Cite this

Yang, J., Loos, R. J. F., Powell, J. E., Medland, S. E., Speliotes, E. K., Chasman, D. I., ... Visscher, P. M. (2012). FTO genotype is associated with phenotypic variability of body mass index. Nature, 490(7419), 267-U178. https://doi.org/10.1038/nature11401
Yang, Jian ; Loos, Ruth J. F. ; Powell, Joseph E. ; Medland, Sarah E. ; Speliotes, Elizabeth K. ; Chasman, Daniel I. ; Rose, Lynda M. ; Thorleifsson, Gudmar ; Steinthorsdottir, Valgerdur ; Maegi, Reedik ; Waite, Lindsay ; Smith, Albert Vernon ; Yerges-Armstrong, Laura M. ; Monda, Keri L. ; Hadley, David ; Mahajan, Anubha ; Li, Guo ; Kapur, Karen ; Vitart, Veronique ; Huffman, Jennifer E. ; Wang, Sophie R. ; Palmer, Cameron ; Esko, Toenu ; Fischer, Krista ; Zhao, Jing Hua ; Demirkan, Ayse ; Isaacs, Aaron ; Feitosa, Mary F. ; Luan, Jian'an ; Heard-Costa, Nancy L. ; White, Charles ; Jackson, Anne U. ; Preuss, Michael ; Ziegler, Andreas ; Eriksson, Joel ; Kutalik, Zoltan ; Frau, Francesca ; Nolte, Ilja M. ; Van Vliet-Ostaptchouk, Jana V. ; Hottenga, Jouke-Jan ; Jacobs, Kevin B. ; Verweij, Niek ; Goel, Anuj ; Medina-Gomez, Carolina ; Estrada, Karol ; Bragg-Gresham, Jennifer Lynn ; Sanna, Serena ; Sidore, Carlo ; Tyrer, Jonathan ; Teumer, Alexander ; Prokopenko, Inga ; Mangino, Massimo ; Lindgren, Cecilia M. ; Assimes, Themistocles L. ; Shuldiner, Alan R. ; Hui, Jennie ; Beilby, John P. ; McArdle, Wendy L. ; Hall, Per ; Haritunians, Talin ; Zgaga, Lina ; Kolcic, Ivana ; Polasek, Ozren ; Zemunik, Tatijana ; Oostra, Ben A. ; Junttila, M. Juhani ; Groenberg, Henrik ; Schreiber, Stefan ; Peters, Annette ; Hicks, Andrew A. ; Stephens, Jonathan ; Foad, Nicola S. ; Laitinen, Jaana ; Pouta, Anneli ; Kaakinen, Marika ; Willemsen, Gonneke ; Vink, Jacqueline M. ; Wild, Sarah H. ; Navis, Gerjan ; Asselbergs, Folkert W. ; Homuth, Georg ; John, Ulrich ; Iribarren, Carlos ; Harris, Tamara ; Launer, Lenore ; Gudnason, Vilmundur ; O'Connell, Jeffrey R. ; Boerwinkle, Eric ; Cadby, Gemma ; Palmer, Lyle J. ; James, Alan L. ; Musk, Arthur W. ; Ingelsson, Erik ; Psaty, Bruce M. ; Beckmann, Jacques S. ; Waeber, Gerard ; Vollenweider, Peter ; Hayward, Caroline ; Wright, Alan F. ; Rudan, Igor ; Groop, Leif C. ; Metspalu, Andres ; Khaw, Kay Tee ; van Duijn, Cornelia M. ; Borecki, Ingrid B. ; Province, Michael A. ; Wareham, Nicholas J. ; Tardif, Jean-Claude ; Huikuri, Heikki V. ; Cupples, L. Adrienne ; Atwood, Larry D. ; Fox, Caroline S. ; Boehnke, Michael ; Collins, Francis S. ; Mohlke, Karen L. ; Erdmann, Jeanette ; Schunkert, Heribert ; Hengstenberg, Christian ; Stark, Klaus ; Lorentzon, Mattias ; Ohlsson, Claes ; Cusi, Daniele ; Staessen, Jan A. ; Van der Klauw, Melanie M. ; Pramstaller, Peter P. ; Kathiresan, Sekar ; Jolley, Jennifer