Genetic Data from Nearly 63,000 Women of European Descent Predicts DNA Methylation Biomarkers and Epithelial Ovarian Cancer Risk

Yaohua Yang, Lang Wu, Xiang Shu, Yingchang Lu, Xiao-Ou Shu, Qiuyin Cai, Alicia Beeghly-Fadiel, Bingshan Li, Fei Ye, Andrew Berchuck, Hoda Anton-Culver, Susana Banerjee, Javier Benitez, Line Bjorge, James D. Brenton, Ralf Butzow, Ian G. Campbell, Jenny Chang-Claude, Kexin Chen, Linda S. CookDaniel W. Cramer, Anna defazio, Joe Dennis, Jennifer A. Doherty, Thilo Doerk, Diana M. Eccles, Digna Velez Edwards, Peter A. Fasching, Renee T. Fortner, Simon A. Gayther, Graham G. Giles, Rosalind M. Glasspool, Ellen L. Goode, Marc T. Goodman, Jacek Gronwald, Holly R. Harris, Florian Heitz, Michelle A. Hildebrandt, Estrid Hogdall, Claus K. Hogdall, David G. Huntsman, Siddhartha P. Kar, Beth Y. Karlan, Linda E. Kelemen, Lambertus A. Kiemeney, Susanne K. Kjaer, Anita Koushik, Diether Lambrechts, Nhu D. Le, Douglas A. Levine, Leon F. Massuger, Keitaro Matsuo, Taymaa May, Iain A. McNeish, Usha Menon, Francesmary Modugno, Alvaro N. Monteiro, Patricia G. Moorman, Kirsten B. Moysich, Roberta B. Ness, Heli Nevanlinna, Hakan Olsson, N. Charlotte Onland-Moret, Sue K. Park, James Paul, Celeste L. Pearce, Tanja Pejovic, Catherine M. Phelan, Malcolm C. Pike, Susan J. Ramus, Elio Riboli, Cristina Rodriguez-Antona, Isabelle Romieu, Dale P. Sandler, Joellen M. Schildkraut, Veronica W. Setiawan, Kang Shan, Nadeem Siddiqui, Weiva Sieh, Meir J. Stampfer, Rebecca Sutphen, Anthony J. Swerdlow, Lukasz M. Szafron, Soo Hwang Teo, Shelley S. Tworoger, Jonathan P. Tyrer, Penelope M. Webb, Nicolas Wentzensen, Emily White, Walter C. Willett, Alicja Wolk, Yin Ling Woo, Anna H. Wu, Li Yan, Drakoulis Yannoukakos, Georgia Chenevix-Trench, Thomas A. Sellers, Paul D. P. Pharoah, Wei Zheng, Jirong Long

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalCancer Research
Volume79
Issue number3
Pages (from-to)505-517
Number of pages13
ISSN0008-5472
DOIs
Publication statusPublished - 1 Feb 2019
MoE publication typeA1 Journal article-refereed

Fields of Science

  • SUSCEPTIBILITY LOCI
  • WIDE ASSOCIATION
  • DISEASE
  • MAPT
  • PROTEIN
  • TISSUE
  • GWAS
  • IDENTIFICATION
  • VARIANTS
  • THERAPY
  • 3122 Cancers

