Gain-of-Function Mutation of the SCN5A Gene Causes Exercise-Induced Polymorphic Ventricular Arrhythmias

Heikki Swan, Mohamed Yassine Amarouch, Jaakko Leinonen, Annukka Marjamaa, Jan P. Kucera, Päivi J. Laitinen-Forsblom, Annukka M. Lahtinen, Aarno Palotie, Kimmo Kontula, Lauri Toivonen, Hugues Abriel, Elisabeth Widen

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalCirculation. Cardiovascular genetics
Volume7
Issue number6
Pages (from-to)771-U111
Number of pages17
ISSN1942-325X
DOIs
Publication statusPublished - Dec 2014
MoE publication typeA1 Journal article-refereed

Fields of Science

  • arrhythmia (heart rhythm disorders)
  • catecholaminergic polymorphic ventricular tachycardia
  • exercise test
  • genetic testing
  • mutation
  • SCN5A
  • LONG QT SYNDROME
  • CARDIAC SODIUM-CHANNEL
  • BRUGADA-SYNDROME
  • CA2+ SPARK
  • IN-VITRO
  • TACHYCARDIA
  • MODEL
  • DISEASE
  • FAMILY
  • ERYTHROMELALGIA
  • 3121 Internal medicine

Cite this

@article{00e808fb2e2c4c569da47f0b0d4bfbc3,
title = "Gain-of-Function Mutation of the SCN5A Gene Causes Exercise-Induced Polymorphic Ventricular Arrhythmias",
keywords = "arrhythmia (heart rhythm disorders), catecholaminergic polymorphic ventricular tachycardia, exercise test, genetic testing, mutation, SCN5A, LONG QT SYNDROME, CARDIAC SODIUM-CHANNEL, BRUGADA-SYNDROME, CA2+ SPARK, IN-VITRO, TACHYCARDIA, MODEL, DISEASE, FAMILY, ERYTHROMELALGIA, 3121 Internal medicine",
author = "Heikki Swan and Amarouch, {Mohamed Yassine} and Jaakko Leinonen and Annukka Marjamaa and Kucera, {Jan P.} and Laitinen-Forsblom, {P{\"a}ivi J.} and Lahtinen, {Annukka M.} and Aarno Palotie and Kimmo Kontula and Lauri Toivonen and Hugues Abriel and Elisabeth Widen",
year = "2014",
month = "12",
doi = "10.1161/CIRCGENETICS.114.000703",
language = "English",
volume = "7",
pages = "771--U111",
journal = "Circulation. Cardiovascular genetics",
issn = "1942-325X",
publisher = "LIPPINCOTT WILLIAMS & WILKINS",
number = "6",

}

Gain-of-Function Mutation of the SCN5A Gene Causes Exercise-Induced Polymorphic Ventricular Arrhythmias. / Swan, Heikki; Amarouch, Mohamed Yassine; Leinonen, Jaakko; Marjamaa, Annukka; Kucera, Jan P.; Laitinen-Forsblom, Päivi J.; Lahtinen, Annukka M.; Palotie, Aarno; Kontula, Kimmo; Toivonen, Lauri; Abriel, Hugues; Widen, Elisabeth.

In: Circulation. Cardiovascular genetics, Vol. 7, No. 6, 12.2014, p. 771-U111.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Gain-of-Function Mutation of the SCN5A Gene Causes Exercise-Induced Polymorphic Ventricular Arrhythmias

AU - Swan, Heikki

AU - Amarouch, Mohamed Yassine

AU - Leinonen, Jaakko

AU - Marjamaa, Annukka

AU - Kucera, Jan P.

AU - Laitinen-Forsblom, Päivi J.

AU - Lahtinen, Annukka M.

AU - Palotie, Aarno

AU - Kontula, Kimmo

AU - Toivonen, Lauri

AU - Abriel, Hugues

AU - Widen, Elisabeth

PY - 2014/12

Y1 - 2014/12

KW - arrhythmia (heart rhythm disorders)

KW - catecholaminergic polymorphic ventricular tachycardia

KW - exercise test

KW - genetic testing

KW - mutation

KW - SCN5A

KW - LONG QT SYNDROME

KW - CARDIAC SODIUM-CHANNEL

KW - BRUGADA-SYNDROME

KW - CA2+ SPARK

KW - IN-VITRO

KW - TACHYCARDIA

KW - MODEL

KW - DISEASE

KW - FAMILY

KW - ERYTHROMELALGIA

KW - 3121 Internal medicine

U2 - 10.1161/CIRCGENETICS.114.000703

DO - 10.1161/CIRCGENETICS.114.000703

M3 - Article

VL - 7

SP - 771-U111

JO - Circulation. Cardiovascular genetics

JF - Circulation. Cardiovascular genetics

SN - 1942-325X

IS - 6

ER -