D. ; Ripatti, Samuli ; Jarvelin, Marjo-Riitta ; de Geus, Eco J. C. ; Boomsma, Dorret I. ; Penninx, Brenda ; Wilson, James F. ; Campbell, Harry ; Chanock, Stephen J. ; van der Harst, Pim ; Hamsten, Anders ; Watkins, Hugh ; Hofman, Albert ; Witteman, Jacqueline C. ; Zillikens, M. Carola ; Uitterlinden, Andre G. ; Rivadeneira, Fernando ; Zillikens, M. Carola ; Kiemeney, Lambertus A. ; Vermeulen, Sita H. ; Abecasis, Goncalo R. ; Schlessinger, David ; Schipf, Sabine ; Stumvoll, Michael ; Toenjes, Anke ; Spector, Tim D. ; North, Kari E. ; Lettre, Guillaume ; McCarthy, Mark I. ; Berndt, Sonja I. ; Heath, Andrew C. ; Madden, Pamela A. F. ; Nyholt, Dale R. ; Montgomery, Grant W. ; Martin, Nicholas G. ; McKnight, Barbara ; Strachan, David P. ; Hill, William G. ; Snieder, Harold ; Ridker, Paul M. ; Thorsteinsdottir, Unnur ; Stefansson, Kari ; Frayling, Timothy M. ; Hirschhorn, Joel N. ; Goddard, Michael E. ; Visscher, Peter M. / FTO genotype is associated with phenotypic variability of body mass index. In: Nature. 2012 ; Vol. 490, No. 7419. pp. 267-U178.
@article{259c96fafbc141b6a09df5bbdbe0317c,
title = "FTO genotype is associated with phenotypic variability of body mass index",
keywords = "GENOME-WIDE ASSOCIATION, ENVIRONMENTAL SENSITIVITY, PHYSICAL-ACTIVITY, GENETIC-VARIATION, ADULT OBESITY, LOCI, VARIANTS, CHILDHOOD, SELECTION, TRAITS, 3111 Biomedicine",
author = "Jian Yang and Loos, {Ruth J. F.} and Powell, {Joseph E.} and Medland, {Sarah E.} and Speliotes, {Elizabeth K.} and Chasman, {Daniel I.} and Rose, {Lynda M.} and Gudmar Thorleifsson and Valgerdur Steinthorsdottir and Reedik Maegi and Lindsay Waite and Smith, {Albert Vernon} and Yerges-Armstrong, {Laura M.} and Monda, {Keri L.} and David Hadley and Anubha Mahajan and Guo Li and Karen Kapur and Veronique Vitart and Huffman, {Jennifer E.} and Wang, {Sophie R.} and Cameron Palmer and Toenu Esko and Krista Fischer and Zhao, {Jing Hua} and Ayse Demirkan and Aaron Isaacs and Feitosa, {Mary F.} and Jian'an Luan and Heard-Costa, {Nancy L.} and Charles White and Jackson, {Anne U.} and Michael Preuss and Andreas Ziegler and Joel Eriksson and Zoltan Kutalik and Francesca Frau and Nolte, {Ilja M.} and {Van Vliet-Ostaptchouk}, {Jana V.} and Jouke-Jan Hottenga and Jacobs, {Kevin B.} and Niek Verweij and Anuj Goel and Carolina Medina-Gomez and Karol Estrada and Bragg-Gresham, {Jennifer Lynn} and Serena Sanna and Carlo Sidore and Jonathan Tyrer and Alexander Teumer and Inga Prokopenko and Massimo Mangino and Lindgren, {Cecilia M.} and Assimes, {Themistocles L.} and Shuldiner, {Alan R.} and Jennie Hui and Beilby, {John P.} and McArdle, {Wendy L.} and Per Hall and Talin Haritunians and Lina Zgaga and Ivana Kolcic and Ozren Polasek and Tatijana Zemunik and Oostra, {Ben A.