High drug-loaded microspheres enabled by controlled in-droplet precipitation promote functional recovery after spinal cord injury

Wei Li; Jian Chen; Shujie Zhao; Tianhe Huang; Huiyan Ying; Claudia Trujillo; Giuseppina Molinaro; Zheng Zhou; Tao Jiang; Wei Liu; Linwei Li; Yuancheng Bai; Peng Quan; Yaping Ding; Jouni Hirvonen; Guoyong Yin; Helder A. Santos; Jin Fan; Dongfei Liu

doi:10.1038/s41467-022-28787-7

High drug-loaded microspheres enabled by controlled in-droplet precipitation promote functional recovery after spinal cord injury

Wei Li, Jian Chen, Shujie Zhao, Tianhe Huang, Huiyan Ying, Claudia Trujillo, Giuseppina Molinaro, Zheng Zhou, Tao Jiang, Wei Liu, Linwei Li, Yuancheng Bai, Peng Quan, Yaping Ding, Jouni Hirvonen, Guoyong Yin, Helder A. Santos, Jin Fan, Dongfei Liu

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	1262
Journal	Nature Communications
Volume	13
Issue number	1
Number of pages	16
ISSN	2041-1723
DOIs	https://doi.org/10.1038/s41467-022-28787-7
Publication status	Published - 10 Mar 2022
MoE publication type	A1 Journal article-refereed

Fields of Science

POLYMERIC MICROSPHERES
SCAR FORMATION
DELIVERY
METHYLPREDNISOLONE
NANOPARTICLES
SYSTEM
STABILIZATION
NANOCRYSTALS
FABRICATION
MANAGEMENT
317 Pharmacy

Access to Document

10.1038/s41467-022-28787-7Licence: CC BY

s41467-022-28787-7Final published version, 10.9 MBLicence: CC BY

Cite this

Li, W., Chen, J., Zhao, S., Huang, T., Ying, H., Trujillo, C., Molinaro, G., Zhou, Z., Jiang, T., Liu, W., Li, L., Bai, Y., Quan, P., Ding, Y., Hirvonen, J., Yin, G., Santos, H. A., Fan, J., & Liu, D. (2022). High drug-loaded microspheres enabled by controlled in-droplet precipitation promote functional recovery after spinal cord injury. Nature Communications, 13(1), Article 1262. https://doi.org/10.1038/s41467-022-28787-7

@article{e134b10ff8f0429782255b1a20f0cb92,

title = "High drug-loaded microspheres enabled by controlled in-droplet precipitation promote functional recovery after spinal cord injury",

keywords = "POLYMERIC MICROSPHERES, SCAR FORMATION, DELIVERY, METHYLPREDNISOLONE, NANOPARTICLES, SYSTEM, STABILIZATION, NANOCRYSTALS, FABRICATION, MANAGEMENT, 317 Pharmacy",

author = "Wei Li and Jian Chen and Shujie Zhao and Tianhe Huang and Huiyan Ying and Claudia Trujillo and Giuseppina Molinaro and Zheng Zhou and Tao Jiang and Wei Liu and Linwei Li and Yuancheng Bai and Peng Quan and Yaping Ding and Jouni Hirvonen and Guoyong Yin and Santos, {Helder A.} and Jin Fan and Dongfei Liu",

year = "2022",

month = mar,

day = "10",

doi = "10.1038/s41467-022-28787-7",

language = "English",

volume = "13",

journal = "Nature Communications",

issn = "2041-1723",

publisher = "Nature Publishing Group",

number = "1",

}

Li, W, Chen, J, Zhao, S, Huang, T, Ying, H, Trujillo, C, Molinaro, G, Zhou, Z, Jiang, T, Liu, W, Li, L, Bai, Y, Quan, P, Ding, Y , Hirvonen, J, Yin, G, Santos, HA, Fan, J & Liu, D 2022, 'High drug-loaded microspheres enabled by controlled in-droplet precipitation promote functional recovery after spinal cord injury', Nature Communications, vol. 13, no. 1, 1262. https://doi.org/10.1038/s41467-022-28787-7

TY - JOUR

T1 - High drug-loaded microspheres enabled by controlled in-droplet precipitation promote functional recovery after spinal cord injury

AU - Li, Wei

AU - Chen, Jian

AU - Zhao, Shujie

AU - Huang, Tianhe

AU - Ying, Huiyan

AU - Trujillo, Claudia

AU - Molinaro, Giuseppina

AU - Zhou, Zheng

AU - Jiang, Tao

AU - Liu, Wei

AU - Li, Linwei

AU - Bai, Yuancheng

AU - Quan, Peng

AU - Ding, Yaping

AU - Hirvonen, Jouni

AU - Yin, Guoyong

AU - Santos, Helder A.

AU - Fan, Jin

AU - Liu, Dongfei

PY - 2022/3/10

Y1 - 2022/3/10

KW - POLYMERIC MICROSPHERES

KW - SCAR FORMATION

KW - DELIVERY

KW - METHYLPREDNISOLONE

KW - NANOPARTICLES

KW - SYSTEM

KW - STABILIZATION

KW - NANOCRYSTALS

KW - FABRICATION

KW - MANAGEMENT

KW - 317 Pharmacy

U2 - 10.1038/s41467-022-28787-7

DO - 10.1038/s41467-022-28787-7

M3 - Article

SN - 2041-1723

VL - 13

JO - Nature Communications

JF - Nature Communications

IS - 1

M1 - 1262

ER -