GABA(B) receptor positive allosteric modulators with different efficacies affect neuroadaptation to and self-administration of alcohol and cocaine

Elena de Miguel, Olga Vekovischeva, Katja Kuokkanen, Marja Vesajoki, Nelli Paasikoski, Janne Kaskinoro, Mikko Myllymäki, Mira Lainiola, Sanna K. Janhunen, Petri Hyytiä, Anni-Maija Linden, Esa R. Korpi

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalAddiction Biology
Volume24
Issue number6
Pages (from-to)1191-1203
Number of pages13
ISSN1355-6215
DOIs
Publication statusPublished - Nov 2019
MoE publication typeA1 Journal article-refereed

Fields of Science

  • alcohol drinking
  • cocaine self-administration
  • GABA(B) receptor positive allosteric modulators
  • glutamate neuroplasticity
  • VENTRAL TEGMENTAL AREA
  • CONDITIONED PLACE PREFERENCE
  • LONG-TERM POTENTIATION
  • HIGH-DOSE BACLOFEN
  • DOPAMINE NEURONS
  • NUCLEUS-ACCUMBENS
  • DOUBLE-BLIND
  • NMDA RECEPTORS
  • RAC-BHFF
  • DEPENDENCE
  • 3111 Biomedicine
  • 1182 Biochemistry, cell and molecular biology

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