} and Junttila, {M. Juhani} and Henrik Groenberg and Stefan Schreiber and Annette Peters and Hicks, {Andrew A.} and Jonathan Stephens and Foad, {Nicola S.} and Jaana Laitinen and Anneli Pouta and Marika Kaakinen and Gonneke Willemsen and Vink, {Jacqueline M.} and Wild, {Sarah H.} and Gerjan Navis and Asselbergs, {Folkert W.} and Georg Homuth and Ulrich John and Carlos Iribarren and Tamara Harris and Lenore Launer and Vilmundur Gudnason and O'Connell, {Jeffrey R.} and Eric Boerwinkle and Gemma Cadby and Palmer, {Lyle J.} and James, {Alan L.} and Musk, {Arthur W.} and Erik Ingelsson and Psaty, {Bruce M.} and Beckmann, {Jacques S.} and Gerard Waeber and Peter Vollenweider and Caroline Hayward and Wright, {Alan F.} and Igor Rudan and Groop, {Leif C.} and Andres Metspalu and Khaw, {Kay Tee} and {van Duijn}, {Cornelia M.} and Borecki, {Ingrid B.} and Province, {Michael A.} and Wareham, {Nicholas J.} and Jean-Claude Tardif and Huikuri, {Heikki V.} and Cupples, {L. Adrienne} and Atwood, {Larry D.} and Fox, {Caroline S.} and Michael Boehnke and Collins, {Francis S.} and Mohlke, {Karen L.} and Jeanette Erdmann and Heribert Schunkert and Christian Hengstenberg and Klaus Stark and Mattias Lorentzon and Claes Ohlsson and Daniele Cusi and Staessen, {Jan A.} and {Van der Klauw}, {Melanie M.} and Pramstaller, {Peter P.} and Sekar Kathiresan and Jolley, {Jennifer D.} and Samuli Ripatti and Marjo-Riitta Jarvelin and {de Geus}, {Eco J. C.} and Boomsma, {Dorret I.} and Brenda Penninx and Wilson, {James F.} and Harry Campbell and Chanock, {Stephen J.} and {van der Harst}, Pim and Anders Hamsten and Hugh Watkins and Albert Hofman and Witteman, {Jacqueline C.} and Zillikens, {M. Carola} and Uitterlinden, {Andre G.} and Fernando Rivadeneira and Zillikens, {M. Carola} and Kiemeney, {Lambertus A.} and Vermeulen, {Sita H.} and Abecasis, {Goncalo R.} and David Schlessinger and Sabine Schipf and Michael Stumvoll and Anke Toenjes and Spector, {Tim D.} and North, {Kari E.} and Guillaume Lettre and McCarthy, {Mark I.} and Berndt, {Sonja I.} and Heath, {Andrew C.} and Madden, {Pamela A. F.} and Nyholt, {Dale R.} and Montgomery, {Grant W.} and Martin, {Nicholas G.} and Barbara McKnight and Strachan, {David P.} and Hill, {William G.} and Harold Snieder and Ridker, {Paul M.} and Unnur Thorsteinsdottir and Kari Stefansson and Frayling, {Timothy M.} and Hirschhorn, {Joel N.} and Goddard, {Michael E.} and Visscher, {Peter M.}",
year = "2012",
month = "10",
day = "11",
doi = "10.1038/nature11401",
language = "English",
volume = "490",
pages = "267--U178",
journal = "Nature",
issn = "0028-0836",
publisher = "Nature Publishing Group",
number = "7419",