Cite this

Yang, Yaohua ; Wu, Lang ; Shu, Xiang ; Lu, Yingchang ; Shu, Xiao-Ou ; Cai, Qiuyin ; Beeghly-Fadiel, Alicia ; Li, Bingshan ; Ye, Fei ; Berchuck, Andrew ; Anton-Culver, Hoda ; Banerjee, Susana ; Benitez, Javier ; Bjorge, Line ; Brenton, James D. ; Butzow, Ralf ; Campbell, Ian G. ; Chang-Claude, Jenny ; Chen, Kexin ; Cook, Linda S. ; Cramer, Daniel W. ; defazio, Anna ; Dennis, Joe ; Doherty, Jennifer A. ; Doerk, Thilo ; Eccles, Diana M. ; Edwards, Digna Velez ; Fasching, Peter A. ; Fortner, Renee T. ; Gayther, Simon A. ; Giles, Graham G. ; Glasspool, Rosalind M. ; Goode, Ellen L. ; Goodman, Marc T. ; Gronwald, Jacek ; Harris, Holly R. ; Heitz, Florian ; Hildebrandt, Michelle A. ; Hogdall, Estrid ; Hogdall, Claus K. ; Huntsman, David G. ; Kar, Siddhartha P. ; Karlan, Beth Y. ; Kelemen, Linda E. ; Kiemeney, Lambertus A. ; Kjaer, Susanne K. ; Koushik, Anita ; Lambrechts, Diether ; Le, Nhu D. ; Levine, Douglas A. ; Massuger, Leon F. ; Matsuo, Keitaro ; May, Taymaa ; McNeish, Iain A. ; Menon, Usha ; Modugno, Francesmary ; Monteiro, Alvaro N. ; Moorman, Patricia G. ; Moysich, Kirsten B. ; Ness, Roberta B. ; Nevanlinna, Heli ; Olsson, Hakan ; Onland-Moret, N. Charlotte ; Park, Sue K. ; Paul, James ; Pearce, Celeste L. ; Pejovic, Tanja ; Phelan, Catherine M. ; Pike, Malcolm C. ; Ramus, Susan J. ; Riboli, Elio ; Rodriguez-Antona, Cristina ; Romieu, Isabelle ; Sandler, Dale P. ; Schildkraut, Joellen M. ; Setiawan, Veronica W. ; Shan, Kang ; Siddiqui, Nadeem ; Sieh, Weiva ; Stampfer, Meir J. ; Sutphen, Rebecca ; Swerdlow, Anthony J. ; Szafron, Lukasz M. ; Teo, Soo Hwang ; Tworoger, Shelley S. ; Tyrer, Jonathan P. ; Webb, Penelope M. ; Wentzensen, Nicolas ; White, Emily ; Willett, Walter C. ; Wolk, Alicja ; Woo, Yin Ling ; Wu, Anna H. ; Yan, Li ; Yannoukakos, Drakoulis ; Chenevix-Trench, Georgia ; Sellers, Thomas A. ; Pharoah, Paul D. P. ; Zheng, Wei ; Long, Jirong. / Genetic Data from Nearly 63,000 Women of European Descent Predicts DNA Methylation Biomarkers and Epithelial Ovarian Cancer Risk. In: Cancer Research. 2019 ; Vol. 79, No. 3. pp. 505-517.
@article{4d481a3579df477c92db8e5715039dec,
title = "Genetic Data from Nearly 63,000 Women of European Descent Predicts DNA Methylation Biomarkers and Epithelial Ovarian Cancer Risk",
keywords = "SUSCEPTIBILITY LOCI, WIDE ASSOCIATION, DISEASE, MAPT, PROTEIN, TISSUE, GWAS, IDENTIFICATION, VARIANTS, THERAPY, 3122 Cancers",
author = "Yaohua Yang and Lang Wu and Xiang Shu and Yingchang Lu and Xiao-Ou Shu and Qiuyin Cai and Alicia Beeghly-Fadiel and Bingshan Li and Fei Ye and Andrew Berchuck and Hoda Anton-Culver and Susana Banerjee and Javier Benitez and Line Bjorge and Brenton, {James D.} and Ralf Butzow and Campbell, {Ian G.} and Jenny Chang-Claude and Kexin Chen and Cook, {Linda S.} and Cramer, {Daniel W.} and Anna defazio and Joe Dennis and Doherty, {Jennifer A.} and Thilo Doerk and Eccles, {Diana M.} and Edwards, {Digna Velez} and Fasching, {Peter A.} and Fortner, {Renee T.} and Gayther, {Simon A.} and Giles, {Graham G.} and Glasspool, {Rosalind M.} and Goode, {Ellen L.} and Goodman, {Marc T.} and Jacek Gronwald and Harris, {Holly R.} and Florian Heitz and Hildebrandt, {Michelle A.} and Estrid Hogdall and Hogdall, {Claus K.} and Huntsman, {David G.} and Kar, {Siddhartha P.} and Karlan, {Beth Y.} and Kelemen, {Linda E.} and Kiemeney, {Lambertus A.} and Kjaer, {Susanne K.} and Anita Koushik and Diether Lambrechts and Le, {Nhu D.} and Levine, {Douglas A.} and Massuger, {Leon F.} and Keitaro Matsuo and Taymaa May and McNeish, {Iain A.} and Usha Menon and Francesmary Modugno and Monteiro, {Alvaro N.} and Moorman, {Patricia G.} and Moysich, {Kirsten B.} and Ness, {Roberta B.} and Heli Nevanlinna and Hakan Olsson and Onland-Moret, {N. Charlotte} and Park, {Sue K.} and James Paul and Pearce, {Celeste L.} and Tanja Pejovic and Phelan, {Catherine M.} and Pike, {Malcolm C.} and Ramus, {Susan J.} and Elio Riboli and Cristina Rodriguez-Antona and Isabelle Romieu and Sandler, {Dale P.} and Schildkraut, {Joellen M.} and Setiawan, {Veronica W.} and Kang Shan and Nadeem Siddiqui and Weiva Sieh and Stampfer, {Meir J.} and Rebecca Sutphen and Swerdlow, {Anthony J.} and Szafron, {Lukasz M.} and Teo, {Soo Hwang} and Tworoger, {Shelley S.} and Tyrer, {Jonathan P.} and Webb, {Penelope M.} and Nicolas Wentzensen and Emily White and Willett, {Walter C.} and Alicja Wolk and Woo, {Yin Ling} and Wu, {Anna H.} and Li Yan and Drakoulis Yannoukakos and Georgia Chenevix-Trench and Sellers, {Thomas A.} and Pharoah, {Paul D. P.} and Wei Zheng and Jirong Long",
year = "2019",
month = "2",
day = "1",
doi = "10.1158/0008-5472.CAN-18-2726",
language = "English",
volume = "79",
pages = "505--517",
journal = "Cancer Research",
issn = "0008-5472",
publisher = "American Association for Cancer Research",
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}

