Glucuronidation of estrone and 16 alpha-hydroxyestrone by human UGT enzymes

The key roles of UGT1A10 and UGT2B7

Roope A. Kallionpää, Erkka Järvinen, Moshe Finel

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalJournal of Steroid Biochemistry and Molecular Biology
Volume154
Pages (from-to)104-111
Number of pages8
ISSN0960-0760
DOIs
Publication statusPublished - Nov 2015
MoE publication typeA1 Journal article-refereed

Fields of Science

  • Estrone glucuronidation
  • UGT1A10
  • 16 alpha-Hydroxyestrone conjugation
  • UGT2B7
  • Extrahepatic glucuronidation
  • Intestine microsomes
  • HUMAN UDP-GLUCURONOSYLTRANSFERASE
  • BREAST-CANCER-CELLS
  • TANDEM MASS-SPECTROMETRY
  • METABOLITES
  • ESTRADIOL
  • 1A10
  • DETOXIFICATION
  • EXPRESSION
  • ESTROGENS
  • ISOFORM
  • 1182 Biochemistry, cell and molecular biology
  • 317 Pharmacy

Cite this

@article{bae7469390be4702a01ec638a991c682,
title = "Glucuronidation of estrone and 16 alpha-hydroxyestrone by human UGT enzymes: The key roles of UGT1A10 and UGT2B7",
keywords = "Estrone glucuronidation, UGT1A10, 16 alpha-Hydroxyestrone conjugation, UGT2B7, Extrahepatic glucuronidation, Intestine microsomes, HUMAN UDP-GLUCURONOSYLTRANSFERASE, BREAST-CANCER-CELLS, TANDEM MASS-SPECTROMETRY, METABOLITES, ESTRADIOL, 1A10, DETOXIFICATION, EXPRESSION, ESTROGENS, ISOFORM, 1182 Biochemistry, cell and molecular biology, 317 Pharmacy",
author = "Kallionp{\"a}{\"a}, {Roope A.} and Erkka J{\"a}rvinen and Moshe Finel",
year = "2015",
month = "11",
doi = "10.1016/j.jsbmb.2015.07.013",
language = "English",
volume = "154",
pages = "104--111",
journal = "Journal of Steroid Biochemistry and Molecular Biology",
issn = "0960-0760",
publisher = "Elsevier Scientific Publ. Co",

}

Glucuronidation of estrone and 16 alpha-hydroxyestrone by human UGT enzymes : The key roles of UGT1A10 and UGT2B7. / Kallionpää, Roope A.; Järvinen, Erkka; Finel, Moshe.

In: Journal of Steroid Biochemistry and Molecular Biology, Vol. 154, 11.2015, p. 104-111.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Glucuronidation of estrone and 16 alpha-hydroxyestrone by human UGT enzymes

T2 - The key roles of UGT1A10 and UGT2B7

AU - Kallionpää, Roope A.

AU - Järvinen, Erkka

AU - Finel, Moshe

PY - 2015/11

Y1 - 2015/11

KW - Estrone glucuronidation

KW - UGT1A10

KW - 16 alpha-Hydroxyestrone conjugation

KW - UGT2B7

KW - Extrahepatic glucuronidation

KW - Intestine microsomes

KW - HUMAN UDP-GLUCURONOSYLTRANSFERASE

KW - BREAST-CANCER-CELLS

KW - TANDEM MASS-SPECTROMETRY

KW - METABOLITES

KW - ESTRADIOL

KW - 1A10

KW - DETOXIFICATION

KW - EXPRESSION

KW - ESTROGENS

KW - ISOFORM

KW - 1182 Biochemistry, cell and molecular biology

KW - 317 Pharmacy

U2 - 10.1016/j.jsbmb.2015.07.013

DO - 10.1016/j.jsbmb.2015.07.013

M3 - Article

VL - 154

SP - 104

EP - 111

JO - Journal of Steroid Biochemistry and Molecular Biology

JF - Journal of Steroid Biochemistry and Molecular Biology

SN - 0960-0760

ER -