}

Yang, J, Loos, RJF, Powell, JE, Medland, SE, Speliotes, EK, Chasman, DI, Rose, LM, Thorleifsson, G, Steinthorsdottir, V, Maegi, R, Waite, L, Smith, AV, Yerges-Armstrong, LM, Monda, KL, Hadley, D, Mahajan, A, Li, G, Kapur, K, Vitart, V, Huffman, JE, Wang, SR, Palmer, C, Esko, T, Fischer, K, Zhao, JH, Demirkan, A, Isaacs, A, Feitosa, MF, Luan, J, Heard-Costa, NL, White, C, Jackson, AU, Preuss, M, Ziegler, A, Eriksson, J, Kutalik, Z, Frau, F, Nolte, IM, Van Vliet-Ostaptchouk, JV, Hottenga, J-J, Jacobs, KB, Verweij, N, Goel, A, Medina-Gomez, C, Estrada, K, Bragg-Gresham, JL, Sanna, S, Sidore, C, Tyrer, J, Teumer, A, Prokopenko, I, Mangino, M, Lindgren, CM, Assimes, TL, Shuldiner, AR, Hui, J, Beilby, JP, McArdle, WL, Hall, P, Haritunians, T, Zgaga, L, Kolcic, I, Polasek, O, Zemunik, T, Oostra, BA, Junttila, MJ, Groenberg, H, Schreiber, S, Peters, A, Hicks, AA, Stephens, J, Foad, NS, Laitinen, J, Pouta, A, Kaakinen, M, Willemsen, G, Vink, JM, Wild, SH, Navis, G, Asselbergs, FW, Homuth, G, John, U, Iribarren, C, Harris, T, Launer, L, Gudnason, V, O'Connell, JR, Boerwinkle, E, Cadby, G, Palmer, LJ, James, AL, Musk, AW, Ingelsson, E, Psaty, BM, Beckmann, JS, Waeber, G, Vollenweider, P, Hayward, C, Wright, AF, Rudan, I, Groop, LC, Metspalu, A, Khaw, KT, van Duijn, CM, Borecki, IB, Province, MA, Wareham, NJ, Tardif, J-C, Huikuri, HV, Cupples, LA, Atwood, LD, Fox, CS, Boehnke, M, Collins, FS, Mohlke, KL, Erdmann, J, Schunkert, H, Hengstenberg, C, Stark, K, Lorentzon, M, Ohlsson, C, Cusi, D, Staessen, JA, Van der Klauw, MM, Pramstaller, PP, Kathiresan, S, Jolley, JD, Ripatti, S, Jarvelin, M-R, de Geus, EJC, Boomsma, DI, Penninx, B, Wilson, JF, Campbell, H, Chanock, SJ, van der Harst, P, Hamsten, A, Watkins, H, Hofman, A, Witteman, JC, Zillikens, MC, Uitterlinden, AG, Rivadeneira, F, Zillikens, MC, Kiemeney, LA, Vermeulen, SH, Abecasis, GR, Schlessinger, D, Schipf, S, Stumvoll, M, Toenjes, A, Spector, TD, North, KE, Lettre, G, McCarthy, MI, Berndt, SI, Heath, AC, Madden, PAF, Nyholt, DR, Montgomery, GW, Martin, NG, McKnight, B, Strachan, DP, Hill, WG, Snieder, H, Ridker, PM, Thorsteinsdottir, U, Stefansson, K, Frayling, TM, Hirschhorn, JN, Goddard, ME & Visscher, PM 2012, 'FTO genotype is associated with phenotypic variability of body mass index', Nature, vol. 490, no. 7419, pp. 267-U178. https://doi.org/10.1038/nature11401

