Genome-wide physical activity interactions in adiposity. A meta-analysis of 200,452 adults

Mariaelisa Graff; Robert A. Scott; Anne E. Justice; Kristin L. Young; Mary F. Feitosa; Llilda Barata; Thomas W. Winkler; Audrey Y. Chu; Anubha Mahajan; David Hadley; Luting Xue; Tsegaselassie Workalemahu; Nancy L. Heard-Costa; Marcel den Hoed; Tarunveer S. Ahluwalia; Qibin Qi; Julius S. Ngwa; Frida Renstrom; Lydia Quaye; John D. Eicher; James E. Hayes; Marilyn Cornelis; Zoltan Kutalik; Elise Lim; Jian'an Luan; Jennifer E. Huffman; Weihua Zhang; Wei Zhao; Paula J. Griffin; Toomas Haller; Shafqat Ahmad; Pedro M. Marques-Vidal; Stephanie Bien; Loic Yengo; Alexander Teumer; Albert Vernon Smith; Meena Kumari; Marie Neergaard Harder; Johanne Marie Justesen; Marcus E. Kleber; Mette Hollensted; Kurt Lohman; Natalia V. Rivera; John B. Whitfield; Kati Kristiansson; Aki S. Havulinna; Heikki A. Koistinen; Markus Perola; Jaakko Tuomilehto; Mika Kivimaki; CHARGE Consortium; EPIC-InterAct Consortium; PAGe Consortium

doi:10.1371/journal.pgen.1006528

Genome-wide physical activity interactions in adiposity. A meta-analysis of 200,452 adults

Mariaelisa Graff, Robert A. Scott, Anne E. Justice, Kristin L. Young, Mary F. Feitosa, Llilda Barata, Thomas W. Winkler, Audrey Y. Chu, Anubha Mahajan, David Hadley, Luting Xue, Tsegaselassie Workalemahu, Nancy L. Heard-Costa, Marcel den Hoed, Tarunveer S. Ahluwalia, Qibin Qi, Julius S. Ngwa, Frida Renstrom, Lydia Quaye, John D. EicherJames E. Hayes, Marilyn Cornelis, Zoltan Kutalik, Elise Lim, Jian'an Luan, Jennifer E. Huffman, Weihua Zhang, Wei Zhao, Paula J. Griffin, Toomas Haller, Shafqat Ahmad, Pedro M. Marques-Vidal, Stephanie Bien, Loic Yengo, Alexander Teumer, Albert Vernon Smith, Meena Kumari, Marie Neergaard Harder, Johanne Marie Justesen, Marcus E. Kleber, Mette Hollensted, Kurt Lohman, Natalia V. Rivera, John B. Whitfield, Kati Kristiansson, Aki S. Havulinna, Heikki A. Koistinen, Markus Perola, Jaakko Tuomilehto, Mika Kivimaki, CHARGE Consortium, EPIC-InterAct Consortium, PAGe Consortium

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	1006528
Journal	PLoS Genetics
Volume	13
Issue number	4
Number of pages	26
ISSN	1553-7404
DOIs	https://doi.org/10.1371/journal.pgen.1006528
Publication status	Published - Apr 2017
MoE publication type	A1 Journal article-refereed

Fields of Science

BODY-MASS INDEX
REACTIVE PROTEIN-LEVELS
GENE-EXPRESSION
IDENTICAL-TWINS
ADIPOCYTE DIFFERENTIATION
ASSOCIATION METAANALYSIS
ACTIVITY QUESTIONNAIRES
FAT DISTRIBUTION
BINDING PROTEIN
FOOD-INTAKE
3111 Biomedicine
1184 Genetics, developmental biology, physiology

Access to Document

10.1371/journal.pgen.1006528

Genome-wideFinal published version, 2.53 MBLicence: CC BY

Cite this

Graff, M., Scott, R. A., Justice, A. E., Young, K. L., Feitosa, M. F., Barata, L., Winkler, T. W., Chu, A. Y., Mahajan, A., Hadley, D., Xue, L., Workalemahu, T., Heard-Costa, N. L., den Hoed, M., Ahluwalia, T. S., Qi, Q., Ngwa, J. S., Renstrom, F., Quaye, L., ... PAGe Consortium (2017). Genome-wide physical activity interactions in adiposity. A meta-analysis of 200,452 adults. PLoS Genetics, 13(4), Article 1006528. https://doi.org/10.1371/journal.pgen.1006528

@article{35fce286e4c647fe8764583272d8f895,

title = "Genome-wide physical activity interactions in adiposity. A meta-analysis of 200,452 adults",

keywords = "BODY-MASS INDEX, REACTIVE PROTEIN-LEVELS, GENE-EXPRESSION, IDENTICAL-TWINS, ADIPOCYTE DIFFERENTIATION, ASSOCIATION METAANALYSIS, ACTIVITY QUESTIONNAIRES, FAT DISTRIBUTION, BINDING PROTEIN, FOOD-INTAKE, 3111 Biomedicine, 1184 Genetics, developmental biology, physiology",

