Genetic architecture of circulating lipid levels

Ayse Demirkan; Najaf Amin; Aaron Isaacs; Marjo-Riitta Jarvelin; John B. Whitfield; Heinz-Erich Wichmann; Kirsten Ohm Kyvik; Igor Rudan; Christian Gieger; Andrew A. Hicks; Asa Johansson; Jouke-Jan Hottenga; Johannes J. Smith; Sarah H. Wild; Nancy L. Pedersen; Gonneke Willemsen; Massimo Mangino; Caroline Hayward; Andre G. Uitterlinden; Albert Hofman; Jacqueline Witteman; Grant W. Montgomery; Kirsi Hannele Pietiläinen; Taina Rantanen; Jaakko Kaprio; Angela Doering; Peter P. Pramstaller; Ulf Gyllensten; Eco J. C. de Geus; Brenda W. Penninx; James F. Wilson; Fernando Rivadeneria; Patrik K. E. Magnusson; Dorret I. Boomsma; Tim Spector; Harry Campbell; Birgit Hoehne; Nicholas G. Martin; Ben A. Oostra; Mark McCarthy; Leena Palotie; Yurii Aulchenko; Peter M. Visscher; Samuli Ripatti; A. Cecile J. W. Janssens; Cornelia M. van Duijn; ENGAGE CONSORTIUM

doi:10.1038/ejhg.2011.21

Genetic architecture of circulating lipid levels

Ayse Demirkan, Najaf Amin, Aaron Isaacs, Marjo-Riitta Jarvelin, John B. Whitfield, Heinz-Erich Wichmann, Kirsten Ohm Kyvik, Igor Rudan, Christian Gieger, Andrew A. Hicks, Asa Johansson, Jouke-Jan Hottenga, Johannes J. Smith, Sarah H. Wild, Nancy L. Pedersen, Gonneke Willemsen, Massimo Mangino, Caroline Hayward, Andre G. Uitterlinden, Albert HofmanJacqueline Witteman, Grant W. Montgomery, Kirsi Hannele Pietiläinen, Taina Rantanen, Jaakko Kaprio, Angela Doering, Peter P. Pramstaller, Ulf Gyllensten, Eco J. C. de Geus, Brenda W. Penninx, James F. Wilson, Fernando Rivadeneria, Patrik K. E. Magnusson, Dorret I. Boomsma, Tim Spector, Harry Campbell, Birgit Hoehne, Nicholas G. Martin, Ben A. Oostra, Mark McCarthy, Leena Palotie, Yurii Aulchenko, Peter M. Visscher, Samuli Ripatti, A. Cecile J. W. Janssens, Cornelia M. van Duijn, ENGAGE CONSORTIUM

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	European Journal of Human Genetics
Volume	19
Issue number	7
Pages (from-to)	813-819
Number of pages	7
ISSN	1018-4813
DOIs	https://doi.org/10.1038/ejhg.2011.21
Publication status	Published - 2011
MoE publication type	A1 Journal article-refereed

Fields of Science

serum lipids
polygenic
genome-wide association
polygenic score
pathway analysis
DENSITY-LIPOPROTEIN CHOLESTEROL
GENOME-WIDE ASSOCIATION
CORONARY-ARTERY-DISEASE
HEART-DISEASE
PLASMA-LIPIDS
POPULATION
LOCI
RISK
CONTRIBUTE
MUTATIONS
3142 Public health care science, environmental and occupational health

Access to Document

10.1038/ejhg.2011.21

Cite this

Demirkan, A., Amin, N., Isaacs, A., Jarvelin, M-R., Whitfield, J. B., Wichmann, H-E., Kyvik, K. O., Rudan, I., Gieger, C., Hicks, A. A., Johansson, A., Hottenga, J-J., Smith, J. J., Wild, S. H., Pedersen, N. L., Willemsen, G., Mangino, M., Hayward, C., Uitterlinden, A. G., ... ENGAGE CONSORTIUM (2011). Genetic architecture of circulating lipid levels. European Journal of Human Genetics, 19(7), 813-819. https://doi.org/10.1038/ejhg.2011.21