FTO genotype is associated with phenotypic variability of body mass index. / Yang, Jian; Loos, Ruth J. F.; Powell, Joseph E.; Medland, Sarah E.; Speliotes, Elizabeth K.; Chasman, Daniel I.; Rose, Lynda M.; Thorleifsson, Gudmar; Steinthorsdottir, Valgerdur; Maegi, Reedik; Waite, Lindsay; Smith, Albert Vernon; Yerges-Armstrong, Laura M.; Monda, Keri L.; Hadley, David; Mahajan, Anubha; Li, Guo; Kapur, Karen; Vitart, Veronique; Huffman, Jennifer E.; Wang, Sophie R.; Palmer, Cameron; Esko, Toenu; Fischer, Krista; Zhao, Jing Hua; Demirkan, Ayse; Isaacs, Aaron; Feitosa, Mary F.; Luan, Jian'an; Heard-Costa, Nancy L.; White, Charles; Jackson, Anne U.; Preuss, Michael; Ziegler, Andreas; Eriksson, Joel; Kutalik, Zoltan; Frau, Francesca; Nolte, Ilja M.; Van Vliet-Ostaptchouk, Jana V.; Hottenga, Jouke-Jan; Jacobs, Kevin B.; Verweij, Niek; Goel, Anuj; Medina-Gomez, Carolina; Estrada, Karol; Bragg-Gresham, Jennifer Lynn; Sanna, Serena; Sidore, Carlo; Tyrer, Jonathan; Teumer, Alexander; Prokopenko, Inga; Mangino, Massimo; Lindgren, Cecilia M.; Assimes, Themistocles L.; Shuldiner, Alan R.; Hui, Jennie; Beilby, John P.; McArdle, Wendy L.; Hall, Per; Haritunians, Talin; Zgaga, Lina; Kolcic, Ivana; Polasek, Ozren; Zemunik, Tatijana; Oostra, Ben A.; Junttila, M. Juhani; Groenberg, Henrik; Schreiber, Stefan; Peters, Annette; Hicks, Andrew A.; Stephens, Jonathan; Foad, Nicola S.; Laitinen, Jaana; Pouta, Anneli; Kaakinen, Marika; Willemsen, Gonneke; Vink, Jacqueline M.; Wild, Sarah H.; Navis, Gerjan; Asselbergs, Folkert W.; Homuth, Georg; John, Ulrich; Iribarren, Carlos; Harris, Tamara; Launer, Lenore; Gudnason, Vilmundur; O'Connell, Jeffrey R.; Boerwinkle, Eric; Cadby, Gemma; Palmer, Lyle J.; James, Alan L.; Musk, Arthur W.; Ingelsson, Erik; Psaty, Bruce M.; Beckmann, Jacques S.; Waeber, Gerard; Vollenweider, Peter; Hayward, Caroline; Wright, Alan F.; Rudan, Igor; Groop, Leif C.; Metspalu, Andres; Khaw, Kay Tee; van Duijn, Cornelia M.; Borecki, Ingrid B.; Province, Michael A.; Wareham, Nicholas J.; Tardif, Jean-Claude; Huikuri, Heikki V.; Cupples, L. Adrienne; Atwood, Larry D.; Fox, Caroline S.; Boehnke, Michael; Collins, Francis S.; Mohlke, Karen L.; Erdmann, Jeanette; Schunkert, Heribert; Hengstenberg, Christian; Stark, Klaus; Lorentzon, Mattias; Ohlsson, Claes; Cusi, Daniele; Staessen, Jan A.; Van der Klauw, Melanie M.; Pramstaller, Peter P.; Kathiresan, Sekar; Jolley, Jennifer D.; Ripatti, Samuli; Jarvelin, Marjo-Riitta; de Geus, Eco J. C.; Boomsma, Dorret I.; Penninx, Brenda; Wilson, James F.; Campbell, Harry; Chanock, Stephen J.; van der Harst, Pim; Hamsten, Anders; Watkins, Hugh; Hofman, Albert; Witteman, Jacqueline C.; Zillikens, M. Carola; Uitterlinden, Andre G.; Rivadeneira, Fernando; Zillikens, M. Carola; Kiemeney, Lambertus A.; Vermeulen, Sita H.; Abecasis, Goncalo R.; Schlessinger, David; Schipf, Sabine; Stumvoll, Michael; Toenjes, Anke; Spector, Tim D.; North, Kari E.; Lettre, Guillaume; McCarthy, Mark I.; Berndt, Sonja I.; Heath, Andrew C.; Madden, Pamela A. F.; Nyholt, Dale R.; Montgomery, Grant W.; Martin, Nicholas G.; McKnight, Barbara; Strachan, David P.; Hill, William G.; Snieder, Harold; Ridker, Paul M.; Thorsteinsdottir, Unnur; Stefansson, Kari; Frayling, Timothy M.; Hirschhorn, Joel N.; Goddard, Michael E.; Visscher, Peter M.

