Grapefruit Juice Greatly Reduces the Plasma Concentrations of the OATP2B1 and CYP3A4 Substrate Aliskiren

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalClinical Pharmacology and Therapeutics
Volume88
Issue number3
Pages (from-to)339-342
Number of pages4
ISSN0009-9236
DOIs
Publication statusPublished - 2010
MoE publication typeA1 Journal article-refereed

Fields of Science

  • RENIN INHIBITOR ALISKIREN
  • P-GLYCOPROTEIN
  • ORAL AVAILABILITY
  • CITRUS JUICES
  • DRUG
  • PHARMACOKINETICS
  • ATORVASTATIN
  • DISPOSITION
  • EXPRESSION
  • INCREASES
  • 312 Clinical medicine

Cite this

@article{0dd7550164d4409eb85a175198320d0a,
title = "Grapefruit Juice Greatly Reduces the Plasma Concentrations of the OATP2B1 and CYP3A4 Substrate Aliskiren",
keywords = "RENIN INHIBITOR ALISKIREN, P-GLYCOPROTEIN, ORAL AVAILABILITY, CITRUS JUICES, DRUG, PHARMACOKINETICS, ATORVASTATIN, DISPOSITION, EXPRESSION, INCREASES, 312 Clinical medicine",
author = "Tuija Tapaninen and Neuvonen, {Pertti J.} and Mikko Niemi",
year = "2010",
doi = "10.1038/clpt.2010.101",
language = "English",
volume = "88",
pages = "339--342",
journal = "Clinical Pharmacology and Therapeutics",
issn = "0009-9236",
publisher = "Wiley",
number = "3",

}

Grapefruit Juice Greatly Reduces the Plasma Concentrations of the OATP2B1 and CYP3A4 Substrate Aliskiren. / Tapaninen, Tuija; Neuvonen, Pertti J.; Niemi, Mikko.

In: Clinical Pharmacology and Therapeutics, Vol. 88, No. 3, 2010, p. 339-342.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Grapefruit Juice Greatly Reduces the Plasma Concentrations of the OATP2B1 and CYP3A4 Substrate Aliskiren

AU - Tapaninen, Tuija

AU - Neuvonen, Pertti J.

AU - Niemi, Mikko

PY - 2010

Y1 - 2010

KW - RENIN INHIBITOR ALISKIREN

KW - P-GLYCOPROTEIN

KW - ORAL AVAILABILITY

KW - CITRUS JUICES

KW - DRUG

KW - PHARMACOKINETICS

KW - ATORVASTATIN

KW - DISPOSITION

KW - EXPRESSION

KW - INCREASES

KW - 312 Clinical medicine

U2 - 10.1038/clpt.2010.101

DO - 10.1038/clpt.2010.101

M3 - Article

VL - 88

SP - 339

EP - 342

JO - Clinical Pharmacology and Therapeutics

JF - Clinical Pharmacology and Therapeutics

SN - 0009-9236

IS - 3

ER -