Functional characterization of human pluripotent stem cell-derived cortical networks differentiated on laminin-521 substrate: comparison to rat cortical cultures

Tanja Hyvärinen; Anu Hyysalo; Fikret Emre Kapucu; Laura Aarnos; Andrey Vinogradov; Stephen J. Eglen; Laura Ylä-Outinen; Susanna Narkilahti

doi:10.1038/s41598-019-53647-8

Functional characterization of human pluripotent stem cell-derived cortical networks differentiated on laminin-521 substrate: comparison to rat cortical cultures

Tanja Hyvärinen, Anu Hyysalo, Fikret Emre Kapucu, Laura Aarnos, Andrey Vinogradov, Stephen J. Eglen, Laura Ylä-Outinen, Susanna Narkilahti

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	17125
Journal	Scientific Reports
Volume	9
Number of pages	15
ISSN	2045-2322
DOIs	https://doi.org/10.1038/s41598-019-53647-8
Publication status	Published - 20 Nov 2019
MoE publication type	A1 Journal article-refereed

Fields of Science

LONG-TERM POTENTIATION
ELECTRICAL-ACTIVITY
XENO-FREE
ACTIVITY PATTERNS
CEREBRAL-CORTEX
SPIKE DETECTION
NEURONS
DERIVATION
INDUCTION
LINES
3112 Neurosciences
1182 Biochemistry, cell and molecular biology
3111 Biomedicine

Access to Document

10.1038/s41598-019-53647-8

s41598-019-53647-8Final published version, 5.72 MBLicence: CC BY

Cite this

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title = "Functional characterization of human pluripotent stem cell-derived cortical networks differentiated on laminin-521 substrate: comparison to rat cortical cultures",

keywords = "LONG-TERM POTENTIATION, ELECTRICAL-ACTIVITY, XENO-FREE, ACTIVITY PATTERNS, CEREBRAL-CORTEX, SPIKE DETECTION, NEURONS, DERIVATION, INDUCTION, LINES, 3112 Neurosciences, 1182 Biochemistry, cell and molecular biology, 3111 Biomedicine",

author = "Tanja Hyv{\"a}rinen and Anu Hyysalo and Kapucu, {Fikret Emre} and Laura Aarnos and Andrey Vinogradov and Eglen, {Stephen J.} and Laura Yl{\"a}-Outinen and Susanna Narkilahti",

year = "2019",

month = nov,

day = "20",

doi = "10.1038/s41598-019-53647-8",

language = "English",

volume = "9",

journal = "Scientific Reports",

issn = "2045-2322",

publisher = "Nature Publishing Group",

}

Functional characterization of human pluripotent stem cell-derived cortical networks differentiated on laminin-521 substrate : comparison to rat cortical cultures. / Hyvärinen, Tanja; Hyysalo, Anu; Kapucu, Fikret Emre; Aarnos, Laura; Vinogradov, Andrey; Eglen, Stephen J.; Ylä-Outinen, Laura; Narkilahti, Susanna.

In: Scientific Reports, Vol. 9, 17125, 20.11.2019.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - Functional characterization of human pluripotent stem cell-derived cortical networks differentiated on laminin-521 substrate

T2 - comparison to rat cortical cultures

AU - Hyvärinen, Tanja

AU - Hyysalo, Anu

AU - Kapucu, Fikret Emre

AU - Aarnos, Laura

AU - Vinogradov, Andrey

AU - Eglen, Stephen J.

AU - Ylä-Outinen, Laura

AU - Narkilahti, Susanna

PY - 2019/11/20

Y1 - 2019/11/20

KW - LONG-TERM POTENTIATION

KW - ELECTRICAL-ACTIVITY

KW - XENO-FREE

KW - ACTIVITY PATTERNS

KW - CEREBRAL-CORTEX

KW - SPIKE DETECTION

KW - NEURONS

KW - DERIVATION

KW - INDUCTION

KW - LINES

KW - 3112 Neurosciences

KW - 1182 Biochemistry, cell and molecular biology

KW - 3111 Biomedicine

U2 - 10.1038/s41598-019-53647-8

DO - 10.1038/s41598-019-53647-8

M3 - Article

VL - 9

JO - Scientific Reports

JF - Scientific Reports

SN - 2045-2322

M1 - 17125

ER -