In: Nature, Vol. 490, No. 7419, 11.10.2012, p. 267-U178.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - FTO genotype is associated with phenotypic variability of body mass index

AU - Yang, Jian

AU - Loos, Ruth J. F.

AU - Powell, Joseph E.

AU - Medland, Sarah E.

AU - Speliotes, Elizabeth K.

AU - Chasman, Daniel I.

AU - Rose, Lynda M.

AU - Thorleifsson, Gudmar

AU - Steinthorsdottir, Valgerdur

AU - Maegi, Reedik

AU - Waite, Lindsay

AU - Smith, Albert Vernon

AU - Yerges-Armstrong, Laura M.

AU - Monda, Keri L.

AU - Hadley, David

AU - Mahajan, Anubha

AU - Li, Guo

AU - Kapur, Karen

AU - Vitart, Veronique

AU - Huffman, Jennifer E.

AU - Wang, Sophie R.

AU - Palmer, Cameron

AU - Esko, Toenu

AU - Fischer, Krista

AU - Zhao, Jing Hua

AU - Demirkan, Ayse

AU - Isaacs, Aaron

AU - Feitosa, Mary F.

AU - Luan, Jian'an

AU - Heard-Costa, Nancy L.

AU - White, Charles

AU - Jackson, Anne U.

AU - Preuss, Michael

AU - Ziegler, Andreas

AU - Eriksson, Joel

AU - Kutalik, Zoltan

AU - Frau, Francesca

AU - Nolte, Ilja M.

AU - Van Vliet-Ostaptchouk, Jana V.

AU - Hottenga, Jouke-Jan

AU - Jacobs, Kevin B.

AU - Verweij, Niek

AU - Goel, Anuj

AU - Medina-Gomez, Carolina

AU - Estrada, Karol

AU - Bragg-Gresham, Jennifer Lynn

AU - Sanna, Serena

AU - Sidore, Carlo

AU - Tyrer, Jonathan

AU - Teumer, Alexander

AU - Prokopenko, Inga

AU - Mangino, Massimo

AU - Lindgren, Cecilia M.

AU - Assimes, Themistocles L.

AU - Shuldiner, Alan R.

AU - Hui, Jennie

AU - Beilby, John P.

AU - McArdle, Wendy L.

AU - Hall, Per

AU - Haritunians, Talin

AU - Zgaga, Lina

AU - Kolcic, Ivana

AU - Polasek, Ozren

AU - Zemunik, Tatijana

AU - Oostra, Ben A.

AU - Junttila, M. Juhani

AU - Groenberg, Henrik

AU - Schreiber, Stefan

AU - Peters, Annette

AU - Hicks, Andrew A.

AU - Stephens, Jonathan

AU - Foad, Nicola S.

AU - Laitinen, Jaana

AU - Pouta, Anneli

AU - Kaakinen, Marika

AU - Willemsen, Gonneke

AU - Vink, Jacqueline M.

AU - Wild, Sarah H.

AU - Navis, Gerjan

AU - Asselbergs, Folkert W.

AU - Homuth, Georg

AU - John, Ulrich

AU - Iribarren, Carlos

AU - Harris, Tamara

AU - Launer, Lenore

AU - Gudnason, Vilmundur

AU - O'Connell, Jeffrey R.

AU - Boerwinkle, Eric

AU - Cadby, Gemma

AU - Palmer, Lyle J.