Yang, Y, Wu, L, Shu, X, Lu, Y, Shu, X-O, Cai, Q, Beeghly-Fadiel, A, Li, B, Ye, F, Berchuck, A, Anton-Culver, H, Banerjee, S, Benitez, J, Bjorge, L, Brenton, JD, Butzow, R, Campbell, IG, Chang-Claude, J, Chen, K, Cook, LS, Cramer, DW, defazio, A, Dennis, J, Doherty, JA, Doerk, T, Eccles, DM, Edwards, DV, Fasching, PA, Fortner, RT, Gayther, SA, Giles, GG, Glasspool, RM, Goode, EL, Goodman, MT, Gronwald, J, Harris, HR, Heitz, F, Hildebrandt, MA, Hogdall, E, Hogdall, CK, Huntsman, DG, Kar, SP, Karlan, BY, Kelemen, LE, Kiemeney, LA, Kjaer, SK, Koushik, A, Lambrechts, D, Le, ND, Levine, DA, Massuger, LF, Matsuo, K, May, T, McNeish, IA, Menon, U, Modugno, F, Monteiro, AN, Moorman, PG, Moysich, KB, Ness, RB, Nevanlinna, H, Olsson, H, Onland-Moret, NC, Park, SK, Paul, J, Pearce, CL, Pejovic, T, Phelan, CM, Pike, MC, Ramus, SJ, Riboli, E, Rodriguez-Antona, C, Romieu, I, Sandler, DP, Schildkraut, JM, Setiawan, VW, Shan, K, Siddiqui, N, Sieh, W, Stampfer, MJ, Sutphen, R, Swerdlow, AJ, Szafron, LM, Teo, SH, Tworoger, SS, Tyrer, JP, Webb, PM, Wentzensen, N, White, E, Willett, WC, Wolk, A, Woo, YL, Wu, AH, Yan, L, Yannoukakos, D, Chenevix-Trench, G, Sellers, TA, Pharoah, PDP, Zheng, W & Long, J 2019, 'Genetic Data from Nearly 63,000 Women of European Descent Predicts DNA Methylation Biomarkers and Epithelial Ovarian Cancer Risk', Cancer Research, vol. 79, no. 3, pp. 505-517. https://doi.org/10.1158/0008-5472.CAN-18-2726

