Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

Kyle J. Gaulton, Teresa Ferreira, Yeji Lee, Anne Raimondo, Reedik Maegi, Michael E. Reschen, Anubha Mahajan, Adam Locke, N. William Rayner, Neil Robertson, Robert A. Scott, Inga Prokopenko, Laura J. Scott, Todd Green, Thomas Sparso, Dorothee Thuillier, Loic Yengo, Harald Grallert, Simone Wahl, Mattias FranbergRona J. Strawbridge, Hans Kestler, Himanshu Chheda, Lewin Eisele, Stefan Gustafsson, Valgerdur Steinthorsdottir, Gudmar Thorleifsson, Lu Qi, Lennart C. Karssen, Elisabeth M. van Leeuwen, Sara M. Willems, Man Li, Han Chen, Christian Fuchsberger, Phoenix Kwan, Clement Ma, Michael Linderman, Yingchang Lu, Soren K. Thomsen, Jana K. Rundle, Nicola L. Beer, Martijn van de Bunt, Anil Chalisey, Hyun Min Kang, Benjamin F. Voight, Goncalo R. Abecasis, Peter Almgren, Damiano Baldassarre, Beverley Balkau, Rafn Benediktsson, Matthias Blueher, Heiner Boeing, Lori L. Bonnycastle, Erwin P. Bottinger, Noel P. Burtt, Jason Carey, Guillaume Charpentier, Peter S. Chines, Marilyn C. Cornelis, David J. Couper, Andrew T. Crenshaw, Rob M. van Dam, Alex S. F. Doney, Mozhgan Dorkhan, Sarah Edkins, Johan G. Eriksson, Tonu Esko, Elodie Eury, Joao Fadista, Jason Flannick, Pierre Fontanillas, Caroline Fox, Paul W. Franks, Karl Gertow, Christian Gieger, Bruna Gigante, Omri Gottesman, George B. Grant, Niels Grarup, Christopher J. Groves, Maija Hassinen, Christian T. Have, Christian Herder, Oddgeir L. Holmen, Astradur B. Hreidarsson, Steve E. Humphries, David J. Hunter, Anne U. Jackson, Anna Jonsson, Marit E. Jorgensen, Torben Jorgensen, Wen-Hong L. Kao, Nicola D. Kerrison, Leena Kinnunen, Norman Klopp, Augustine Kong, Peter Kovacs, Peter Kraft, Jasmina Kravic, Cordelia Langford, Karin Leander, Liming Liang, Peter Lichtner, Cecilia M. Lindgren, Eero Lindholm, Allan Linneberg, Ching-Ti Liu, Stephane Lobbens, Jian'an Luan, Valeriya Lyssenko, Satu Mannisto, Olga McLeod, Julia Meyer, Evelin Mihailov, Ghazala Mirza, Thomas W. Muehleisen, Martina Mueller-Nurasyid, Carmen Navarro, Markus M. Noethen, Nikolay N. Oskolkov, Katharine R. Owen, Domenico Palli, Sonali Pechlivanis, Leena Peltonen, John R. B. Perry, Carl G. P. Platou, Michael Roden, Douglas Ruderfer, Denis Rybin, Yvonne T. van der Schouw, Bengt Sennblad, Gunnar Sigurdsson, Alena Stancakova, Gerald Steinbach, Petter Storm, Konstantin Strauch, Heather M. Stringham, Qi Sun, Barbara Thorand, Emmi Tikkanen, Anke Tonjes, Joseph Trakalo, Elena Tremoli, Tiinamaija Tuomi, Roman Wennauer, Steven Wiltshire, Andrew R. Wood, Eleftheria Zeggini, Ian Dunham, Ewan Birney, Lorenzo Pasquali, Jorge Ferrer, Ruth J. F. Loos, Josee Dupuis, Jose C. Florez, Eric Boerwinkle, James S. Pankow, Cornelia van Duijn, Eric Sijbrands, James B. Meigs, Frank B. Hu, Unnur Thorsteinsdottir, Kari Stefansson, Timo A. Lakka, Rainer Rauramaa, Michael Stumvoll, Nancy L. Pedersen, Lars Lind, Sirkka M. Keinanen-Kiukaanniemi, Eeva Korpi-Hyovalti, Timo E. Saaristo, Juha Saltevo, Johanna Kuusisto, Markku Laakso, Andres Metspalu, Raimund Erbel, Karl-Heinz Joecke, Susanne Moebus, Samuli Ripatti, Veikko Salomaa, Erik Ingelsson, Bernhard O. Boehm, Richard N. Bergman, Francis S. Collins, Karen L. Mohlke, Heikki Koistinen, Jaakko Tuomilehto, Kristian Hveem, Inger Njolstad, Panagiotis Deloukas, Peter J. Donnelly, Timothy M. Frayling, Andrew T. Hattersley, Ulf de Faire, Anders Hamsten, Thomas Illig, Annette Peters, Stephane Cauchi, Rob Sladek, Philippe Froguel, Torben Hansen, Oluf Pedersen, Andrew D. Morris, Collin N. A. Palmer, Sekar Kathiresan, Olle Melander, Peter M. Nilsson, Leif C. Groop, Ines Barroso, Claudia Langenberg, Nicholas J. Wareham, Christopher A. O'Callaghan, Anna L. Gloyn, David Altshuler, Michael Boehnke, Tanya M. Teslovich, Mark I. McCarthy, Andrew P. Morris, DIAbet Genetics Replication Meta-A

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalNature Genetics
Volume47
Issue number12
Pages (from-to)1415-1425
Number of pages14
ISSN1061-4036
DOIs
Publication statusPublished - Dec 2015
MoE publication typeA1 Journal article-refereed

Fields of Science

  • LARGE-SCALE ASSOCIATION
  • HUMAN PANCREATIC-ISLETS
  • WIDE ASSOCIATION
  • BETA-CELL
  • TRANSCRIPTION FACTORS
  • GLUCOSE-HOMEOSTASIS
  • GENOTYPE IMPUTATION
  • INSULIN-SECRETION
  • COMMON VARIANTS
  • GLYCEMIC TRAITS
  • 3121 General medicine, internal medicine and other clinical medicine
  • 3142 Public health care science, environmental and occupational health

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