Gata2, Nkx2-2 and Skor2 form a transcription factor network regulating development of a midbrain GABAergic neuron subtype with characteristics of REM-sleep regulatory neurons

Anna Kirjavainen; Parul Singh; Laura Lahti; Patricia Seja; Zoltan Lelkes; Aki Makkonen; Sami Kilpinen; Yuichi Ono; Marjo Salminen; Teemu Aitta-Aho; Tarja Stenberg; Svetlana Molchanova; Kaia Achim; Juha Partanen

doi:10.1242/dev.200937

Gata2, Nkx2-2 and Skor2 form a transcription factor network regulating development of a midbrain GABAergic neuron subtype with characteristics of REM-sleep regulatory neurons

Anna Kirjavainen, Parul Singh, Laura Lahti, Patricia Seja, Zoltan Lelkes, Aki Makkonen, Sami Kilpinen, Yuichi Ono, Marjo Salminen, Teemu Aitta-Aho, Tarja Stenberg, Svetlana Molchanova, Kaia Achim, Juha Partanen

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	200937
Journal	Development
Volume	149
Issue number	14
Number of pages	14
ISSN	0950-1991
DOIs	https://doi.org/10.1242/dev.200937 https://doi.org/10.1101/2022.01.05.473755
Publication status	Published - Jul 2022
MoE publication type	A1 Journal article-refereed

Fields of Science

Midbrain reticular formation
Deep mesencephalic nucleus
Periaqueductal gray
Neurogenesis
Transcription factor
Skor2
Nkx2-2
Gata2
REM sleep
Mouse
Rat
SUBLATERODORSAL NUCLEUS
DIFFERENTIATION
FATE
GENE
LOCALIZATION
WAKEFULNESS
EXPRESSION
IDENTITY
3112 Neurosciences

Access to Document

10.1242/dev.200937
10.1101/2022.01.05.473755Licence: CC BY-NC-ND

Cite this

Kirjavainen, A., Singh, P., Lahti, L., Seja, P., Lelkes, Z., Makkonen, A., Kilpinen, S., Ono, Y., Salminen, M., Aitta-Aho, T., Stenberg, T., Molchanova, S., Achim, K., & Partanen, J. (2022). Gata2, Nkx2-2 and Skor2 form a transcription factor network regulating development of a midbrain GABAergic neuron subtype with characteristics of REM-sleep regulatory neurons. Development, 149(14), Article 200937. https://doi.org/10.1242/dev.200937, https://doi.org/10.1101/2022.01.05.473755

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keywords = "Midbrain reticular formation, Deep mesencephalic nucleus, Periaqueductal gray, Neurogenesis, Transcription factor, Skor2, Nkx2-2, Gata2, REM sleep, Mouse, Rat, SUBLATERODORSAL NUCLEUS, DIFFERENTIATION, FATE, GENE, LOCALIZATION, WAKEFULNESS, EXPRESSION, IDENTITY, 3112 Neurosciences",

author = "Anna Kirjavainen and Parul Singh and Laura Lahti and Patricia Seja and Zoltan Lelkes and Aki Makkonen and Sami Kilpinen and Yuichi Ono and Marjo Salminen and Teemu Aitta-Aho and Tarja Stenberg and Svetlana Molchanova and Kaia Achim and Juha Partanen",

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Kirjavainen, A, Singh, P, Lahti, L, Seja, P, Lelkes, Z, Makkonen, A, Kilpinen, S, Ono, Y, Salminen, M , Aitta-Aho, T , Stenberg, T , Molchanova, S , Achim, K & Partanen, J 2022, 'Gata2, Nkx2-2 and Skor2 form a transcription factor network regulating development of a midbrain GABAergic neuron subtype with characteristics of REM-sleep regulatory neurons', Development, vol. 149, no. 14, 200937. https://doi.org/10.1242/dev.200937, https://doi.org/10.1101/2022.01.05.473755

TY - JOUR

T1 - Gata2, Nkx2-2 and Skor2 form a transcription factor network regulating development of a midbrain GABAergic neuron subtype with characteristics of REM-sleep regulatory neurons

AU - Kirjavainen, Anna

AU - Singh, Parul

AU - Lahti, Laura

AU - Seja, Patricia

AU - Lelkes, Zoltan

AU - Makkonen, Aki

AU - Kilpinen, Sami

AU - Ono, Yuichi

AU - Salminen, Marjo

AU - Aitta-Aho, Teemu

AU - Stenberg, Tarja

AU - Molchanova, Svetlana

AU - Achim, Kaia

AU - Partanen, Juha

PY - 2022/7

Y1 - 2022/7

KW - Midbrain reticular formation

KW - Deep mesencephalic nucleus

KW - Periaqueductal gray

KW - Neurogenesis

KW - Transcription factor

KW - Skor2

KW - Nkx2-2

KW - Gata2

KW - REM sleep

KW - Mouse

KW - Rat

KW - SUBLATERODORSAL NUCLEUS

KW - DIFFERENTIATION

KW - FATE

KW - GENE

KW - LOCALIZATION

KW - WAKEFULNESS

KW - EXPRESSION

KW - IDENTITY

KW - 3112 Neurosciences

U2 - 10.1242/dev.200937

DO - 10.1242/dev.200937

M3 - Article

SN - 0950-1991

VL - 149

JO - Development

JF - Development

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