Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

Tuomas O. Kilpelainen, M. Carola Zillikens, Alena Stancakova, Francis M. Finucane, Janina S. Ried, Claudia Langenberg, Weihua Zhang, Jacques S. Beckmann, Jian'an Luan, Liesbeth Vandenput, Unnur Styrkarsdottir, Yanhua Zhou, Albert Vernon Smith, Jing-Hua Zhao, Najaf Amin, Sailaja Vedantam, So-Youn Shin, Talin Haritunians, Mao Fu, Mary F. FeitosaMeena Kumari, Bjarni V. Halldorsson, Emmi Tikkanen, Massimo Mangino, Caroline Hayward, Ci Song, Alice M. Arnold, Yurii S. Aulchenko, Ben A. Oostra, Harry Campbell, L. Adrienne Cupples, Kathryn E. Davis, Angela Doering, Gudny Eiriksdottir, Karol Estrada, Jose Manuel Fernandez-Real, Melissa Garcia, Christian Gieger, Nicole L. Glazer, Candace Guiducci, Albert Hofman, Steve E. Humphries, Bo Isomaa, Leonie C. Jacobs, Antti Jula, David Karasik, Magnus K. Karlsson, Kay-Tee Khaw, Lauren J. Kim, Mika Kivimaeki, Norman Klopp, Brigitte Kuehnel, Johanna Kuusisto, Yongmei Liu, Osten Ljunggren, Mattias Lorentzon, Robert N. Luben, Barbara McKnight, Dan Mellstrom, Braxton D. Mitchell, Vincent Mooser, Jose Maria Moreno, Satu Mannisto, Jeffery R. O'Connell, Laura Pascoe, Leena Palotie, Belen Peral, Markus Perola, Bruce M. Psaty, Veikko Salomaa, David B. Savage, Robert K. Semple, Tatjana Skaric-Juric, Gunnar Sigurdsson, Kijoung S. Song, Timothy D. Spector, Ann-Christine Syvanen, Philippa J. Talmud, Gudmar Thorleifsson, Unnur Thorsteinsdottir, Andre G. Uitterlinden, Cornelia M. van Duijn, Antonio Vidal-Puig, Sarah H. Wild, Alan F. Wright, Deborah J. Clegg, Eric Schadt, James F. Wilson, Igor Rudan, Samuli Ripatti, Ingrid B. Borecki, Alan R. Shuldiner, Erik Ingelsson, John-Olov Jansson, Robert C. Kaplan, Vilmundur Gudnason, Tamara B. Harris, Leif Groop, Douglas P. Kiel, Fernando Rivadeneira, Mark Walker, Ines Barroso, Peter Vollenweider, Gerard Waeber, John C. Chambers, Jaspal S. Kooner, Nicole Soranzo, Joel N. Hirschhorn, Kari Stefansson, H-Erich Wichmann, Claes Ohlsson, Stephen O'Rahilly, Nicholas J. Wareham, Elizabeth K. Speliotes, Caroline S. Fox, Markku Laakso, Ruth J. F. Loos

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalNature Genetics
Volume43
Issue number8
Pages (from-to)753-U58
Number of pages11
ISSN1061-4036
DOIs
Publication statusPublished - 2011
MoE publication typeA1 Journal article-refereed

Fields of Science

  • GENOME-WIDE ASSOCIATION
  • INSULIN-RECEPTOR SUBSTRATE-1
  • BODY-MASS INDEX
  • ADIPOCYTE DIFFERENTIATION
  • ADULT OBESITY
  • FTO GENE
  • LOCI
  • RESISTANCE
  • EXPRESSION
  • MIGRATION
  • 3111 Biomedicine

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