Genome-Wide Copy Number Variant and High-Throughput Transcriptomics Analyses of Placental Tissues Underscore Persisting Child Susceptibility in At-Risk Pregnancies Cleared in Standard Genetic Testing

Darina Czamara; Cristiana Cruceanu; Marius Lahti-Pulkkinen; Linda Dieckmann; Maik Koedel; Susann Sauer; Monika Rex-Haffner; Sara Sammallahti; Eero Kajantie; Hannele Laivuori; Jari Lahti; Katri Räikkönen; Elisabeth B. Binder

doi:10.3390/ijms231911448

Genome-Wide Copy Number Variant and High-Throughput Transcriptomics Analyses of Placental Tissues Underscore Persisting Child Susceptibility in At-Risk Pregnancies Cleared in Standard Genetic Testing

Darina Czamara, Cristiana Cruceanu, Marius Lahti-Pulkkinen, Linda Dieckmann, Maik Koedel, Susann Sauer, Monika Rex-Haffner, Sara Sammallahti, Eero Kajantie, Hannele Laivuori, Jari Lahti, Katri Räikkönen, Elisabeth B. Binder

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	11448
Journal	International Journal of Molecular Sciences
Volume	23
Issue number	19
Number of pages	16
ISSN	1422-0067
DOIs	https://doi.org/10.3390/ijms231911448
Publication status	Published - Oct 2022
MoE publication type	A1 Journal article-refereed

Fields of Science

chorionic villus sampling
congenital malformations
placenta
prenatal testing transcriptome sequencing
EXPRESSION
PREECLAMPSIA
ASSOCIATION
1182 Biochemistry, cell and molecular biology

Access to Document

10.3390/ijms231911448Licence: CC BY

http://hdl.handle.net/10138/349804Licence: CC BY

Cite this

Czamara, D., Cruceanu, C., Lahti-Pulkkinen, M., Dieckmann, L., Koedel, M., Sauer, S., Rex-Haffner, M., Sammallahti, S., Kajantie, E., Laivuori, H., Lahti, J., Räikkönen, K., & Binder, E. B. (2022). Genome-Wide Copy Number Variant and High-Throughput Transcriptomics Analyses of Placental Tissues Underscore Persisting Child Susceptibility in At-Risk Pregnancies Cleared in Standard Genetic Testing. International Journal of Molecular Sciences, 23(19), Article 11448. https://doi.org/10.3390/ijms231911448

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title = "Genome-Wide Copy Number Variant and High-Throughput Transcriptomics Analyses of Placental Tissues Underscore Persisting Child Susceptibility in At-Risk Pregnancies Cleared in Standard Genetic Testing",

keywords = "chorionic villus sampling, congenital malformations, placenta, prenatal testing transcriptome sequencing, EXPRESSION, PREECLAMPSIA, ASSOCIATION, 1182 Biochemistry, cell and molecular biology",

author = "Darina Czamara and Cristiana Cruceanu and Marius Lahti-Pulkkinen and Linda Dieckmann and Maik Koedel and Susann Sauer and Monika Rex-Haffner and Sara Sammallahti and Eero Kajantie and Hannele Laivuori and Jari Lahti and Katri R{\"a}ikk{\"o}nen and Binder, {Elisabeth B.}",

year = "2022",

month = oct,

doi = "10.3390/ijms231911448",

language = "English",

volume = "23",

journal = "International Journal of Molecular Sciences",

issn = "1422-0067",

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Czamara, D, Cruceanu, C, Lahti-Pulkkinen, M, Dieckmann, L, Koedel, M, Sauer, S, Rex-Haffner, M, Sammallahti, S, Kajantie, E , Laivuori, H , Lahti, J , Räikkönen, K & Binder, EB 2022, 'Genome-Wide Copy Number Variant and High-Throughput Transcriptomics Analyses of Placental Tissues Underscore Persisting Child Susceptibility in At-Risk Pregnancies Cleared in Standard Genetic Testing', International Journal of Molecular Sciences, vol. 23, no. 19, 11448. https://doi.org/10.3390/ijms231911448

Genome-Wide Copy Number Variant and High-Throughput Transcriptomics Analyses of Placental Tissues Underscore Persisting Child Susceptibility in At-Risk Pregnancies Cleared in Standard Genetic Testing. / Czamara, Darina; Cruceanu, Cristiana; Lahti-Pulkkinen, Marius et al.
In: International Journal of Molecular Sciences, Vol. 23, No. 19, 11448, 10.2022.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - Genome-Wide Copy Number Variant and High-Throughput Transcriptomics Analyses of Placental Tissues Underscore Persisting Child Susceptibility in At-Risk Pregnancies Cleared in Standard Genetic Testing

AU - Czamara, Darina

AU - Cruceanu, Cristiana

AU - Lahti-Pulkkinen, Marius

AU - Dieckmann, Linda

AU - Koedel, Maik

AU - Sauer, Susann

AU - Rex-Haffner, Monika

AU - Sammallahti, Sara

AU - Kajantie, Eero

AU - Laivuori, Hannele

AU - Lahti, Jari

AU - Räikkönen, Katri

AU - Binder, Elisabeth B.

PY - 2022/10

Y1 - 2022/10

KW - chorionic villus sampling

KW - congenital malformations

KW - placenta

KW - prenatal testing transcriptome sequencing

KW - EXPRESSION

KW - PREECLAMPSIA

KW - ASSOCIATION

KW - 1182 Biochemistry, cell and molecular biology

U2 - 10.3390/ijms231911448

DO - 10.3390/ijms231911448

M3 - Article

SN - 1422-0067

VL - 23

JO - International Journal of Molecular Sciences

JF - International Journal of Molecular Sciences

IS - 19

M1 - 11448

ER -

Czamara D, Cruceanu C, Lahti-Pulkkinen M, Dieckmann L, Koedel M, Sauer S et al. Genome-Wide Copy Number Variant and High-Throughput Transcriptomics Analyses of Placental Tissues Underscore Persisting Child Susceptibility in At-Risk Pregnancies Cleared in Standard Genetic Testing. International Journal of Molecular Sciences. 2022 Oct;23(19):11448. doi: 10.3390/ijms231911448