Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to Hydrochlorothiazide

Erika Salvi, Zhiying Wang, Federica Rizzi, Yan Gong, Caitrin W. McDonough, Sandosh Padmanabhan, Timo P. Hiltunen, Chiara Lanzani, Roberta Zaninello, Martina Chittani, Kent R. Bailey, Antti-Pekka Sarin, Matteo Barcella, Olle Melander, Arlene B. Chapman, Paolo Manunta, Kimmo K. Kontula, Nicola Glorioso, Daniele Cusi, Anna F. Dominiczak & 5 others Julie A. Johnson, Cristina Barlassina, Eric Boerwinkle, Rhonda M. Cooper-DeHoff, Stephen T. Turner

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalHypertension
Volume69
Issue number1
Pages (from-to)51-59
Number of pages9
ISSN0194-911X
DOIs
Publication statusPublished - Jan 2017
MoE publication typeA1 Journal article-refereed

Fields of Science

  • blood pressure response
  • diuretics
  • genome-wide association study
  • hydrochlorothiazide
  • hypertension
  • meta-analysis
  • pharmacogenomics
  • INFLUENCING ANTIHYPERTENSIVE RESPONSE
  • LEFT-VENTRICULAR STRUCTURE
  • OUABAIN-LIKE COMPOUND
  • ESSENTIAL-HYPERTENSION
  • ENDOGENOUS OUABAIN
  • STEROID-BIOSYNTHESIS
  • ASSOCIATION ANALYSIS
  • THIAZIDE DIURETICS
  • COMPLEX TRAITS
  • MOUSE KIDNEY
  • 3121 Internal medicine

Cite this

Salvi, E., Wang, Z., Rizzi, F., Gong, Y., McDonough, C. W., Padmanabhan, S., ... Turner, S. T. (2017). Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to Hydrochlorothiazide. Hypertension, 69(1), 51-59. https://doi.org/10.1161/HYPERTENSIONAHA.116.08267
Salvi, Erika ; Wang, Zhiying ; Rizzi, Federica ; Gong, Yan ; McDonough, Caitrin W. ; Padmanabhan, Sandosh ; Hiltunen, Timo P. ; Lanzani, Chiara ; Zaninello, Roberta ; Chittani, Martina ; Bailey, Kent R. ; Sarin, Antti-Pekka ; Barcella, Matteo ; Melander, Olle ; Chapman, Arlene B. ; Manunta, Paolo ; Kontula, Kimmo K. ; Glorioso, Nicola ; Cusi, Daniele ; Dominiczak, Anna F. ; Johnson, Julie A. ; Barlassina, Cristina ; Boerwinkle, Eric ; Cooper-DeHoff, Rhonda M. ; Turner, Stephen T. / Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to Hydrochlorothiazide. In: Hypertension. 2017 ; Vol. 69, No. 1. pp. 51-59.
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title = "Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to Hydrochlorothiazide",
keywords = "blood pressure response, diuretics, genome-wide association study, hydrochlorothiazide, hypertension, meta-analysis, pharmacogenomics, INFLUENCING ANTIHYPERTENSIVE RESPONSE, LEFT-VENTRICULAR STRUCTURE, OUABAIN-LIKE COMPOUND, ESSENTIAL-HYPERTENSION, ENDOGENOUS OUABAIN, STEROID-BIOSYNTHESIS, ASSOCIATION ANALYSIS, THIAZIDE DIURETICS, COMPLEX TRAITS, MOUSE KIDNEY, 3121 Internal medicine",
author = "Erika Salvi and Zhiying Wang and Federica Rizzi and Yan Gong and McDonough, {Caitrin W.} and Sandosh Padmanabhan and Hiltunen, {Timo P.} and Chiara Lanzani and Roberta Zaninello and Martina Chittani and Bailey, {Kent R.} and Antti-Pekka Sarin and Matteo Barcella and Olle Melander and Chapman, {Arlene B.} and Paolo Manunta and Kontula, {Kimmo K.} and Nicola Glorioso and Daniele Cusi and Dominiczak, {Anna F.} and Johnson, {Julie A.} and Cristina Barlassina and Eric Boerwinkle and Cooper-DeHoff, {Rhonda M.} and Turner, {Stephen T.}",
year = "2017",
month = "1",
doi = "10.1161/HYPERTENSIONAHA.116.08267",
language = "English",
volume = "69",
pages = "51--59",
journal = "Hypertension",
issn = "0194-911X",
publisher = "Lippincott williams & wilkins",
number = "1",

