HSP70 induces liver X receptor pathway activation and cholesterol reduction in vitro and in vivo

Burcin Gungor; Lauri Vanharanta; Maarit Hölttä-Vuori; Juho Pirhonen; Nikolaj H. T. Petersen; Silvia Gramolelli; Päivi M. Ojala; Thomas Kirkegaard; Elina Ikonen

doi:10.1016/j.molmet.2019.07.005

HSP70 induces liver X receptor pathway activation and cholesterol reduction in vitro and in vivo

Burcin Gungor, Lauri Vanharanta, Maarit Hölttä-Vuori, Juho Pirhonen, Nikolaj H. T. Petersen, Silvia Gramolelli, Päivi M. Ojala, Thomas Kirkegaard, Elina Ikonen

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Molecular metabolism
Volume	28
Pages (from-to)	135-143
Number of pages	9
ISSN	2212-8778
DOIs	https://doi.org/10.1016/j.molmet.2019.07.005
Publication status	Published - Oct 2019
MoE publication type	A1 Journal article-refereed

Fields of Science

Cholesterol metabolism
Liver X receptor
Heat shock protein
Human macrophages
Transcriptional regulation
HEAT-SHOCK-PROTEINS
HEAT-SHOCK-PROTEIN-70
ATHEROSCLEROSIS
MECHANISMS
TRANSPORT
MEMBRANE
EFFLUX
HSP90
3121 General medicine, internal medicine and other clinical medicine
3111 Biomedicine

Access to Document

10.1016/j.molmet.2019.07.005

1-s2.0-S2212877819306027-mainFinal published version, 2 MBLicence: CC BY-NC-ND

Cite this

@article{4a5be61c1c014eb6b39063e7f230370a,

title = "HSP70 induces liver X receptor pathway activation and cholesterol reduction in vitro and in vivo",

keywords = "Cholesterol metabolism, Liver X receptor, Heat shock protein, Human macrophages, Transcriptional regulation, HEAT-SHOCK-PROTEINS, HEAT-SHOCK-PROTEIN-70, ATHEROSCLEROSIS, MECHANISMS, TRANSPORT, MEMBRANE, EFFLUX, HSP90, 3121 General medicine, internal medicine and other clinical medicine, 3111 Biomedicine",

author = "Burcin Gungor and Lauri Vanharanta and Maarit H{\"o}ltt{\"a}-Vuori and Juho Pirhonen and Petersen, {Nikolaj H. T.} and Silvia Gramolelli and Ojala, {P{\"a}ivi M.} and Thomas Kirkegaard and Elina Ikonen",

year = "2019",

month = oct,

doi = "10.1016/j.molmet.2019.07.005",

language = "English",

volume = "28",

pages = "135--143",

journal = "Molecular metabolism",

issn = "2212-8778",

publisher = "Elsevier Scientific Publ. Co",

}

TY - JOUR

T1 - HSP70 induces liver X receptor pathway activation and cholesterol reduction in vitro and in vivo

AU - Gungor, Burcin

AU - Vanharanta, Lauri

AU - Hölttä-Vuori, Maarit

AU - Pirhonen, Juho

AU - Petersen, Nikolaj H. T.

AU - Gramolelli, Silvia

AU - Ojala, Päivi M.

AU - Kirkegaard, Thomas

AU - Ikonen, Elina

PY - 2019/10

Y1 - 2019/10

KW - Cholesterol metabolism

KW - Liver X receptor

KW - Heat shock protein

KW - Human macrophages

KW - Transcriptional regulation

KW - HEAT-SHOCK-PROTEINS

KW - HEAT-SHOCK-PROTEIN-70

KW - ATHEROSCLEROSIS

KW - MECHANISMS

KW - TRANSPORT

KW - MEMBRANE

KW - EFFLUX

KW - HSP90

KW - 3121 General medicine, internal medicine and other clinical medicine

KW - 3111 Biomedicine

U2 - 10.1016/j.molmet.2019.07.005

DO - 10.1016/j.molmet.2019.07.005

M3 - Article

SN - 2212-8778

VL - 28

SP - 135

EP - 143

JO - Molecular metabolism

JF - Molecular metabolism

ER -