Helper-dependent adenovirus-mediated gene transfer of a secreted LDL receptor/transferrin chimeric protein reduces aortic atherosclerosis in LDL receptor-deficient mice

Eleonora Leggiero, Giuseppe Labruna, Laura Iaffaldano, Barbara Lombardo, Adelaide Greco, Dario Fiorenza, Matteo Gramanzini, Donatella Montanaro, Alfonso Baldi, Vincenzo Cerullo, Lucia Sacchetti, Lucio Pastore

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalGene Therapy (Basingstoke)
Volume26
Issue number3-4
Pages (from-to)121-130
Number of pages10
ISSN0969-7128
DOIs
Publication statusPublished - Apr 2019
MoE publication typeA1 Journal article-refereed

Fields of Science

  • A-I
  • FAMILIAL HYPERCHOLESTEROLEMIA
  • FUNCTIONAL-EVALUATION
  • IMMUNE-RESPONSES
  • THERAPEUTIC TOOL
  • FUSION PROTEIN
  • AAV-VECTORS
  • MOUSE MODEL
  • EXPRESSION
  • LIVER
  • 1182 Biochemistry, cell and molecular biology
  • 1183 Plant biology, microbiology, virology
  • 1184 Genetics, developmental biology, physiology

Cite this