Genetic Associations and Architecture of Asthma-COPD Overlap

Catherine John; Anna L. Guyatt; Nick Shrine; Richard Packer; Thorunn A. Olafsdottir; Jiangyuan Liu; Lystra P. Hayden; Su H. Chu; Jukka T. Koskela; Jian'an Luan; Xingnan Li; Natalie Terzikhan; Hanfei Xu; Traci M. Bartz; Hans Petersen; Shuguang Leng; Steven A. Belinsky; Aivaras Cepelis; Ana I. Hernandez Cordero; Ma'en Obeidat; Gudmar Thorleifsson; Deborah A. Meyers; Eugene R. Bleecker; Lori C. Sakoda; Carlos Iribarren; Yohannes Tesfaigzi; Sina A. Gharib; Josee Dupuis; Guy Brusselle; Lies Lahousse; Victor E. Ortega; Ingileif Jonsdottir; Don D. Sin; Yohan Bosse; Maarten van den Berge; David Nickle; Jennifer K. Quint; Ian Sayers; Ian P. Hall; Claudia Langenberg; Samuli Ripatti; Tarja Laitinen; Ann C. Wu; Jessica Lasky-Su; Per Bakke; Amund Gulsvik; Craig P. Hersh; Caroline Hayward; Arnulf Langhammer; Ben Brumpton; Kari Stefansson; Michael H. Cho; Louise Wain; Martin D. Tobin

doi:10.1016/j.chest.2021.12.674

Genetic Associations and Architecture of Asthma-COPD Overlap

Catherine John, Anna L. Guyatt, Nick Shrine, Richard Packer, Thorunn A. Olafsdottir, Jiangyuan Liu, Lystra P. Hayden, Su H. Chu, Jukka T. Koskela, Jian'an Luan, Xingnan Li, Natalie Terzikhan, Hanfei Xu, Traci M. Bartz, Hans Petersen, Shuguang Leng, Steven A. Belinsky, Aivaras Cepelis, Ana I. Hernandez Cordero, Ma'en ObeidatGudmar Thorleifsson, Deborah A. Meyers, Eugene R. Bleecker, Lori C. Sakoda, Carlos Iribarren, Yohannes Tesfaigzi, Sina A. Gharib, Josee Dupuis, Guy Brusselle, Lies Lahousse, Victor E. Ortega, Ingileif Jonsdottir, Don D. Sin, Yohan Bosse, Maarten van den Berge, David Nickle, Jennifer K. Quint, Ian Sayers, Ian P. Hall, Claudia Langenberg, Samuli Ripatti, Tarja Laitinen, Ann C. Wu, Jessica Lasky-Su, Per Bakke, Amund Gulsvik, Craig P. Hersh, Caroline Hayward, Arnulf Langhammer, Ben Brumpton, Kari Stefansson, Michael H. Cho, Louise Wain, Martin D. Tobin

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Chest
Volume	161
Issue number	5
Pages (from-to)	1155-1166
Number of pages	12
ISSN	0012-3692
DOIs	https://doi.org/10.1016/j.chest.2021.12.674
Publication status	Published - May 2022
MoE publication type	A1 Journal article-refereed

Fields of Science

asthma
COPD
epidemiology
genome-wide association study
spirometry
OBSTRUCTIVE PULMONARY-DISEASE
GENOME-WIDE ASSOCIATION
BLOOD EOSINOPHIL COUNT
HAY-FEVER
RISK
LOCI
EXACERBATIONS
HERITABILITY
3121 General medicine, internal medicine and other clinical medicine
3126 Surgery, anesthesiology, intensive care, radiology

Access to Document

10.1016/j.chest.2021.12.674

PIIS0012369222001982Final published version, 658 KBLicence: CC BY

Cite this

John, C., Guyatt, A. L., Shrine, N., Packer, R., Olafsdottir, T. A., Liu, J., Hayden, L. P., Chu, S. H., Koskela, J. T., Luan, J., Li, X., Terzikhan, N., Xu, H., Bartz, T. M., Petersen, H., Leng, S., Belinsky, S. A., Cepelis, A., Cordero, A. I. H., ... Tobin, M. D. (2022). Genetic Associations and Architecture of Asthma-COPD Overlap. Chest, 161(5), 1155-1166. https://doi.org/10.1016/j.chest.2021.12.674

@article{14007c1b228240d3b74b5f2678313ed8,

title = "Genetic Associations and Architecture of Asthma-COPD Overlap",

keywords = "asthma, COPD, epidemiology, genome-wide association study, spirometry, OBSTRUCTIVE PULMONARY-DISEASE, GENOME-WIDE ASSOCIATION, BLOOD EOSINOPHIL COUNT, HAY-FEVER, RISK, LOCI, EXACERBATIONS, HERITABILITY, 3121 General medicine, internal medicine and other clinical medicine, 3126 Surgery, anesthesiology, intensive care, radiology",