Demirkan, Ayse ; Amin, Najaf ; Isaacs, Aaron ; Jarvelin, Marjo-Riitta ; Whitfield, John B. ; Wichmann, Heinz-Erich ; Kyvik, Kirsten Ohm ; Rudan, Igor ; Gieger, Christian ; Hicks, Andrew A. ; Johansson, Asa ; Hottenga, Jouke-Jan ; Smith, Johannes J. ; Wild, Sarah H. ; Pedersen, Nancy L. ; Willemsen, Gonneke ; Mangino, Massimo ; Hayward, Caroline ; Uitterlinden, Andre G. ; Hofman, Albert ; Witteman, Jacqueline ; Montgomery, Grant W. ; Pietiläinen, Kirsi Hannele ; Rantanen, Taina ; Kaprio, Jaakko ; Doering, Angela ; Pramstaller, Peter P. ; Gyllensten, Ulf ; de Geus, Eco J. C. ; Penninx, Brenda W. ; Wilson, James F. ; Rivadeneria, Fernando ; Magnusson, Patrik K. E. ; Boomsma, Dorret I. ; Spector, Tim ; Campbell, Harry ; Hoehne, Birgit ; Martin, Nicholas G. ; Oostra, Ben A. ; McCarthy, Mark ; Palotie, Leena ; Aulchenko, Yurii ; Visscher, Peter M. ; Ripatti, Samuli ; Janssens, A. Cecile J. W. ; van Duijn, Cornelia M. ; ENGAGE CONSORTIUM. / Genetic architecture of circulating lipid levels. In: European Journal of Human Genetics. 2011 ; Vol. 19, No. 7. pp. 813-819.

@article{5030c905f88b4f099c0d1f522b290e8e,

title = "Genetic architecture of circulating lipid levels",

keywords = "serum lipids, polygenic, genome-wide association, polygenic score, pathway analysis, DENSITY-LIPOPROTEIN CHOLESTEROL, GENOME-WIDE ASSOCIATION, CORONARY-ARTERY-DISEASE, HEART-DISEASE, PLASMA-LIPIDS, POPULATION, LOCI, RISK, CONTRIBUTE, MUTATIONS, 3142 Public health care science, environmental and occupational health",

author = "Ayse Demirkan and Najaf Amin and Aaron Isaacs and Marjo-Riitta Jarvelin and Whitfield, {John B.} and Heinz-Erich Wichmann and Kyvik, {Kirsten Ohm} and Igor Rudan and Christian Gieger and Hicks, {Andrew A.} and Asa Johansson and Jouke-Jan Hottenga and Smith, {Johannes J.} and Wild, {Sarah H.} and Pedersen, {Nancy L.} and Gonneke Willemsen and Massimo Mangino and Caroline Hayward and Uitterlinden, {Andre G.} and Albert Hofman and Jacqueline Witteman and Montgomery, {Grant W.} and Pietil{\"a}inen, {Kirsi Hannele} and Taina Rantanen and Jaakko Kaprio and Angela Doering and Pramstaller, {Peter P.} and Ulf Gyllensten and {de Geus}, {Eco J. C.} and Penninx, {Brenda W.} and Wilson, {James F.} and Fernando Rivadeneria and Magnusson, {Patrik K. E.} and Boomsma, {Dorret I.} and Tim Spector and Harry Campbell and Birgit Hoehne and Martin, {Nicholas G.} and Oostra, {Ben A.} and Mark McCarthy and Leena Palotie and Yurii Aulchenko and Visscher, {Peter M.} and Samuli Ripatti and Janssens, {A. Cecile J. W.} and {van Duijn}, {Cornelia M.} and {ENGAGE CONSORTIUM}",

year = "2011",

doi = "10.1038/ejhg.2011.21",

language = "English",

volume = "19",

pages = "813--819",

journal = "European Journal of Human Genetics",

issn = "1018-4813",

publisher = "Nature Publishing Group",

number = "7",

}

Demirkan, A, Amin, N, Isaacs, A, Jarvelin, M-R, Whitfield, JB, Wichmann, H-E, Kyvik, KO, Rudan, I, Gieger, C, Hicks, AA, Johansson, A, Hottenga, J-J, Smith, JJ, Wild, SH, Pedersen, NL, Willemsen, G, Mangino, M, Hayward, C, Uitterlinden, AG, Hofman, A, Witteman, J, Montgomery, GW, Pietiläinen, KH, Rantanen, T, Kaprio, J, Doering, A, Pramstaller, PP, Gyllensten, U, de Geus, EJC, Penninx, BW, Wilson, JF, Rivadeneria, F, Magnusson, PKE, Boomsma, DI, Spector, T, Campbell, H, Hoehne, B, Martin, NG, Oostra, BA, McCarthy, M, Palotie, L, Aulchenko, Y, Visscher, PM, Ripatti, S, Janssens, ACJW, van Duijn, CM & ENGAGE CONSORTIUM 2011, 'Genetic architecture of circulating lipid levels', European Journal of Human Genetics, vol. 19, no. 7, pp. 813-819. https://doi.org/10.1038/ejhg.2011.21