Genetic Data from Nearly 63,000 Women of European Descent Predicts DNA Methylation Biomarkers and Epithelial Ovarian Cancer Risk. / Yang, Yaohua; Wu, Lang; Shu, Xiang; Lu, Yingchang; Shu, Xiao-Ou; Cai, Qiuyin; Beeghly-Fadiel, Alicia; Li, Bingshan; Ye, Fei; Berchuck, Andrew; Anton-Culver, Hoda; Banerjee, Susana; Benitez, Javier; Bjorge, Line; Brenton, James D.; Butzow, Ralf; Campbell, Ian G.; Chang-Claude, Jenny; Chen, Kexin; Cook, Linda S.; Cramer, Daniel W.; defazio, Anna; Dennis, Joe; Doherty, Jennifer A.; Doerk, Thilo; Eccles, Diana M.; Edwards, Digna Velez; Fasching, Peter A.; Fortner, Renee T.; Gayther, Simon A.; Giles, Graham G.; Glasspool, Rosalind M.; Goode, Ellen L.; Goodman, Marc T.; Gronwald, Jacek; Harris, Holly R.; Heitz, Florian; Hildebrandt, Michelle A.; Hogdall, Estrid; Hogdall, Claus K.; Huntsman, David G.; Kar, Siddhartha P.; Karlan, Beth Y.; Kelemen, Linda E.; Kiemeney, Lambertus A.; Kjaer, Susanne K.; Koushik, Anita; Lambrechts, Diether; Le, Nhu D.; Levine, Douglas A.; Massuger, Leon F.; Matsuo, Keitaro; May, Taymaa; McNeish, Iain A.; Menon, Usha; Modugno, Francesmary; Monteiro, Alvaro N.; Moorman, Patricia G.; Moysich, Kirsten B.; Ness, Roberta B.; Nevanlinna, Heli; Olsson, Hakan; Onland-Moret, N. Charlotte; Park, Sue K.; Paul, James; Pearce, Celeste L.; Pejovic, Tanja; Phelan, Catherine M.; Pike, Malcolm C.; Ramus, Susan J.; Riboli, Elio; Rodriguez-Antona, Cristina; Romieu, Isabelle; Sandler, Dale P.; Schildkraut, Joellen M.; Setiawan, Veronica W.; Shan, Kang; Siddiqui, Nadeem; Sieh, Weiva; Stampfer, Meir J.; Sutphen, Rebecca; Swerdlow, Anthony J.; Szafron, Lukasz M.; Teo, Soo Hwang; Tworoger, Shelley S.; Tyrer, Jonathan P.; Webb, Penelope M.; Wentzensen, Nicolas; White, Emily; Willett, Walter C.; Wolk, Alicja; Woo, Yin Ling; Wu, Anna H.; Yan, Li; Yannoukakos, Drakoulis; Chenevix-Trench, Georgia; Sellers, Thomas A.; Pharoah, Paul D. P.; Zheng, Wei; Long, Jirong.

In: Cancer Research, Vol. 79, No. 3, 01.02.2019, p. 505-517.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Genetic Data from Nearly 63,000 Women of European Descent Predicts DNA Methylation Biomarkers and Epithelial Ovarian Cancer Risk

AU - Yang, Yaohua

AU - Wu, Lang

AU - Shu, Xiang

AU - Lu, Yingchang

AU - Shu, Xiao-Ou

AU - Cai, Qiuyin

AU - Beeghly-Fadiel, Alicia

AU - Li, Bingshan

AU - Ye, Fei

AU - Berchuck, Andrew

AU - Anton-Culver, Hoda

AU - Banerjee, Susana

AU - Benitez, Javier

AU - Bjorge, Line

AU - Brenton, James D.

