Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes

A. Xue; Y. Wu; Z. Zhu; F. Zhang; K.E. Kemper; Z. Zheng; L. Yengo; L.R. Lloyd-Jones; J. Sidorenko; M. Agbessi; H. Ahsan; I. Alves; A. Andiappan; P. Awadalla; A. Battle; F. Beutner; M.J. Bonder; D. Boomsma; M. Christiansen; A. Claringbould; P. Deelen; T. Esko; M.-J. Favé; L. Franke; T. Frayling; S. Gharib; G. Gibson; G. Hemani; R. Jansen; M. Kähönen; A. Kalnapenkis; S. Kasela; J. Kettunen; Y. Kim; H. Kirsten; P. Kovacs; K. Krohn; J. Kronberg-Guzman; V. Kukushkina; Z. Kutalik; B. Lee; T. Lehtimäki; M. Loeffler; U.M. Marigorta; A. Metspalu; L. Milani; M. Müller-Nurasyid; M. Nauck; M. Nivard; B. Penninx; M. Perola; N. Pervjakova; B. Pierce; J. Powell; H. Prokisch; B. Psaty; O. Raitakari; S. Ring; S. Ripatti; O. Rotzschke; S. Ruëger; A. Saha; M. Scholz; K. Schramm; I. Seppälä; M. Stumvoll; P. Sullivan; A. Teumer; J. Thiery; L. Tong; A. Tönjes; J. van Dongen; J. van Meurs; J. Verlouw; U. Völker; U. Võsa; H. Yaghootkar; B. Zeng; A.F. McRae; P.M. Visscher; J. Zeng; J. Yang

doi:10.1038/s41467-018-04951-w

Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes

A. Xue, Y. Wu, Z. Zhu, F. Zhang, K.E. Kemper, Z. Zheng, L. Yengo, L.R. Lloyd-Jones, J. Sidorenko, M. Agbessi, H. Ahsan, I. Alves, A. Andiappan, P. Awadalla, A. Battle, F. Beutner, M.J. Bonder, D. Boomsma, M. Christiansen, A. ClaringbouldP. Deelen, T. Esko, M.-J. Favé, L. Franke, T. Frayling, S. Gharib, G. Gibson, G. Hemani, R. Jansen, M. Kähönen, A. Kalnapenkis, S. Kasela, J. Kettunen, Y. Kim, H. Kirsten, P. Kovacs, K. Krohn, J. Kronberg-Guzman, V. Kukushkina, Z. Kutalik, B. Lee, T. Lehtimäki, M. Loeffler, U.M. Marigorta, A. Metspalu, L. Milani, M. Müller-Nurasyid, M. Nauck, M. Nivard, B. Penninx, M. Perola, N. Pervjakova, B. Pierce, J. Powell, H. Prokisch, B. Psaty, O. Raitakari, S. Ring, S. Ripatti, O. Rotzschke, S. Ruëger, A. Saha, M. Scholz, K. Schramm, I. Seppälä, M. Stumvoll, P. Sullivan, A. Teumer, J. Thiery, L. Tong, A. Tönjes, J. van Dongen, J. van Meurs, J. Verlouw, U. Völker, U. Võsa, H. Yaghootkar, B. Zeng, A.F. McRae, P.M. Visscher, J. Zeng, J. Yang

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	2941
Journal	Nature Communications
Volume	9
Issue number	1
Number of pages	14
ISSN	2041-1723
DOIs	https://doi.org/10.1038/s41467-018-04951-w
Publication status	Published - 2018
MoE publication type	A1 Journal article-refereed

Fields of Science

3111 Biomedicine
3121 General medicine, internal medicine and other clinical medicine

Access to Document

10.1038/s41467-018-04951-w

s41467-018-04951-w-1Final published version, 3.54 MBLicence: CC BY

Cite this

Xue, A., Wu, Y., Zhu, Z., Zhang, F., Kemper, K. E., Zheng, Z., Yengo, L., Lloyd-Jones, L. R., Sidorenko, J., Agbessi, M., Ahsan, H., Alves, I., Andiappan, A., Awadalla, P., Battle, A., Beutner, F., Bonder, M. J., Boomsma, D., Christiansen, M., ... Yang, J. (2018). Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes. Nature Communications, 9(1), [2941]. https://doi.org/10.1038/s41467-018-04951-w

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title = "Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes",

keywords = "3111 Biomedicine, 3121 General medicine, internal medicine and other clinical medicine",

author = "A. Xue and Y. Wu and Z. Zhu and F. Zhang and K.E. Kemper and Z. Zheng and L. Yengo and L.R. Lloyd-Jones and J. Sidorenko and M. Agbessi and H. Ahsan and I. Alves and A. Andiappan and P. Awadalla and A. Battle and F. Beutner and M.J. Bonder and D. Boomsma and M. Christiansen and A. Claringbould and P. Deelen and T. Esko and M.-J. Fav{\'e} and L. Franke and T. Frayling and S. Gharib and G. Gibson and G. Hemani and R. Jansen and M. K{\"a}h{\"o}nen and A. Kalnapenkis and S. Kasela and J. Kettunen and Y. Kim and H. Kirsten and P. Kovacs and K. Krohn and J. Kronberg-Guzman and V. Kukushkina and Z. Kutalik and B. Lee and T. Lehtim{\"a}ki and M. Loeffler and U.M. Marigorta and A. Metspalu and L. Milani and M. M{\"u}ller-Nurasyid and M. Nauck and M. Nivard and B. Penninx and M. Perola and N. Pervjakova and B. Pierce and J. Powell and H. Prokisch and B. Psaty and O. Raitakari and S. Ring and S. Ripatti and O. Rotzschke and S. Ru{\"e}ger and A. Saha and M. Scholz and K. Schramm and I. Sepp{\"a}l{\"a} and M. Stumvoll and P. Sullivan and A. Teumer and J. Thiery and L. Tong and A. T{\"o}njes and {van Dongen}, J. and {van Meurs}, J. and J. Verlouw and U. V{\"o}lker and U. V{\~o}sa and H. Yaghootkar and B. Zeng and A.F. McRae and P.M. Visscher and J. Zeng and J. Yang",

