Hierarchical Bayesian Model for Rare Variant Association Analysis Integrating Genotype Uncertainty in Human Sequence Data

Liang He, Janne Pitkaniemi, Antti-Pekka Sarin, Veikko Salomaa, Mikko J. Sillanpaa, Samuli Ripatti

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalGenetic Epidemiology
Volume39
Issue number2
Pages (from-to)89-100
Number of pages12
ISSN0741-0395
DOIs
Publication statusPublished - Feb 2015
MoE publication typeA1 Journal article-refereed

Fields of Science

  • rare variant
  • classification error
  • shrinkage-based Bayesian variable selection
  • LDL-C
  • FAMILIAL HYPERCHOLESTEROLEMIA
  • GENETIC ASSOCIATION
  • NORTH KARELIA
  • REGRESSION
  • CHOLESTEROL
  • FREQUENCY
  • FRAMEWORK
  • SELECTION
  • MUTATION
  • FINLAND
  • 3142 Public health care science, environmental and occupational health

Cite this

@article{f4ab84a7afde49a1afae974c9df10022,
title = "Hierarchical Bayesian Model for Rare Variant Association Analysis Integrating Genotype Uncertainty in Human Sequence Data",
keywords = "rare variant, classification error, shrinkage-based Bayesian variable selection, LDL-C, FAMILIAL HYPERCHOLESTEROLEMIA, GENETIC ASSOCIATION, NORTH KARELIA, REGRESSION, CHOLESTEROL, FREQUENCY, FRAMEWORK, SELECTION, MUTATION, FINLAND, 3142 Public health care science, environmental and occupational health",
author = "Liang He and Janne Pitkaniemi and Antti-Pekka Sarin and Veikko Salomaa and Sillanpaa, {Mikko J.} and Samuli Ripatti",
year = "2015",
month = "2",
doi = "10.1002/gepi.21871",
language = "English",
volume = "39",
pages = "89--100",
journal = "Genetic Epidemiology",
issn = "0741-0395",
publisher = "Wiley",
number = "2",

}

Hierarchical Bayesian Model for Rare Variant Association Analysis Integrating Genotype Uncertainty in Human Sequence Data. / He, Liang; Pitkaniemi, Janne; Sarin, Antti-Pekka; Salomaa, Veikko; Sillanpaa, Mikko J.; Ripatti, Samuli.

In: Genetic Epidemiology, Vol. 39, No. 2, 02.2015, p. 89-100.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Hierarchical Bayesian Model for Rare Variant Association Analysis Integrating Genotype Uncertainty in Human Sequence Data

AU - He, Liang

AU - Pitkaniemi, Janne

AU - Sarin, Antti-Pekka

AU - Salomaa, Veikko

AU - Sillanpaa, Mikko J.

AU - Ripatti, Samuli

PY - 2015/2

Y1 - 2015/2

KW - rare variant

KW - classification error

KW - shrinkage-based Bayesian variable selection

KW - LDL-C

KW - FAMILIAL HYPERCHOLESTEROLEMIA

KW - GENETIC ASSOCIATION

KW - NORTH KARELIA

KW - REGRESSION

KW - CHOLESTEROL

KW - FREQUENCY

KW - FRAMEWORK

KW - SELECTION

KW - MUTATION

KW - FINLAND

KW - 3142 Public health care science, environmental and occupational health

U2 - 10.1002/gepi.21871

DO - 10.1002/gepi.21871

M3 - Article

VL - 39

SP - 89

EP - 100

JO - Genetic Epidemiology

JF - Genetic Epidemiology

SN - 0741-0395

IS - 2

ER -