Genome-scale screens identify factors regulating tumor cell responses to natural killer cells

Michal Sheffer; Emily Lowry; Nicky Beelen; Minasri Borah; Suha Naffar-Abu Amara; Chris C. Mader; Jennifer A. Roth; Aviad Tsherniak; Samuel S. Freeman; Olga Dashevsky; Sara Gandolfi; Samantha Bender; Jordan G. Bryan; Cong Zhu; Li Wang; Ifrah Tariq; Govinda M. Kamath; Ricardo De Matos Simoes; Eugen Dhimolea; Channing Yu; Yiguo Hu; Olli Dufva; Marios Giannakis; Vasilis Syrgkanis; Ernest Fraenkel; Todd Golub; Rizwan Romee; Satu Mustjoki; Aedin C. Culhane; Lotte Wieten; Constantine S. Mitsiades

doi:10.1038/s41588-021-00889-w

Genome-scale screens identify factors regulating tumor cell responses to natural killer cells

Michal Sheffer, Emily Lowry, Nicky Beelen, Minasri Borah, Suha Naffar-Abu Amara, Chris C. Mader, Jennifer A. Roth, Aviad Tsherniak, Samuel S. Freeman, Olga Dashevsky, Sara Gandolfi, Samantha Bender, Jordan G. Bryan, Cong Zhu, Li Wang, Ifrah Tariq, Govinda M. Kamath, Ricardo De Matos Simoes, Eugen Dhimolea, Channing YuYiguo Hu, Olli Dufva, Marios Giannakis, Vasilis Syrgkanis, Ernest Fraenkel, Todd Golub, Rizwan Romee, Satu Mustjoki, Aedin C. Culhane, Lotte Wieten, Constantine S. Mitsiades

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Nature Genetics
Volume	53
Issue number	8
Pages (from-to)	1196–1206
Number of pages	21
ISSN	1061-4036
DOIs	https://doi.org/10.1038/s41588-021-00889-w
Publication status	Published - Aug 2021
MoE publication type	A1 Journal article-refereed

Fields of Science

T-CELLS
MELANOMA
GAMMA
PEMBROLIZUMAB
INHIBITION
RESISTANCE
EXPANSION
SARCOMA
SARC028
LIGAND
3122 Cancers
1184 Genetics, developmental biology, physiology

Access to Document

10.1038/s41588-021-00889-w

Cite this

Sheffer, M., Lowry, E., Beelen, N., Borah, M., Naffar-Abu Amara, S., Mader, C. C., Roth, J. A., Tsherniak, A., Freeman, S. S., Dashevsky, O., Gandolfi, S., Bender, S., Bryan, J. G., Zhu, C., Wang, L., Tariq, I., Kamath, G. M., Simoes, R. D. M., Dhimolea, E., ... Mitsiades, C. S. (2021). Genome-scale screens identify factors regulating tumor cell responses to natural killer cells. Nature Genetics, 53(8), 1196–1206. https://doi.org/10.1038/s41588-021-00889-w

@article{00cddc22340640819d4d2dc86c3cad13,

title = "Genome-scale screens identify factors regulating tumor cell responses to natural killer cells",

keywords = "T-CELLS, MELANOMA, GAMMA, PEMBROLIZUMAB, INHIBITION, RESISTANCE, EXPANSION, SARCOMA, SARC028, LIGAND, 3122 Cancers, 1184 Genetics, developmental biology, physiology",

author = "Michal Sheffer and Emily Lowry and Nicky Beelen and Minasri Borah and {Naffar-Abu Amara}, Suha and Mader, {Chris C.} and Roth, {Jennifer A.} and Aviad Tsherniak and Freeman, {Samuel S.} and Olga Dashevsky and Sara Gandolfi and Samantha Bender and Bryan, {Jordan G.} and Cong Zhu and Li Wang and Ifrah Tariq and Kamath, {Govinda M.} and Simoes, {Ricardo De Matos} and Eugen Dhimolea and Channing Yu and Yiguo Hu and Olli Dufva and Marios Giannakis and Vasilis Syrgkanis and Ernest Fraenkel and Todd Golub and Rizwan Romee and Satu Mustjoki and Culhane, {Aedin C.} and Lotte Wieten and Mitsiades, {Constantine S.}",

year = "2021",

month = aug,

doi = "10.1038/s41588-021-00889-w",

language = "English",

volume = "53",

pages = "1196–1206",

journal = "Nature Genetics",

issn = "1061-4036",

publisher = "Nature Research ",

number = "8",

}

Sheffer, M, Lowry, E, Beelen, N, Borah, M, Naffar-Abu Amara, S, Mader, CC, Roth, JA, Tsherniak, A, Freeman, SS, Dashevsky, O, Gandolfi, S, Bender, S, Bryan, JG, Zhu, C, Wang, L, Tariq, I, Kamath, GM, Simoes, RDM, Dhimolea, E, Yu, C, Hu, Y, Dufva, O, Giannakis, M, Syrgkanis, V, Fraenkel, E, Golub, T, Romee, R, Mustjoki, S, Culhane, AC, Wieten, L & Mitsiades, CS 2021, 'Genome-scale screens identify factors regulating tumor cell responses to natural killer cells', Nature Genetics, vol. 53, no. 8, pp. 1196–1206. https://doi.org/10.1038/s41588-021-00889-w

TY - JOUR

T1 - Genome-scale screens identify factors regulating tumor cell responses to natural killer cells

AU - Sheffer, Michal

AU - Lowry, Emily

AU - Beelen, Nicky

AU - Borah, Minasri

AU - Naffar-Abu Amara, Suha

AU - Mader, Chris C.

AU - Roth, Jennifer A.

AU - Tsherniak, Aviad

AU - Freeman, Samuel S.

AU - Dashevsky, Olga

AU - Gandolfi, Sara

AU - Bender, Samantha

AU - Bryan, Jordan G.

AU - Zhu, Cong

AU - Wang, Li

AU - Tariq, Ifrah

AU - Kamath, Govinda M.

AU - Simoes, Ricardo De Matos

AU - Dhimolea, Eugen

AU - Yu, Channing

AU - Hu, Yiguo

AU - Dufva, Olli

AU - Giannakis, Marios

AU - Syrgkanis, Vasilis

AU - Fraenkel, Ernest

AU - Golub, Todd

AU - Romee, Rizwan

AU - Mustjoki, Satu

AU - Culhane, Aedin C.

AU - Wieten, Lotte

AU - Mitsiades, Constantine S.

PY - 2021/8

Y1 - 2021/8

KW - T-CELLS

KW - MELANOMA

KW - GAMMA

KW - PEMBROLIZUMAB

KW - INHIBITION

KW - RESISTANCE

KW - EXPANSION

KW - SARCOMA

KW - SARC028

KW - LIGAND

KW - 3122 Cancers

KW - 1184 Genetics, developmental biology, physiology

U2 - 10.1038/s41588-021-00889-w

DO - 10.1038/s41588-021-00889-w

M3 - Article

SN - 1061-4036

VL - 53

SP - 1196

EP - 1206

JO - Nature Genetics

JF - Nature Genetics

IS - 8

ER -