Hydroxysteroid (17 beta) Dehydrogenase 7 Activity Is Essential for Fetal de Novo Cholesterol Synthesis and for Neuroectodermal Survival and Cardiovascular Differentiation in Early Mouse Embryos

Heli Jokela; Pia Rantakari; Tarja Lamminen; Leena Strauss; Roxana Ola; Aino-Liisa Mutka; Helena Gylling; Tatu Miettinen; Pirjo Pakarinen; Kirsi Sainio; Matti Poutanen

doi:10.1210/en.2009-0928

Hydroxysteroid (17 beta) Dehydrogenase 7 Activity Is Essential for Fetal de Novo Cholesterol Synthesis and for Neuroectodermal Survival and Cardiovascular Differentiation in Early Mouse Embryos

Heli Jokela, Pia Rantakari, Tarja Lamminen, Leena Strauss, Roxana Ola, Aino-Liisa Mutka, Helena Gylling, Tatu Miettinen, Pirjo Pakarinen, Kirsi Sainio, Matti Poutanen

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Endocrinology
Volume	151
Issue number	4
Pages (from-to)	1884-1892
Number of pages	9
ISSN	0013-7227
DOIs	https://doi.org/10.1210/en.2009-0928
Publication status	Published - 2010
MoE publication type	A1 Journal article-refereed

Fields of Science

DOMINANT CHONDRODYSPLASIA PUNCTATA
LEMLI-OPITZ-SYNDROME
3-KETOSTEROID REDUCTASE
PROLACTIN RECEPTOR
ESCHERICHIA-COLI
INBORN ERROR
BARE PATCHES
MICE
BIOSYNTHESIS
GENE
311 Basic medicine

Access to Document

10.1210/en.2009-0928

Cite this

Jokela, H., Rantakari, P., Lamminen, T., Strauss, L., Ola, R., Mutka, A-L., Gylling, H., Miettinen, T., Pakarinen, P., Sainio, K., & Poutanen, M. (2010). Hydroxysteroid (17 beta) Dehydrogenase 7 Activity Is Essential for Fetal de Novo Cholesterol Synthesis and for Neuroectodermal Survival and Cardiovascular Differentiation in Early Mouse Embryos. Endocrinology, 151(4), 1884-1892. https://doi.org/10.1210/en.2009-0928

Jokela, Heli ; Rantakari, Pia ; Lamminen, Tarja ; Strauss, Leena ; Ola, Roxana ; Mutka, Aino-Liisa ; Gylling, Helena ; Miettinen, Tatu ; Pakarinen, Pirjo ; Sainio, Kirsi ; Poutanen, Matti. / Hydroxysteroid (17 beta) Dehydrogenase 7 Activity Is Essential for Fetal de Novo Cholesterol Synthesis and for Neuroectodermal Survival and Cardiovascular Differentiation in Early Mouse Embryos. In: Endocrinology. 2010 ; Vol. 151, No. 4. pp. 1884-1892.

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title = "Hydroxysteroid (17 beta) Dehydrogenase 7 Activity Is Essential for Fetal de Novo Cholesterol Synthesis and for Neuroectodermal Survival and Cardiovascular Differentiation in Early Mouse Embryos",

keywords = "DOMINANT CHONDRODYSPLASIA PUNCTATA, LEMLI-OPITZ-SYNDROME, 3-KETOSTEROID REDUCTASE, PROLACTIN RECEPTOR, ESCHERICHIA-COLI, INBORN ERROR, BARE PATCHES, MICE, BIOSYNTHESIS, GENE, 311 Basic medicine",

author = "Heli Jokela and Pia Rantakari and Tarja Lamminen and Leena Strauss and Roxana Ola and Aino-Liisa Mutka and Helena Gylling and Tatu Miettinen and Pirjo Pakarinen and Kirsi Sainio and Matti Poutanen",

year = "2010",

doi = "10.1210/en.2009-0928",

language = "English",

volume = "151",

pages = "1884--1892",

journal = "Endocrinology",

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Jokela, H, Rantakari, P, Lamminen, T, Strauss, L, Ola, R, Mutka, A-L, Gylling, H, Miettinen, T, Pakarinen, P, Sainio, K & Poutanen, M 2010, 'Hydroxysteroid (17 beta) Dehydrogenase 7 Activity Is Essential for Fetal de Novo Cholesterol Synthesis and for Neuroectodermal Survival and Cardiovascular Differentiation in Early Mouse Embryos', Endocrinology, vol. 151, no. 4, pp. 1884-1892. https://doi.org/10.1210/en.2009-0928

Hydroxysteroid (17 beta) Dehydrogenase 7 Activity Is Essential for Fetal de Novo Cholesterol Synthesis and for Neuroectodermal Survival and Cardiovascular Differentiation in Early Mouse Embryos. / Jokela, Heli; Rantakari, Pia; Lamminen, Tarja; Strauss, Leena; Ola, Roxana; Mutka, Aino-Liisa; Gylling, Helena; Miettinen, Tatu; Pakarinen, Pirjo; Sainio, Kirsi; Poutanen, Matti.

In: Endocrinology, Vol. 151, No. 4, 2010, p. 1884-1892.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - Hydroxysteroid (17 beta) Dehydrogenase 7 Activity Is Essential for Fetal de Novo Cholesterol Synthesis and for Neuroectodermal Survival and Cardiovascular Differentiation in Early Mouse Embryos

AU - Jokela, Heli

AU - Rantakari, Pia

AU - Lamminen, Tarja

AU - Strauss, Leena

AU - Ola, Roxana

AU - Mutka, Aino-Liisa

AU - Gylling, Helena

AU - Miettinen, Tatu

AU - Pakarinen, Pirjo

AU - Sainio, Kirsi

AU - Poutanen, Matti

PY - 2010

Y1 - 2010

KW - DOMINANT CHONDRODYSPLASIA PUNCTATA

KW - LEMLI-OPITZ-SYNDROME

KW - 3-KETOSTEROID REDUCTASE

KW - PROLACTIN RECEPTOR

KW - ESCHERICHIA-COLI

KW - INBORN ERROR

KW - BARE PATCHES

KW - MICE

KW - BIOSYNTHESIS

KW - GENE

KW - 311 Basic medicine

U2 - 10.1210/en.2009-0928

DO - 10.1210/en.2009-0928

M3 - Article

VL - 151

SP - 1884

EP - 1892

JO - Endocrinology

JF - Endocrinology

SN - 0013-7227

IS - 4

ER -