Genetic architecture of circulating lipid levels. / Demirkan, Ayse; Amin, Najaf; Isaacs, Aaron; Jarvelin, Marjo-Riitta; Whitfield, John B.; Wichmann, Heinz-Erich; Kyvik, Kirsten Ohm; Rudan, Igor; Gieger, Christian; Hicks, Andrew A.; Johansson, Asa; Hottenga, Jouke-Jan; Smith, Johannes J.; Wild, Sarah H.; Pedersen, Nancy L.; Willemsen, Gonneke; Mangino, Massimo; Hayward, Caroline; Uitterlinden, Andre G.; Hofman, Albert; Witteman, Jacqueline; Montgomery, Grant W.; Pietiläinen, Kirsi Hannele; Rantanen, Taina; Kaprio, Jaakko; Doering, Angela; Pramstaller, Peter P.; Gyllensten, Ulf; de Geus, Eco J. C.; Penninx, Brenda W.; Wilson, James F.; Rivadeneria, Fernando; Magnusson, Patrik K. E.; Boomsma, Dorret I.; Spector, Tim; Campbell, Harry; Hoehne, Birgit; Martin, Nicholas G.; Oostra, Ben A.; McCarthy, Mark; Palotie, Leena; Aulchenko, Yurii; Visscher, Peter M.; Ripatti, Samuli; Janssens, A. Cecile J. W.; van Duijn, Cornelia M.; ENGAGE CONSORTIUM.

In: European Journal of Human Genetics, Vol. 19, No. 7, 2011, p. 813-819.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - Genetic architecture of circulating lipid levels

AU - Demirkan, Ayse

AU - Amin, Najaf

AU - Isaacs, Aaron

AU - Jarvelin, Marjo-Riitta

AU - Whitfield, John B.

AU - Wichmann, Heinz-Erich

AU - Kyvik, Kirsten Ohm

AU - Rudan, Igor

AU - Gieger, Christian

AU - Hicks, Andrew A.

AU - Johansson, Asa

AU - Hottenga, Jouke-Jan

AU - Smith, Johannes J.

AU - Wild, Sarah H.

AU - Pedersen, Nancy L.

AU - Willemsen, Gonneke

AU - Mangino, Massimo

AU - Hayward, Caroline

AU - Uitterlinden, Andre G.

AU - Hofman, Albert

AU - Witteman, Jacqueline

AU - Montgomery, Grant W.

AU - Pietiläinen, Kirsi Hannele

AU - Rantanen, Taina

AU - Kaprio, Jaakko

AU - Doering, Angela

AU - Pramstaller, Peter P.

AU - Gyllensten, Ulf

AU - de Geus, Eco J. C.

AU - Penninx, Brenda W.

AU - Wilson, James F.

AU - Rivadeneria, Fernando

AU - Magnusson, Patrik K. E.

AU - Boomsma, Dorret I.

AU - Spector, Tim

AU - Campbell, Harry

AU - Hoehne, Birgit

AU - Martin, Nicholas G.

AU - Oostra, Ben A.

AU - McCarthy, Mark

AU - Palotie, Leena

AU - Aulchenko, Yurii

AU - Visscher, Peter M.

AU - Ripatti, Samuli

AU - Janssens, A. Cecile J. W.

AU - van Duijn, Cornelia M.

AU - ENGAGE CONSORTIUM

PY - 2011

Y1 - 2011

KW - serum lipids

KW - polygenic

KW - genome-wide association

KW - polygenic score

KW - pathway analysis

KW - DENSITY-LIPOPROTEIN CHOLESTEROL

KW - GENOME-WIDE ASSOCIATION

KW - CORONARY-ARTERY-DISEASE

KW - HEART-DISEASE

KW - PLASMA-LIPIDS

KW - POPULATION

KW - LOCI

KW - RISK

KW - CONTRIBUTE

KW - MUTATIONS

KW - 3142 Public health care science, environmental and occupational health

U2 - 10.1038/ejhg.2011.21

DO - 10.1038/ejhg.2011.21

M3 - Article

VL - 19

SP - 813

EP - 819

JO - European Journal of Human Genetics

JF - European Journal of Human Genetics

SN - 1018-4813

IS - 7

ER -