Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to Hydrochlorothiazide

Erika Salvi; Zhiying Wang; Federica Rizzi; Yan Gong; Caitrin W. McDonough; Sandosh Padmanabhan; Timo P. Hiltunen; Chiara Lanzani; Roberta Zaninello; Martina Chittani; Kent R. Bailey; Antti-Pekka Sarin; Matteo Barcella; Olle Melander; Arlene B. Chapman; Paolo Manunta; Kimmo K. Kontula; Nicola Glorioso; Daniele Cusi; Anna F. Dominiczak; Julie A. Johnson; Cristina Barlassina; Eric Boerwinkle; Rhonda M. Cooper-DeHoff; Stephen T. Turner

doi:10.1161/HYPERTENSIONAHA.116.08267

Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to Hydrochlorothiazide

Erika Salvi, Zhiying Wang, Federica Rizzi, Yan Gong, Caitrin W. McDonough, Sandosh Padmanabhan, Timo P. Hiltunen, Chiara Lanzani, Roberta Zaninello, Martina Chittani, Kent R. Bailey, Antti-Pekka Sarin, Matteo Barcella, Olle Melander, Arlene B. Chapman, Paolo Manunta, Kimmo K. Kontula, Nicola Glorioso, Daniele Cusi, Anna F. DominiczakJulie A. Johnson, Cristina Barlassina, Eric Boerwinkle, Rhonda M. Cooper-DeHoff, Stephen T. Turner

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Hypertension
Volume	69
Issue number	1
Pages (from-to)	51-59
Number of pages	9
ISSN	0194-911X
DOIs	https://doi.org/10.1161/HYPERTENSIONAHA.116.08267
Publication status	Published - Jan 2017
MoE publication type	A1 Journal article-refereed

Fields of Science

blood pressure response
diuretics
genome-wide association study
hydrochlorothiazide
hypertension
meta-analysis
pharmacogenomics
INFLUENCING ANTIHYPERTENSIVE RESPONSE
LEFT-VENTRICULAR STRUCTURE
OUABAIN-LIKE COMPOUND
ESSENTIAL-HYPERTENSION
ENDOGENOUS OUABAIN
STEROID-BIOSYNTHESIS
ASSOCIATION ANALYSIS
THIAZIDE DIURETICS
COMPLEX TRAITS
MOUSE KIDNEY
3121 General medicine, internal medicine and other clinical medicine

Access to Document

10.1161/HYPERTENSIONAHA.116.08267

Cite this

Salvi, E., Wang, Z., Rizzi, F., Gong, Y., McDonough, C. W., Padmanabhan, S., Hiltunen, T. P., Lanzani, C., Zaninello, R., Chittani, M., Bailey, K. R., Sarin, A.-P., Barcella, M., Melander, O., Chapman, A. B., Manunta, P., Kontula, K. K., Glorioso, N., Cusi, D., ... Turner, S. T. (2017). Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to Hydrochlorothiazide. Hypertension, 69(1), 51-59. https://doi.org/10.1161/HYPERTENSIONAHA.116.08267

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title = "Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to Hydrochlorothiazide",

keywords = "blood pressure response, diuretics, genome-wide association study, hydrochlorothiazide, hypertension, meta-analysis, pharmacogenomics, INFLUENCING ANTIHYPERTENSIVE RESPONSE, LEFT-VENTRICULAR STRUCTURE, OUABAIN-LIKE COMPOUND, ESSENTIAL-HYPERTENSION, ENDOGENOUS OUABAIN, STEROID-BIOSYNTHESIS, ASSOCIATION ANALYSIS, THIAZIDE DIURETICS, COMPLEX TRAITS, MOUSE KIDNEY, 3121 General medicine, internal medicine and other clinical medicine",

author = "Erika Salvi and Zhiying Wang and Federica Rizzi and Yan Gong and McDonough, {Caitrin W.} and Sandosh Padmanabhan and Hiltunen, {Timo P.} and Chiara Lanzani and Roberta Zaninello and Martina Chittani and Bailey, {Kent R.} and Antti-Pekka Sarin and Matteo Barcella and Olle Melander and Chapman, {Arlene B.} and Paolo Manunta and Kontula, {Kimmo K.} and Nicola Glorioso and Daniele Cusi and Dominiczak, {Anna F.} and Johnson, {Julie A.} and Cristina Barlassina and Eric Boerwinkle and Cooper-DeHoff, {Rhonda M.} and Turner, {Stephen T.}",

year = "2017",

month = jan,

doi = "10.1161/HYPERTENSIONAHA.116.08267",

language = "English",

volume = "69",

pages = "51--59",

journal = "Hypertension",

issn = "0194-911X",

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Salvi, E, Wang, Z, Rizzi, F, Gong, Y, McDonough, CW, Padmanabhan, S, Hiltunen, TP, Lanzani, C, Zaninello, R, Chittani, M, Bailey, KR, Sarin, A-P, Barcella, M, Melander, O, Chapman, AB, Manunta, P, Kontula, KK, Glorioso, N, Cusi, D, Dominiczak, AF, Johnson, JA, Barlassina, C, Boerwinkle, E, Cooper-DeHoff, RM & Turner, ST 2017, 'Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to Hydrochlorothiazide', Hypertension, vol. 69, no. 1, pp. 51-59. https://doi.org/10.1161/HYPERTENSIONAHA.116.08267

TY - JOUR

T1 - Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to Hydrochlorothiazide

AU - Salvi, Erika

AU - Wang, Zhiying

AU - Rizzi, Federica

AU - Gong, Yan

AU - McDonough, Caitrin W.

AU - Padmanabhan, Sandosh

AU - Hiltunen, Timo P.

AU - Lanzani, Chiara

AU - Zaninello, Roberta

AU - Chittani, Martina

AU - Bailey, Kent R.

AU - Sarin, Antti-Pekka

AU - Barcella, Matteo

AU - Melander, Olle

AU - Chapman, Arlene B.

AU - Manunta, Paolo

AU - Kontula, Kimmo K.

AU - Glorioso, Nicola

AU - Cusi, Daniele

AU - Dominiczak, Anna F.

AU - Johnson, Julie A.

AU - Barlassina, Cristina

AU - Boerwinkle, Eric

AU - Cooper-DeHoff, Rhonda M.

AU - Turner, Stephen T.

PY - 2017/1

Y1 - 2017/1

KW - blood pressure response

KW - diuretics

KW - genome-wide association study

KW - hydrochlorothiazide

KW - hypertension

KW - meta-analysis

KW - pharmacogenomics

KW - INFLUENCING ANTIHYPERTENSIVE RESPONSE

KW - LEFT-VENTRICULAR STRUCTURE

KW - OUABAIN-LIKE COMPOUND

KW - ESSENTIAL-HYPERTENSION

KW - ENDOGENOUS OUABAIN

KW - STEROID-BIOSYNTHESIS

KW - ASSOCIATION ANALYSIS

KW - THIAZIDE DIURETICS

KW - COMPLEX TRAITS

KW - MOUSE KIDNEY

KW - 3121 General medicine, internal medicine and other clinical medicine

U2 - 10.1161/HYPERTENSIONAHA.116.08267

DO - 10.1161/HYPERTENSIONAHA.116.08267

M3 - Article

SN - 0194-911X

VL - 69

SP - 51

EP - 59

JO - Hypertension

JF - Hypertension

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