year = "2018",

doi = "10.1038/s41467-018-04951-w",

language = "English",

volume = "9",

journal = "Nature Communications",

issn = "2041-1723",

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Xue, A, Wu, Y, Zhu, Z, Zhang, F, Kemper, KE, Zheng, Z, Yengo, L, Lloyd-Jones, LR, Sidorenko, J, Agbessi, M, Ahsan, H, Alves, I, Andiappan, A, Awadalla, P, Battle, A, Beutner, F, Bonder, MJ, Boomsma, D, Christiansen, M, Claringbould, A, Deelen, P, Esko, T, Favé, M-J, Franke, L, Frayling, T, Gharib, S, Gibson, G, Hemani, G, Jansen, R, Kähönen, M, Kalnapenkis, A, Kasela, S, Kettunen, J, Kim, Y, Kirsten, H, Kovacs, P, Krohn, K, Kronberg-Guzman, J, Kukushkina, V, Kutalik, Z, Lee, B, Lehtimäki, T, Loeffler, M, Marigorta, UM, Metspalu, A, Milani, L, Müller-Nurasyid, M, Nauck, M, Nivard, M, Penninx, B, Perola, M, Pervjakova, N, Pierce, B, Powell, J, Prokisch, H, Psaty, B, Raitakari, O, Ring, S, Ripatti, S, Rotzschke, O, Ruëger, S, Saha, A, Scholz, M, Schramm, K, Seppälä, I, Stumvoll, M, Sullivan, P, Teumer, A, Thiery, J, Tong, L, Tönjes, A, van Dongen, J, van Meurs, J, Verlouw, J, Völker, U, Võsa, U, Yaghootkar, H, Zeng, B, McRae, AF, Visscher, PM, Zeng, J & Yang, J 2018, 'Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes', Nature Communications, vol. 9, no. 1, 2941. https://doi.org/10.1038/s41467-018-04951-w

TY - JOUR

T1 - Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes

AU - Xue, A.

AU - Wu, Y.

AU - Zhu, Z.

AU - Zhang, F.

AU - Kemper, K.E.

AU - Zheng, Z.

AU - Yengo, L.

AU - Lloyd-Jones, L.R.

AU - Sidorenko, J.

AU - Agbessi, M.

AU - Ahsan, H.

AU - Alves, I.

AU - Andiappan, A.

AU - Awadalla, P.

AU - Battle, A.

AU - Beutner, F.

AU - Bonder, M.J.

AU - Boomsma, D.

AU - Christiansen, M.

AU - Claringbould, A.

AU - Deelen, P.

AU - Esko, T.

AU - Favé, M.-J.

AU - Franke, L.

AU - Frayling, T.

AU - Gharib, S.

AU - Gibson, G.

AU - Hemani, G.

AU - Jansen, R.

AU - Kähönen, M.

AU - Kalnapenkis, A.

AU - Kasela, S.

AU - Kettunen, J.

AU - Kim, Y.

AU - Kirsten, H.

AU - Kovacs, P.

AU - Krohn, K.

AU - Kronberg-Guzman, J.

AU - Kukushkina, V.

AU - Kutalik, Z.

AU - Lee, B.

AU - Lehtimäki, T.

AU - Loeffler, M.

AU - Marigorta, U.M.

AU - Metspalu, A.

AU - Milani, L.

AU - Müller-Nurasyid, M.

AU - Nauck, M.

AU - Nivard, M.

AU - Penninx, B.

AU - Perola, M.

AU - Pervjakova, N.

AU - Pierce, B.

AU - Powell, J.

AU - Prokisch, H.

AU - Psaty, B.

AU - Raitakari, O.

AU - Ring, S.

AU - Ripatti, S.

AU - Rotzschke, O.

AU - Ruëger, S.

AU - Saha, A.

AU - Scholz, M.

AU - Schramm, K.

AU - Seppälä, I.

AU - Stumvoll, M.

AU - Sullivan, P.

AU - Teumer, A.

AU - Thiery, J.

AU - Tong, L.

AU - Tönjes, A.

AU - van Dongen, J.

AU - van Meurs, J.

AU - Verlouw, J.

AU - Völker, U.

AU - Võsa, U.

AU - Yaghootkar, H.

AU - Zeng, B.

AU - McRae, A.F.

AU - Visscher, P.M.

AU - Zeng, J.

AU - Yang, J.

PY - 2018

Y1 - 2018

KW - 3111 Biomedicine

KW - 3121 General medicine, internal medicine and other clinical medicine

U2 - 10.1038/s41467-018-04951-w

DO - 10.1038/s41467-018-04951-w

M3 - Article

VL - 9

JO - Nature Communications

JF - Nature Communications

SN - 2041-1723

IS - 1

M1 - 2941

ER -