}

Salvi, E, Wang, Z, Rizzi, F, Gong, Y, McDonough, CW, Padmanabhan, S, Hiltunen, TP, Lanzani, C, Zaninello, R, Chittani, M, Bailey, KR, Sarin, A-P, Barcella, M, Melander, O, Chapman, AB, Manunta, P, Kontula, KK, Glorioso, N, Cusi, D, Dominiczak, AF, Johnson, JA, Barlassina, C, Boerwinkle, E, Cooper-DeHoff, RM & Turner, ST 2017, 'Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to Hydrochlorothiazide', Hypertension, vol. 69, no. 1, pp. 51-59. https://doi.org/10.1161/HYPERTENSIONAHA.116.08267

Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to Hydrochlorothiazide. / Salvi, Erika; Wang, Zhiying; Rizzi, Federica; Gong, Yan; McDonough, Caitrin W.; Padmanabhan, Sandosh; Hiltunen, Timo P.; Lanzani, Chiara; Zaninello, Roberta; Chittani, Martina; Bailey, Kent R.; Sarin, Antti-Pekka; Barcella, Matteo; Melander, Olle; Chapman, Arlene B.; Manunta, Paolo; Kontula, Kimmo K.; Glorioso, Nicola; Cusi, Daniele; Dominiczak, Anna F.; Johnson, Julie A.; Barlassina, Cristina; Boerwinkle, Eric; Cooper-DeHoff, Rhonda M.; Turner, Stephen T.

In: Hypertension, Vol. 69, No. 1, 01.2017, p. 51-59.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to Hydrochlorothiazide

AU - Salvi, Erika

AU - Wang, Zhiying

AU - Rizzi, Federica

AU - Gong, Yan

AU - McDonough, Caitrin W.

AU - Padmanabhan, Sandosh

AU - Hiltunen, Timo P.

AU - Lanzani, Chiara

AU - Zaninello, Roberta

AU - Chittani, Martina

AU - Bailey, Kent R.

AU - Sarin, Antti-Pekka

AU - Barcella, Matteo

AU - Melander, Olle

AU - Chapman, Arlene B.

AU - Manunta, Paolo

AU - Kontula, Kimmo K.

AU - Glorioso, Nicola

AU - Cusi, Daniele

AU - Dominiczak, Anna F.

AU - Johnson, Julie A.

AU - Barlassina, Cristina

AU - Boerwinkle, Eric

AU - Cooper-DeHoff, Rhonda M.

AU - Turner, Stephen T.

PY - 2017/1

Y1 - 2017/1

KW - blood pressure response

KW - diuretics

KW - genome-wide association study

KW - hydrochlorothiazide

KW - hypertension

KW - meta-analysis

KW - pharmacogenomics

KW - INFLUENCING ANTIHYPERTENSIVE RESPONSE

KW - LEFT-VENTRICULAR STRUCTURE

KW - OUABAIN-LIKE COMPOUND

KW - ESSENTIAL-HYPERTENSION

KW - ENDOGENOUS OUABAIN

KW - STEROID-BIOSYNTHESIS

KW - ASSOCIATION ANALYSIS

KW - THIAZIDE DIURETICS

KW - COMPLEX TRAITS

KW - MOUSE KIDNEY

KW - 3121 Internal medicine

U2 - 10.1161/HYPERTENSIONAHA.116.08267

DO - 10.1161/HYPERTENSIONAHA.116.08267

M3 - Article

VL - 69

SP - 51

EP - 59

JO - Hypertension

JF - Hypertension

SN - 0194-911X

IS - 1

ER -