Human PNPLA3-I148M variant increases hepatic retention of polyunsaturated fatty acids

Panu K. Luukkonen, Auli Nick, Maarit Hölttä-Vuori, Christoph Thiele, Elina Isokuortti, Susanna Lallukka-Brück, You Zhou, Antti Hakkarainen, Nina Lundbom, Markku Peltonen, Marju Orho-Melander, Matej Oresic, Tuulia Hyötyläinen, Leanne Hodson, Elina Ikonen, Hannele Yki-Järvinen

Research output: Contribution to journal › Article › Scientific › peer-review

Original languageEnglish
Article number127902
JournalJCI INSIGHT
Volume4
Issue number16
Number of pages13
ISSN2379-3708
DOIs
Publication statusPublished - 22 Aug 2019
MoE publication typeA1 Journal article-refereed

Fields of Science

  • LIVER FAT
  • WEIGHT-LOSS
  • TRIGLYCERIDE
  • METABOLISM
  • I148M
  • LIPOPROTEIN
  • EXPRESSION
  • OXIDATION
  • DISEASE
  • GREATER
  • 3111 Biomedicine

Cite this

Luukkonen, Panu K. ; Nick, Auli ; Hölttä-Vuori, Maarit ; Thiele, Christoph ; Isokuortti, Elina ; Lallukka-Brück, Susanna ; Zhou, You ; Hakkarainen, Antti ; Lundbom, Nina ; Peltonen, Markku ; Orho-Melander, Marju ; Oresic, Matej ; Hyötyläinen, Tuulia ; Hodson, Leanne ; Ikonen, Elina ; Yki-Järvinen, Hannele. / Human PNPLA3-I148M variant increases hepatic retention of polyunsaturated fatty acids. In: JCI INSIGHT. 2019 ; Vol. 4, No. 16.
@article{833519121fc14a878e3b9d35491eb694,
title = "Human PNPLA3-I148M variant increases hepatic retention of polyunsaturated fatty acids",
keywords = "LIVER FAT, WEIGHT-LOSS, TRIGLYCERIDE, METABOLISM, I148M, LIPOPROTEIN, EXPRESSION, OXIDATION, DISEASE, GREATER, 3111 Biomedicine",
author = "Luukkonen, {Panu K.} and Auli Nick and Maarit H{\"o}ltt{\"a}-Vuori and Christoph Thiele and Elina Isokuortti and Susanna Lallukka-Br{\"u}ck and You Zhou and Antti Hakkarainen and Nina Lundbom and Markku Peltonen and Marju Orho-Melander and Matej Oresic and Tuulia Hy{\"o}tyl{\"a}inen and Leanne Hodson and Elina Ikonen and Hannele Yki-J{\"a}rvinen",
year = "2019",
month = "8",
day = "22",
doi = "10.1172/jci.insight.127902",
language = "English",
volume = "4",
journal = "JCI INSIGHT",
issn = "2379-3708",
publisher = "AMERICAN SOCIETY FOR CLINICAL INVESTIGATION",
number = "16",

}

Luukkonen, PK, Nick, A, Hölttä-Vuori, M, Thiele, C, Isokuortti, E, Lallukka-Brück, S, Zhou, Y, Hakkarainen, A, Lundbom, N, Peltonen, M, Orho-Melander, M, Oresic, M, Hyötyläinen, T, Hodson, L, Ikonen, E & Yki-Järvinen, H 2019, 'Human PNPLA3-I148M variant increases hepatic retention of polyunsaturated fatty acids', JCI INSIGHT, vol. 4, no. 16, 127902. https://doi.org/10.1172/jci.insight.127902

Human PNPLA3-I148M variant increases hepatic retention of polyunsaturated fatty acids. / Luukkonen, Panu K.; Nick, Auli; Hölttä-Vuori, Maarit; Thiele, Christoph; Isokuortti, Elina; Lallukka-Brück, Susanna; Zhou, You; Hakkarainen, Antti; Lundbom, Nina; Peltonen, Markku; Orho-Melander, Marju; Oresic, Matej; Hyötyläinen, Tuulia; Hodson, Leanne; Ikonen, Elina; Yki-Järvinen, Hannele.

In: JCI INSIGHT, Vol. 4, No. 16, 127902, 22.08.2019.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - Human PNPLA3-I148M variant increases hepatic retention of polyunsaturated fatty acids

AU - Luukkonen, Panu K.

AU - Nick, Auli

AU - Hölttä-Vuori, Maarit

AU - Thiele, Christoph

AU - Isokuortti, Elina

AU - Lallukka-Brück, Susanna

AU - Zhou, You

AU - Hakkarainen, Antti

AU - Lundbom, Nina

AU - Peltonen, Markku

AU - Orho-Melander, Marju

AU - Oresic, Matej

AU - Hyötyläinen, Tuulia

AU - Hodson, Leanne

AU - Ikonen, Elina

AU - Yki-Järvinen, Hannele

PY - 2019/8/22

Y1 - 2019/8/22

KW - LIVER FAT

KW - WEIGHT-LOSS

KW - TRIGLYCERIDE

KW - METABOLISM

KW - I148M

KW - LIPOPROTEIN

KW - EXPRESSION

KW - OXIDATION

KW - DISEASE

KW - GREATER

KW - 3111 Biomedicine

U2 - 10.1172/jci.insight.127902

DO - 10.1172/jci.insight.127902

M3 - Article

VL - 4

JO - JCI INSIGHT

JF - JCI INSIGHT

SN - 2379-3708

IS - 16

M1 - 127902

ER -

Luukkonen PK, Nick A, Hölttä-Vuori M, Thiele C, Isokuortti E, Lallukka-Brück S et al. Human PNPLA3-I148M variant increases hepatic retention of polyunsaturated fatty acids. JCI INSIGHT. 2019 Aug 22;4(16). 127902. https://doi.org/10.1172/jci.insight.127902

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