Genetic recombination pathways and their application for genome modification of human embryonic stem cells

Mikko Nieminen, Timo Tuuri, Harri Savilahti

Research output: Contribution to journalReview ArticleScientificpeer-review

Original languageEnglish
JournalExperimental Cell Research
Volume316
Issue number16
Pages (from-to)2578-2586
Number of pages9
ISSN0014-4827
DOIs
Publication statusPublished - 2010
MoE publication typeA2 Review article in a scientific journal

Fields of Science

  • Human embryonic stem cells
  • Pluripotent
  • iPS cells
  • Gene targeting
  • Homologous recombination
  • HR
  • Non-homologous end joining
  • NHEJ
  • Site-specific recombination
  • DNA transposition
  • ZINC-FINGER NUCLEASES
  • STABLE TRANSGENE EXPRESSION
  • SITE-SPECIFIC RECOMBINATION
  • HOMOLOGOUS RECOMBINATION
  • HUMAN ESCS
  • TARGETING VECTORS
  • HUMAN FIBROBLASTS
  • EFFICIENT
  • INTEGRATION
  • LOCUS
  • 311 Basic medicine

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