AU - James, Alan L.

AU - Musk, Arthur W.

AU - Ingelsson, Erik

AU - Psaty, Bruce M.

AU - Beckmann, Jacques S.

AU - Waeber, Gerard

AU - Vollenweider, Peter

AU - Hayward, Caroline

AU - Wright, Alan F.

AU - Rudan, Igor

AU - Groop, Leif C.

AU - Metspalu, Andres

AU - Khaw, Kay Tee

AU - van Duijn, Cornelia M.

AU - Borecki, Ingrid B.

AU - Province, Michael A.

AU - Wareham, Nicholas J.

AU - Tardif, Jean-Claude

AU - Huikuri, Heikki V.

AU - Cupples, L. Adrienne

AU - Atwood, Larry D.

AU - Fox, Caroline S.

AU - Boehnke, Michael

AU - Collins, Francis S.

AU - Mohlke, Karen L.

AU - Erdmann, Jeanette

AU - Schunkert, Heribert

AU - Hengstenberg, Christian

AU - Stark, Klaus

AU - Lorentzon, Mattias

AU - Ohlsson, Claes

AU - Cusi, Daniele

AU - Staessen, Jan A.

AU - Van der Klauw, Melanie M.

AU - Pramstaller, Peter P.

AU - Kathiresan, Sekar

AU - Jolley, Jennifer D.

AU - Ripatti, Samuli

AU - Jarvelin, Marjo-Riitta

AU - de Geus, Eco J. C.

AU - Boomsma, Dorret I.

AU - Penninx, Brenda

AU - Wilson, James F.

AU - Campbell, Harry

AU - Chanock, Stephen J.

AU - van der Harst, Pim

AU - Hamsten, Anders

AU - Watkins, Hugh

AU - Hofman, Albert

AU - Witteman, Jacqueline C.

AU - Zillikens, M. Carola

AU - Uitterlinden, Andre G.

AU - Rivadeneira, Fernando

AU - Zillikens, M. Carola

AU - Kiemeney, Lambertus A.

AU - Vermeulen, Sita H.

AU - Abecasis, Goncalo R.

AU - Schlessinger, David

AU - Schipf, Sabine

AU - Stumvoll, Michael

AU - Toenjes, Anke

AU - Spector, Tim D.

AU - North, Kari E.

AU - Lettre, Guillaume

AU - McCarthy, Mark I.

AU - Berndt, Sonja I.

AU - Heath, Andrew C.

AU - Madden, Pamela A. F.

AU - Nyholt, Dale R.

AU - Montgomery, Grant W.

AU - Martin, Nicholas G.

AU - McKnight, Barbara

AU - Strachan, David P.

AU - Hill, William G.

AU - Snieder, Harold

AU - Ridker, Paul M.

AU - Thorsteinsdottir, Unnur

AU - Stefansson, Kari

AU - Frayling, Timothy M.

AU - Hirschhorn, Joel N.

AU - Goddard, Michael E.

AU - Visscher, Peter M.

PY - 2012/10/11

Y1 - 2012/10/11

KW - GENOME-WIDE ASSOCIATION

KW - ENVIRONMENTAL SENSITIVITY

KW - PHYSICAL-ACTIVITY

KW - GENETIC-VARIATION

KW - ADULT OBESITY

KW - LOCI

KW - VARIANTS

KW - CHILDHOOD

KW - SELECTION

KW - TRAITS

KW - 3111 Biomedicine

U2 - 10.1038/nature11401

DO - 10.1038/nature11401

M3 - Article

VL - 490

SP - 267-U178

JO - Nature

JF - Nature

SN - 0028-0836

IS - 7419

ER -

Yang J, Loos RJF, Powell JE, Medland SE, Speliotes EK, Chasman DI et al. FTO genotype is associated with phenotypic variability of body mass index. Nature. 2012 Oct 11;490(7419):267-U178. https://doi.org/10.1038/nature11401