author = "Mariaelisa Graff and Scott, {Robert A.} and Justice, {Anne E.} and Young, {Kristin L.} and Feitosa, {Mary F.} and Llilda Barata and Winkler, {Thomas W.} and Chu, {Audrey Y.} and Anubha Mahajan and David Hadley and Luting Xue and Tsegaselassie Workalemahu and Heard-Costa, {Nancy L.} and {den Hoed}, Marcel and Ahluwalia, {Tarunveer S.} and Qibin Qi and Ngwa, {Julius S.} and Frida Renstrom and Lydia Quaye and Eicher, {John D.} and Hayes, {James E.} and Marilyn Cornelis and Zoltan Kutalik and Elise Lim and Jian'an Luan and Huffman, {Jennifer E.} and Weihua Zhang and Wei Zhao and Griffin, {Paula J.} and Toomas Haller and Shafqat Ahmad and Marques-Vidal, {Pedro M.} and Stephanie Bien and Loic Yengo and Alexander Teumer and Smith, {Albert Vernon} and Meena Kumari and Harder, {Marie Neergaard} and Justesen, {Johanne Marie} and Kleber, {Marcus E.} and Mette Hollensted and Kurt Lohman and Rivera, {Natalia V.} and Whitfield, {John B.} and Kati Kristiansson and Havulinna, {Aki S.} and Koistinen, {Heikki A.} and Markus Perola and Jaakko Tuomilehto and Mika Kivimaki and {CHARGE Consortium} and {EPIC-InterAct Consortium} and {PAGe Consortium}",

year = "2017",

month = apr,

doi = "10.1371/journal.pgen.1006528",

language = "English",

volume = "13",

journal = "PLoS Genetics",

issn = "1553-7404",

publisher = "Public Library of Science",

number = "4",

}

Graff, M, Scott, RA, Justice, AE, Young, KL, Feitosa, MF, Barata, L, Winkler, TW, Chu, AY, Mahajan, A, Hadley, D, Xue, L, Workalemahu, T, Heard-Costa, NL, den Hoed, M, Ahluwalia, TS, Qi, Q, Ngwa, JS, Renstrom, F, Quaye, L, Eicher, JD, Hayes, JE, Cornelis, M, Kutalik, Z, Lim, E, Luan, J, Huffman, JE, Zhang, W, Zhao, W, Griffin, PJ, Haller, T, Ahmad, S, Marques-Vidal, PM, Bien, S, Yengo, L, Teumer, A, Smith, AV, Kumari, M, Harder, MN, Justesen, JM, Kleber, ME, Hollensted, M, Lohman, K, Rivera, NV, Whitfield, JB, Kristiansson, K, Havulinna, AS , Koistinen, HA , Perola, M , Tuomilehto, J , Kivimaki, M, CHARGE Consortium, EPIC-InterAct Consortium & PAGe Consortium 2017, 'Genome-wide physical activity interactions in adiposity. A meta-analysis of 200,452 adults', PLoS Genetics, vol. 13, no. 4, 1006528. https://doi.org/10.1371/journal.pgen.1006528

TY - JOUR

T1 - Genome-wide physical activity interactions in adiposity. A meta-analysis of 200,452 adults

AU - Graff, Mariaelisa

AU - Scott, Robert A.

AU - Justice, Anne E.

AU - Young, Kristin L.

AU - Feitosa, Mary F.

AU - Barata, Llilda

AU - Winkler, Thomas W.

AU - Chu, Audrey Y.

AU - Mahajan, Anubha

AU - Hadley, David

AU - Xue, Luting

AU - Workalemahu, Tsegaselassie

AU - Heard-Costa, Nancy L.

AU - den Hoed, Marcel

AU - Ahluwalia, Tarunveer S.

AU - Qi, Qibin

AU - Ngwa, Julius S.

AU - Renstrom, Frida

AU - Quaye, Lydia

AU - Eicher, John D.

AU - Hayes, James E.

AU - Cornelis, Marilyn

AU - Kutalik, Zoltan

AU - Lim, Elise

AU - Luan, Jian'an

AU - Huffman, Jennifer E.

AU - Zhang, Weihua

AU - Zhao, Wei

AU - Griffin, Paula J.

AU - Haller, Toomas

AU - Ahmad, Shafqat

AU - Marques-Vidal, Pedro M.

AU - Bien, Stephanie

AU - Yengo, Loic

AU - Teumer, Alexander

AU - Smith, Albert Vernon

AU - Kumari, Meena

AU - Harder, Marie Neergaard

AU - Justesen, Johanne Marie

AU - Kleber, Marcus E.

AU - Hollensted, Mette

AU - Lohman, Kurt

AU - Rivera, Natalia V.

AU - Whitfield, John B.

AU - Kristiansson, Kati

AU - Havulinna, Aki S.

AU - Koistinen, Heikki A.

AU - Perola, Markus

AU - Tuomilehto, Jaakko

AU - Kivimaki, Mika

AU - CHARGE Consortium

AU - EPIC-InterAct Consortium

AU - PAGe Consortium

PY - 2017/4

Y1 - 2017/4

KW - BODY-MASS INDEX

KW - REACTIVE PROTEIN-LEVELS

KW - GENE-EXPRESSION

KW - IDENTICAL-TWINS

KW - ADIPOCYTE DIFFERENTIATION

KW - ASSOCIATION METAANALYSIS

KW - ACTIVITY QUESTIONNAIRES

KW - FAT DISTRIBUTION

KW - BINDING PROTEIN

KW - FOOD-INTAKE

KW - 3111 Biomedicine

KW - 1184 Genetics, developmental biology, physiology

U2 - 10.1371/journal.pgen.1006528

DO - 10.1371/journal.pgen.1006528

M3 - Article

SN - 1553-7404

VL - 13

JO - PLoS Genetics

JF - PLoS Genetics

IS - 4

M1 - 1006528

ER -