Genetic Liability to Higher Muscle Strength Associates With a Lower Risk of Cardiovascular Disease Mortality in Men Irrespective of Leisure-Time Physical Activity in Adulthood: A Longitudinal Cohort Study

Päivi Herranen; Katja Waller; Laura Joensuu; Teemu Palviainen; Eija K. Laakkonen; Jaakko Kaprio; Elina Sillanpää

doi:10.1161/JAHA.124.036941

Genetic Liability to Higher Muscle Strength Associates With a Lower Risk of Cardiovascular Disease Mortality in Men Irrespective of Leisure-Time Physical Activity in Adulthood: A Longitudinal Cohort Study

Päivi Herranen
, Katja Waller
, Laura Joensuu
, Teemu Palviainen
, Eija K. Laakkonen
, Jaakko Kaprio
, Elina Sillanpää

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	e036941
Journal	Journal of the American Heart Association
Volume	14
Issue number	9
Number of pages	14
ISSN	2047-9980
DOIs	https://doi.org/10.1161/JAHA.124.036941
Publication status	Published - 6 May 2025
MoE publication type	A1 Journal article-refereed

Fields of Science

Cardiovascular mortality
Handgrip strength
Lifestyle
Polygenic score
3141 Health care science

Access to Document

10.1161/JAHA.124.036941Licence: CC BY-NC-ND

herranen-et-al-genetic-liability-to-higher-muscle-strength-associates-with-a-lower-risk-of-cardiovascular-diseaseFinal published version, 464 KBLicence: CC BY-NC-ND

Cite this

Herranen, P., Waller, K., Joensuu, L., Palviainen, T., Laakkonen, E. K., Kaprio, J., & Sillanpää, E. (2025). Genetic Liability to Higher Muscle Strength Associates With a Lower Risk of Cardiovascular Disease Mortality in Men Irrespective of Leisure-Time Physical Activity in Adulthood: A Longitudinal Cohort Study. Journal of the American Heart Association, 14(9), Article e036941. https://doi.org/10.1161/JAHA.124.036941

@article{0a9dc60f0c62459383424440b99c16d6,

title = "Genetic Liability to Higher Muscle Strength Associates With a Lower Risk of Cardiovascular Disease Mortality in Men Irrespective of Leisure-Time Physical Activity in Adulthood: A Longitudinal Cohort Study",

keywords = "Cardiovascular mortality, Handgrip strength, Lifestyle, Polygenic score, 3141 Health care science",

author = "P{\"a}ivi Herranen and Katja Waller and Laura Joensuu and Teemu Palviainen and Laakkonen, \{Eija K.\} and Jaakko Kaprio and Elina Sillanp{\"a}{\"a}",

year = "2025",

month = may,

day = "6",

doi = "10.1161/JAHA.124.036941",

language = "English",

volume = "14",

journal = "Journal of the American Heart Association",

issn = "2047-9980",

publisher = "American Heart Association Inc.",

number = "9",

}

Herranen, P, Waller, K, Joensuu, L, Palviainen, T, Laakkonen, EK, Kaprio, J & Sillanpää, E 2025, 'Genetic Liability to Higher Muscle Strength Associates With a Lower Risk of Cardiovascular Disease Mortality in Men Irrespective of Leisure-Time Physical Activity in Adulthood: A Longitudinal Cohort Study', Journal of the American Heart Association, vol. 14, no. 9, e036941. https://doi.org/10.1161/JAHA.124.036941

Genetic Liability to Higher Muscle Strength Associates With a Lower Risk of Cardiovascular Disease Mortality in Men Irrespective of Leisure-Time Physical Activity in Adulthood: A Longitudinal Cohort Study. / Herranen, Päivi; Waller, Katja; Joensuu, Laura et al.
In: Journal of the American Heart Association, Vol. 14, No. 9, e036941, 06.05.2025.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - Genetic Liability to Higher Muscle Strength Associates With a Lower Risk of Cardiovascular Disease Mortality in Men Irrespective of Leisure-Time Physical Activity in Adulthood

T2 - A Longitudinal Cohort Study

AU - Herranen, Päivi

AU - Waller, Katja

AU - Joensuu, Laura

AU - Palviainen, Teemu

AU - Laakkonen, Eija K.

AU - Kaprio, Jaakko

AU - Sillanpää, Elina

PY - 2025/5/6

Y1 - 2025/5/6

KW - Cardiovascular mortality

KW - Handgrip strength

KW - Lifestyle

KW - Polygenic score

KW - 3141 Health care science

U2 - 10.1161/JAHA.124.036941

DO - 10.1161/JAHA.124.036941

M3 - Article

C2 - 40240949

SN - 2047-9980

VL - 14

JO - Journal of the American Heart Association

JF - Journal of the American Heart Association

IS - 9

M1 - e036941

ER -

Herranen P, Waller K, Joensuu L, Palviainen T, Laakkonen EK, Kaprio J et al. Genetic Liability to Higher Muscle Strength Associates With a Lower Risk of Cardiovascular Disease Mortality in Men Irrespective of Leisure-Time Physical Activity in Adulthood: A Longitudinal Cohort Study. Journal of the American Heart Association. 2025 May 6;14(9):e036941. doi: 10.1161/JAHA.124.036941