AU - Butzow, Ralf

AU - Campbell, Ian G.

AU - Chang-Claude, Jenny

AU - Chen, Kexin

AU - Cook, Linda S.

AU - Cramer, Daniel W.

AU - defazio, Anna

AU - Dennis, Joe

AU - Doherty, Jennifer A.

AU - Doerk, Thilo

AU - Eccles, Diana M.

AU - Edwards, Digna Velez

AU - Fasching, Peter A.

AU - Fortner, Renee T.

AU - Gayther, Simon A.

AU - Giles, Graham G.

AU - Glasspool, Rosalind M.

AU - Goode, Ellen L.

AU - Goodman, Marc T.

AU - Gronwald, Jacek

AU - Harris, Holly R.

AU - Heitz, Florian

AU - Hildebrandt, Michelle A.

AU - Hogdall, Estrid

AU - Hogdall, Claus K.

AU - Huntsman, David G.

AU - Kar, Siddhartha P.

AU - Karlan, Beth Y.

AU - Kelemen, Linda E.

AU - Kiemeney, Lambertus A.

AU - Kjaer, Susanne K.

AU - Koushik, Anita

AU - Lambrechts, Diether

AU - Le, Nhu D.

AU - Levine, Douglas A.

AU - Massuger, Leon F.

AU - Matsuo, Keitaro

AU - May, Taymaa

AU - McNeish, Iain A.

AU - Menon, Usha

AU - Modugno, Francesmary

AU - Monteiro, Alvaro N.

AU - Moorman, Patricia G.

AU - Moysich, Kirsten B.

AU - Ness, Roberta B.

AU - Nevanlinna, Heli

AU - Olsson, Hakan

AU - Onland-Moret, N. Charlotte

AU - Park, Sue K.

AU - Paul, James

AU - Pearce, Celeste L.

AU - Pejovic, Tanja

AU - Phelan, Catherine M.

AU - Pike, Malcolm C.

AU - Ramus, Susan J.

AU - Riboli, Elio

AU - Rodriguez-Antona, Cristina

AU - Romieu, Isabelle

AU - Sandler, Dale P.

AU - Schildkraut, Joellen M.

AU - Setiawan, Veronica W.

AU - Shan, Kang

AU - Siddiqui, Nadeem

AU - Sieh, Weiva

AU - Stampfer, Meir J.

AU - Sutphen, Rebecca

AU - Swerdlow, Anthony J.

AU - Szafron, Lukasz M.

AU - Teo, Soo Hwang

AU - Tworoger, Shelley S.

AU - Tyrer, Jonathan P.

AU - Webb, Penelope M.

AU - Wentzensen, Nicolas

AU - White, Emily

AU - Willett, Walter C.

AU - Wolk, Alicja

AU - Woo, Yin Ling

AU - Wu, Anna H.

AU - Yan, Li

AU - Yannoukakos, Drakoulis

AU - Chenevix-Trench, Georgia

AU - Sellers, Thomas A.

AU - Pharoah, Paul D. P.

AU - Zheng, Wei

AU - Long, Jirong

PY - 2019/2/1

Y1 - 2019/2/1

KW - SUSCEPTIBILITY LOCI

KW - WIDE ASSOCIATION

KW - DISEASE

KW - MAPT

KW - PROTEIN

KW - TISSUE

KW - GWAS

KW - IDENTIFICATION

KW - VARIANTS

KW - THERAPY

KW - 3122 Cancers

U2 - 10.1158/0008-5472.CAN-18-2726

DO - 10.1158/0008-5472.CAN-18-2726

M3 - Article

VL - 79

SP - 505

EP - 517

JO - Cancer Research

JF - Cancer Research

SN - 0008-5472

IS - 3

ER -