author = "Catherine John and Guyatt, {Anna L.} and Nick Shrine and Richard Packer and Olafsdottir, {Thorunn A.} and Jiangyuan Liu and Hayden, {Lystra P.} and Chu, {Su H.} and Koskela, {Jukka T.} and Jian'an Luan and Xingnan Li and Natalie Terzikhan and Hanfei Xu and Bartz, {Traci M.} and Hans Petersen and Shuguang Leng and Belinsky, {Steven A.} and Aivaras Cepelis and Cordero, {Ana I. Hernandez} and Ma'en Obeidat and Gudmar Thorleifsson and Meyers, {Deborah A.} and Bleecker, {Eugene R.} and Sakoda, {Lori C.} and Carlos Iribarren and Yohannes Tesfaigzi and Gharib, {Sina A.} and Josee Dupuis and Guy Brusselle and Lies Lahousse and Ortega, {Victor E.} and Ingileif Jonsdottir and Sin, {Don D.} and Yohan Bosse and {van den Berge}, Maarten and David Nickle and Quint, {Jennifer K.} and Ian Sayers and Hall, {Ian P.} and Claudia Langenberg and Samuli Ripatti and Tarja Laitinen and Wu, {Ann C.} and Jessica Lasky-Su and Per Bakke and Amund Gulsvik and Hersh, {Craig P.} and Caroline Hayward and Arnulf Langhammer and Ben Brumpton and Kari Stefansson and Cho, {Michael H.} and Louise Wain and Tobin, {Martin D.}",

year = "2022",

month = may,

doi = "10.1016/j.chest.2021.12.674",

language = "English",

volume = "161",

pages = "1155--1166",

journal = "Chest",

issn = "0012-3692",

publisher = "Elsevier Scientific Publ. Co",

number = "5",

}

John, C, Guyatt, AL, Shrine, N, Packer, R, Olafsdottir, TA, Liu, J, Hayden, LP, Chu, SH, Koskela, JT, Luan, J, Li, X, Terzikhan, N, Xu, H, Bartz, TM, Petersen, H, Leng, S, Belinsky, SA, Cepelis, A, Cordero, AIH, Obeidat, M, Thorleifsson, G, Meyers, DA, Bleecker, ER, Sakoda, LC, Iribarren, C, Tesfaigzi, Y, Gharib, SA, Dupuis, J, Brusselle, G, Lahousse, L, Ortega, VE, Jonsdottir, I, Sin, DD, Bosse, Y, van den Berge, M, Nickle, D, Quint, JK, Sayers, I, Hall, IP, Langenberg, C, Ripatti, S, Laitinen, T, Wu, AC, Lasky-Su, J, Bakke, P, Gulsvik, A, Hersh, CP, Hayward, C, Langhammer, A, Brumpton, B, Stefansson, K, Cho, MH, Wain, L & Tobin, MD 2022, 'Genetic Associations and Architecture of Asthma-COPD Overlap', Chest, vol. 161, no. 5, pp. 1155-1166. https://doi.org/10.1016/j.chest.2021.12.674

TY - JOUR

T1 - Genetic Associations and Architecture of Asthma-COPD Overlap

AU - John, Catherine

AU - Guyatt, Anna L.

AU - Shrine, Nick

AU - Packer, Richard

AU - Olafsdottir, Thorunn A.

AU - Liu, Jiangyuan

AU - Hayden, Lystra P.

AU - Chu, Su H.

AU - Koskela, Jukka T.

AU - Luan, Jian'an

AU - Li, Xingnan

AU - Terzikhan, Natalie

AU - Xu, Hanfei

AU - Bartz, Traci M.

AU - Petersen, Hans

AU - Leng, Shuguang

AU - Belinsky, Steven A.

AU - Cepelis, Aivaras

AU - Cordero, Ana I. Hernandez

AU - Obeidat, Ma'en

AU - Thorleifsson, Gudmar

AU - Meyers, Deborah A.

AU - Bleecker, Eugene R.

AU - Sakoda, Lori C.

AU - Iribarren, Carlos

AU - Tesfaigzi, Yohannes

AU - Gharib, Sina A.

AU - Dupuis, Josee

AU - Brusselle, Guy

AU - Lahousse, Lies

AU - Ortega, Victor E.

AU - Jonsdottir, Ingileif

AU - Sin, Don D.

AU - Bosse, Yohan

AU - van den Berge, Maarten

AU - Nickle, David

AU - Quint, Jennifer K.

AU - Sayers, Ian

AU - Hall, Ian P.

AU - Langenberg, Claudia

AU - Ripatti, Samuli

AU - Laitinen, Tarja

AU - Wu, Ann C.

AU - Lasky-Su, Jessica

AU - Bakke, Per

AU - Gulsvik, Amund

AU - Hersh, Craig P.

AU - Hayward, Caroline

AU - Langhammer, Arnulf

AU - Brumpton, Ben

AU - Stefansson, Kari

AU - Cho, Michael H.

AU - Wain, Louise

AU - Tobin, Martin D.

PY - 2022/5

Y1 - 2022/5

KW - asthma

KW - COPD

KW - epidemiology

KW - genome-wide association study

KW - spirometry

KW - OBSTRUCTIVE PULMONARY-DISEASE

KW - GENOME-WIDE ASSOCIATION

KW - BLOOD EOSINOPHIL COUNT

KW - HAY-FEVER

KW - RISK

KW - LOCI

KW - EXACERBATIONS

KW - HERITABILITY

KW - 3121 General medicine, internal medicine and other clinical medicine

KW - 3126 Surgery, anesthesiology, intensive care, radiology

U2 - 10.1016/j.chest.2021.12.674

DO - 10.1016/j.chest.2021.12.674

M3 - Article

VL - 161

SP - 1155

EP - 1166

JO - Chest

JF - Chest

SN - 0012-3692

IS - 5

ER -